Kellie Machlus's Avatar

Kellie Machlus

@kmachlus.bsky.social

I research hematopoiesis and how megakaryocytes make platelets πŸ©ΈπŸ”¬ Asst Professor at Harvard Medical School and Boston Children’s Hospital πŸ³οΈβ€πŸŒˆ she/her #medsky #scisky #hematology

866 Followers  |  558 Following  |  91 Posts  |  Joined: 25.07.2023  |  2.1165

Latest posts by kmachlus.bsky.social on Bluesky

thanks so much, Vijay!

25.11.2025 20:16 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

thank you, Alejo 🀞

25.11.2025 20:02 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ‘€

25.11.2025 19:11 β€” πŸ‘ 9    πŸ” 0    πŸ’¬ 3    πŸ“Œ 0
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Join us to pursue cutting-edge research at the interface of megakaryocyte biology and translational medicine. We have NIH-funded postdoc positions available to investigate platelet production and the broader functions of megakaryocytes. I’ll be attending ASH and would be happy to connect.

20.11.2025 19:12 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Excited for this session! If you’re at #AHA25 today, please join us!

07.11.2025 15:52 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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A Quiet Policy Shift That Could Devastate American Science Why NIH’s sudden move to multi-year grant funding should alarm every principal investigator and university

A little known - but hugely consequential - part of the government’s changes to science funding:

open.substack.com/pub/sciencea...

29.07.2025 18:06 β€” πŸ‘ 146    πŸ” 83    πŸ’¬ 2    πŸ“Œ 19

So well put. Something I am thinking about every day with research as well.

13.07.2025 16:31 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

becoming a Delta + AMEX whore is the move

12.06.2025 23:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This please πŸ‘‡πŸΌ

05.06.2025 00:35 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Now is a the time to get involved in your scientific societies. #Hematology #HemeSky
@ash.hematology.org is stepping up for Hematology - HOW CAN YOU HELP?

If you want to be on a committee nominate yourself or someone else below. I am also happy to nominate you, so just reach out.
Deadline May 31!

15.05.2025 18:34 β€” πŸ‘ 8    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Congratulations!!!

30.04.2025 21:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Oh.

18.04.2025 22:48 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

😬

07.04.2025 13:12 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Florida debates lifting some child labor laws to fill jobs vacated by undocumented immigrants | CNN Business Florida has been working for years to crack down on employers that hire undocumented immigrants. But that presented a problem for businesses in the state that are desperate for workers to fill low-wag...

This is where we are living.

www.cnn.com/2025/03/25/b...

26.03.2025 02:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

The information I am receiving is consistent with the STAT story.

The boards are being purged of women and minoritized scientists with no other obvious pattern. And for the cases where I have some information, the effects are not subtle...Boards going from 35% women to 10% women.

3/n

25.03.2025 23:01 β€” πŸ‘ 96    πŸ” 80    πŸ’¬ 6    πŸ“Œ 6

πŸ’…

28.02.2025 20:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

same with individuals πŸ‘€

28.02.2025 20:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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FDA cancels meeting to select flu strains for next season's shots The canceled meeting comes just days after a CDC vaccine advisory committee meeting was abruptly postponed.

The FDA just cancelled a meeting to select flu strains for next season's flu shots.

"It's unclear what the canceled meeting will mean for Americans who want to get a flu vaccine next season."

www.nbcnews.com/health/healt...

27.02.2025 02:01 β€” πŸ‘ 291    πŸ” 165    πŸ’¬ 25    πŸ“Œ 53
COALITION OF MAYORS ACROSS U.S. FILE AMICUS BRIEF IN OPPOSITION TO TRUMP ADMINISTRATION’S DRASTIC CUTS TO FEDERAL RESEARCH FUNDING
Led by the City of Boston, MA, City of Cleveland, OH, the Metropolitan Government of Nashville and Davidson County, TN, the Mayor of Gainesville, FL, and the Mayor of Salt Lake City, UT, over 40 mayors, cities, and counties argue that NIH cuts will cause job losses, economic disruption, and undermine U.S. competitiveness

BOSTON - Thursday, February 20, 2025 - Late yesterday, Mayor Michelle Wu co-led a coalition of Mayors from across the United States in writing and filing an amicus brief in federal district court in Boston to stop the Trump Administration's drastic and illegal cuts to federal research funding and immediate job losses in cities nationwide. Over 40 mayors, cities, and counties from across the country joined the brief. These cities are home to universities and hospitals that employ hundreds of thousands of Americans in cutting edge medical and scientific research, and the federally-funded research in these communities has made the United States the global leader in scientific discovery. The brief seeks a temporary restraining order against the Trump Administration, alongside the research universities, medical schools, hospitals, and 22 states that are plaintiffs in the three cases filed last week in federal district court.

