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@williamrabrown.bsky.social

Fission yeast genomics, epigenetics and centromeres, genome engineering, Russian language, culture and pre-1917 history.

96 Followers  |  147 Following  |  4 Posts  |  Joined: 16.11.2024
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Posts by (@williamrabrown.bsky.social)

So happy to see Mark recognised for his incredible work. Over a ~40 year career he and his group discovered ECF sigma factors, characterised many key developmental regulators of the Streptomyces lifecycle, and identified new mechanisms of bacterial gene regulation, antibiotic action and resistance.

11.12.2025 20:23 โ€” ๐Ÿ‘ 29    ๐Ÿ” 10    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

Millington, J. W., Lopez, J. A., Sajjadian, A. M., Scheffler, R. J., DeFelice, B. C., Ludington, W. B., Good, B. H., O'Brien, L. E., Huang, K. C. (2025). Gut microbe-derived lactic acid optimizes host energy metabolism during starvation. bioRxiv, www.biorxiv.org/content/10.1...

02.11.2025 08:34 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Meet the Presidentโ€™s main man | The Observer An elegant portrait of Jimmy Carterโ€™s hawkish security adviser reveals him to be a pivotal figure in cold war policy

๐Ÿ’ฃ At 3am, the nukes were coming... Or so Zbigniew Brzezinski was told.
Edward Luce revisits one of the Cold Warโ€™s most surreal nights โ€” and the legacy of Carterโ€™s underrated strategist.
Read in the @ObserverUK: Meet the Presidentโ€™s Main Man by John Bew observer.co.uk/culture/book...

30.07.2025 15:11 โ€” ๐Ÿ‘ 25    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

itโ€™s a real testament to the intellectual traditions of these centuries-old institutions, folding to authoritarian pressure like paper in a storm and kneeling to naked financial extortion

02.08.2025 03:01 โ€” ๐Ÿ‘ 1300    ๐Ÿ” 342    ๐Ÿ’ฌ 43    ๐Ÿ“Œ 15
A personal message from 2022 chemistry laureate Carolyn Bertozzi to all young researchers on why to aspire to a career in science: 

โ€I would want to share with them how a life in science is incredibly rewarding. It is rewarding because it is creative. You are discovering knowledge and gifting that to humanity for all of posterity. Once you learn something no one can take that away. It is not an object. It is an intellectual currency that will be shared throughout the generations. And you created that. It has a permanence that ironically a physical object doesnโ€™t have. You can paint a painting, but eventually it will fade. But knowledge doesnโ€™t fade. Knowledge stays with us forever and it becomes the foundation for the next generations.โ€

A personal message from 2022 chemistry laureate Carolyn Bertozzi to all young researchers on why to aspire to a career in science: โ€I would want to share with them how a life in science is incredibly rewarding. It is rewarding because it is creative. You are discovering knowledge and gifting that to humanity for all of posterity. Once you learn something no one can take that away. It is not an object. It is an intellectual currency that will be shared throughout the generations. And you created that. It has a permanence that ironically a physical object doesnโ€™t have. You can paint a painting, but eventually it will fade. But knowledge doesnโ€™t fade. Knowledge stays with us forever and it becomes the foundation for the next generations.โ€

A motivating quote from @carolynbertozzi.bskyverified.social:
โ€œโ€ฆYou are discovering knowledge and gifting that to humanity for all of posterity. Once you learn something no one can take that away. It is not an object. It is an intellectual currency that will be shared throughout the generationsโ€ฆโ€

15.07.2025 23:58 โ€” ๐Ÿ‘ 69    ๐Ÿ” 25    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

โ€œThe word โ€˜Dimoreโ€™ in Italian means dwelling but conjures up images of old villas clinging to their aristocratic origins. It lends the name a sense of nostalgia. I think itโ€™s our DNAโ€ โ€“ Britt Moran

No, no, no; a million times no. just stop this. DNA is a polydeoxyribonucleotide.

05.04.2025 13:08 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This part of the Tufts declaration somehow warms my heart the most: a full-throated defense of Rรผmeysa ร–tรผrk's op-ed criticizing the Tufts president, signed by the Tufts president! This is how it's supposed to be!

03.04.2025 13:29 โ€” ๐Ÿ‘ 2605    ๐Ÿ” 586    ๐Ÿ’ฌ 11    ๐Ÿ“Œ 10
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โ€˜I still have nightmaresโ€™: the tourists shackled and jailed for weeks at US borders Visitors suffer hostile treatment since Donald Trumpโ€™s return to the White House

Thinking of going to the US for a meeting?
www.ft.com/content/2197...

30.03.2025 14:02 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Since April, we have been busy curating pathways using GO-CAM pathway modelling. So far, 466 proteins (33 pathways) have been modelled. We have modelled signalling pathways, metabolic pathways, and other processes. The full list is here: www.pombase.org/documentatio..., and will increase weekly!

15.01.2025 13:04 โ€” ๐Ÿ‘ 9    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

you and Martin Taylor were first by a long way.

15.01.2025 19:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

totally bonkers; was it published to show the degree of imbecility amongst the incoming administration?

12.01.2025 14:18 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0