β€œFor decades, Congress has made a clear choice to use federally-funded research to invest in cities, build a broadly-distributed infrastructure for scientific discovery, create jobs, and drive economic growth in communities across the United States,” said Mayor Michelle Wu. β€œWe join with cities across the country – in red states, purple states, and blue states – to stop this illegal action that will cause layoffs, lab closures, and undermine scientific progress in American cities. I thank Massachusetts Attorney General Andrea Campbell for her leadership on behalf of the research institutions of Boston.”

COALITION OF MAYORS ACROSS U.S. FILE AMICUS BRIEF IN OPPOSITION TO TRUMP ADMINISTRATION’S DRASTIC CUTS TO FEDERAL RESEARCH FUNDING Led by the City of Boston, MA, City of Cleveland, OH, the Metropolitan Government of Nashville and Davidson County, TN, the Mayor of Gainesville, FL, and the Mayor of Salt Lake City, UT, over 40 mayors, cities, and counties argue that NIH cuts will cause job losses, economic disruption, and undermine U.S. competitiveness BOSTON - Thursday, February 20, 2025 - Late yesterday, Mayor Michelle Wu co-led a coalition of Mayors from across the United States in writing and filing an amicus brief in federal district court in Boston to stop the Trump Administration's drastic and illegal cuts to federal research funding and immediate job losses in cities nationwide. Over 40 mayors, cities, and counties from across the country joined the brief. These cities are home to universities and hospitals that employ hundreds of thousands of Americans in cutting edge medical and scientific research, and the federally-funded research in these communities has made the United States the global leader in scientific discovery. The brief seeks a temporary restraining order against the Trump Administration, alongside the research universities, medical schools, hospitals, and 22 states that are plaintiffs in the three cases filed last week in federal district court. β€œFor decades, Congress has made a clear choice to use federally-funded research to invest in cities, build a broadly-distributed infrastructure for scientific discovery, create jobs, and drive economic growth in communities across the United States,” said Mayor Michelle Wu. β€œWe join with cities across the country – in red states, purple states, and blue states – to stop this illegal action that will cause layoffs, lab closures, and undermine scientific progress in American cities. I thank Massachusetts Attorney General Andrea Campbell for her leadership on behalf of the research institutions of Boston.”

This amicus brief is in response to the abrupt February 7, 2025 announcement by the National Institutes of Health (NIH) of an immediate reduction in funding for scientific and medical research institutions across the country. Under the NIH’s new policy, which temporarily went into effect on Monday, February 10, payments for indirect costs reimbursed to research universities would be capped at 15%, down from 30-70%. The brief makes clear that NIH funding cuts would devastate research institutions in cities across the county, cause job losses, create severe economic disruption, and undermine a critical pillar of strength and civic pride in cities across the United States. The cuts would also undermine critical medical and scientific research that residents are counting on, including cancer, diabetes, and heart disease, and jeopardize the cities’ and country’s position of global leadership on scientific advancement.
β€œThe Gainesville community depends on this highly efficient, dependable investment of our tax dollars back into our city’s innovation economy,” said Harvey L. Ward, Mayor, City of Gainesville, Florida. β€œI’m glad to join other mayors in highlighting the vital role NIH funding plays in the lives of everyday hardworking American families.” 
β€œThe breadth and diversity of this coalition highlights the devastating and widespread impact of these NIH funding changes, from Alzheimer’s research to cancer clinical trials,” said Jill Habig, Founder and CEO of Public Rights Project. β€œWe’re proud to partner with mayors, cities, and counties in opposing this threat to critical federal funding and the health and vitality of our communities.”
On Monday, February 10th, twenty two states and associations of medical schools, hospitals, and universities, filed three related cases, and secured a temporary restraining order preventing the Trump Administration from slashing the reimbursement rates. That initial order will be revisited this week in a hearing scheduled for Feb. 21.

This amicus brief is in response to the abrupt February 7, 2025 announcement by the National Institutes of Health (NIH) of an immediate reduction in funding for scientific and medical research institutions across the country. Under the NIH’s new policy, which temporarily went into effect on Monday, February 10, payments for indirect costs reimbursed to research universities would be capped at 15%, down from 30-70%. The brief makes clear that NIH funding cuts would devastate research institutions in cities across the county, cause job losses, create severe economic disruption, and undermine a critical pillar of strength and civic pride in cities across the United States. The cuts would also undermine critical medical and scientific research that residents are counting on, including cancer, diabetes, and heart disease, and jeopardize the cities’ and country’s position of global leadership on scientific advancement. β€œThe Gainesville community depends on this highly efficient, dependable investment of our tax dollars back into our city’s innovation economy,” said Harvey L. Ward, Mayor, City of Gainesville, Florida. β€œI’m glad to join other mayors in highlighting the vital role NIH funding plays in the lives of everyday hardworking American families.” β€œThe breadth and diversity of this coalition highlights the devastating and widespread impact of these NIH funding changes, from Alzheimer’s research to cancer clinical trials,” said Jill Habig, Founder and CEO of Public Rights Project. β€œWe’re proud to partner with mayors, cities, and counties in opposing this threat to critical federal funding and the health and vitality of our communities.” On Monday, February 10th, twenty two states and associations of medical schools, hospitals, and universities, filed three related cases, and secured a temporary restraining order preventing the Trump Administration from slashing the reimbursement rates. That initial order will be revisited this week in a hearing scheduled for Feb. 21.

The Public Rights Project served as amici counsel. The full list of mayors, cities and counties who joined the brief is below. 



Local Governments and Mayors



City of Boston, Massachusetts
City of Cleveland, Ohio
Harvey L. Ward, Mayor, City of Gainesville, Florida
Metropolitan Government of Nashville and Davidson County, Tennessee
Erin Mendenhall, Mayor, City of Salt Lake City, Utah
City of Alameda, California
City of Albuquerque, New Mexico 
Allegheny County, Pennsylvania
City of Baltimore, Maryland 
Emma Mulvaney-Stanak, Mayor, City of Burlington, Vermont
Township of Canton, Michigan
Town of Chapel Hill, North Carolina
City of Chicago, Illinois 
Sandra Welch, Mayor, City of Coconut Creek, Florida
City of Columbus, Ohio
City of Easthampton, Massachusetts
Daniel Biss, Mayor, City of Evanston, Illinois
City of Fairfax, Virginia
Harris County, Texas
Ravinder S. Bhalla, Mayor, City of Hoboken, New Jersey
Quinton Lucas, Mayor, Kansas City, Missouri
Indya Kincannon, Mayor, City of Knoxville, Tennessee
City of Madison, Wisconsin
Jeff Silvestrini, Mayor, City of Millcreek, Utah
Anissa Welch, Mayor, City of Milton, Wisconsin
Montgomery County, Maryland
City of New Haven, Connecticut
Dontae Payne, Mayor, City of Olympia, Washington 
Adrian O. Mapp, Mayor, City of Plainfield, New Jersey
Sue Noack, Mayor, City of Pleasant Hill, California
City of Pittsburgh and Ed Gainey, Mayor, City of Pittsburgh, Pennsylvania
City of Providence, Rhode Island 
John Clark, Mayor, Town of Ridgway, Colorado
City of Rochester, New York
City of Sacramento, California 
City and County of San Francisco, California
City of Santa Monica, California
Constantine H. Kutteh, Mayor, City of Statesville, North Carolina
Lisa Brown, Mayor, City of Spokane, Washington
Tishaura O. Jones, Mayor, City of St. Louis, Missouri 
City of St. Paul, Minnesota
Dennis R. McBride, Mayor, City of Wauwatosa, Wisconsin

The Public Rights Project served as amici counsel. The full list of mayors, cities and counties who joined the brief is below. Local Governments and Mayors City of Boston, Massachusetts City of Cleveland, Ohio Harvey L. Ward, Mayor, City of Gainesville, Florida Metropolitan Government of Nashville and Davidson County, Tennessee Erin Mendenhall, Mayor, City of Salt Lake City, Utah City of Alameda, California City of Albuquerque, New Mexico Allegheny County, Pennsylvania City of Baltimore, Maryland Emma Mulvaney-Stanak, Mayor, City of Burlington, Vermont Township of Canton, Michigan Town of Chapel Hill, North Carolina City of Chicago, Illinois Sandra Welch, Mayor, City of Coconut Creek, Florida City of Columbus, Ohio City of Easthampton, Massachusetts Daniel Biss, Mayor, City of Evanston, Illinois City of Fairfax, Virginia Harris County, Texas Ravinder S. Bhalla, Mayor, City of Hoboken, New Jersey Quinton Lucas, Mayor, Kansas City, Missouri Indya Kincannon, Mayor, City of Knoxville, Tennessee City of Madison, Wisconsin Jeff Silvestrini, Mayor, City of Millcreek, Utah Anissa Welch, Mayor, City of Milton, Wisconsin Montgomery County, Maryland City of New Haven, Connecticut Dontae Payne, Mayor, City of Olympia, Washington Adrian O. Mapp, Mayor, City of Plainfield, New Jersey Sue Noack, Mayor, City of Pleasant Hill, California City of Pittsburgh and Ed Gainey, Mayor, City of Pittsburgh, Pennsylvania City of Providence, Rhode Island John Clark, Mayor, Town of Ridgway, Colorado City of Rochester, New York City of Sacramento, California City and County of San Francisco, California City of Santa Monica, California Constantine H. Kutteh, Mayor, City of Statesville, North Carolina Lisa Brown, Mayor, City of Spokane, Washington Tishaura O. Jones, Mayor, City of St. Louis, Missouri City of St. Paul, Minnesota Dennis R. McBride, Mayor, City of Wauwatosa, Wisconsin

The City of Boston is leading 40+ mayors, cities, and counties in an amicus brief against the Trump Administration's drastic and illegal cuts to federal research fundingβ€”cuts that will lead to immediate job losses nationwide.

20.02.2025 22:16 β€” πŸ‘ 1482    πŸ” 428    πŸ’¬ 34    πŸ“Œ 80
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Trump Administration Stalls Scientific Research Despite Court Ruling Using an arcane law, officials have effectively delayed funding from the National Institutes of Health, leaving medical studies in jeopardy.

The Trump administration blocked key parts of the federal government’s apparatus for funding biomedical research, effectively halting progress on much of the country’s future work on illnesses like cancer and addiction despite a federal judge’s order to release grant money.

22.02.2025 06:25 β€” πŸ‘ 1196    πŸ” 544    πŸ’¬ 115    πŸ“Œ 36
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5 Calls Spend 5 minutes. Make 5 calls. Make your voice heard.

Ok scientists & those who love science πŸ§ͺ: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at:
5calls.org

21.02.2025 17:23 β€” πŸ‘ 108    πŸ” 88    πŸ’¬ 5    πŸ“Œ 8
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Revealed: NIH research grants still frozen despite lawsuits challenging Trump order The Trump administration is exploiting a loophole to keep a funding freeze in place, leaving researchers in limbo.

Almost all grant-review meetings under Trump 2.0 remain suspended at the US National Institutes of Health (NIH), preventing the world’s largest public funder of biomedical research from spending much of its US$47 billion annual budget.


https://go.nature.com/4gM6oW4


20.02.2025 20:04 β€” πŸ‘ 292    πŸ” 238    πŸ’¬ 8    πŸ“Œ 21

Is there an open access link to share?

20.02.2025 16:50 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is a red alert for US science, for new cures & treatments for diseases that afflict everyone in this country. This isn't "oh, it will blow over." Soon we will have reached the point of no return destroying what it has taken decades to build. WE NEED TO BE BANGING DOWN THE DOORS IN CONGRESS.

20.02.2025 15:33 β€” πŸ‘ 159    πŸ” 89    πŸ’¬ 4    πŸ“Œ 2

Study section freeze hits NIH

19.02.2025 18:34 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Federal Register hold makes β€˜end run’ around court pause on NIH funding freeze NIH-related updates to the Federal Register, which are required for the scheduling of study sections and advisory councils, are on hold indefinitely, according to an email reviewed by <i>The Transmitt...

A large portion of grants awarded by the U.S. National Institutes of Health cannot be funded for the foreseeable future because of an indefinite hold on submissions to the Federal Register, according to an email reviewed by The Transmitter.

By @avaskham.bsky.social

bit.ly/3X8ngz8

18.02.2025 23:22 β€” πŸ‘ 352    πŸ” 331    πŸ’¬ 12    πŸ“Œ 48

\same!

16.02.2025 18:23 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Current inspiration as I continue doing my science as a form of protest and resistance. πŸ§ͺ🩸πŸ’ͺ

16.02.2025 01:46 β€” πŸ‘ 23    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Obviously that was my position too πŸ’ͺ🏼

14.02.2025 13:05 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

You’re the one who literally posted that you don’t care about what’s happening.
If you don’t want to send that message, don’t post it. It is taken at face value.

10.02.2025 01:47 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 3    πŸ“Œ 0

@kmachlus is following 20 prominent accounts