Transplant Operative Assessment Tool offers structured feedback for surgical trainees—evaluating anatomy, technique, judgment & communication. 82 cases— strong reliability (α=0.94) clearly distinguished trainee levels—advancing competency-based training tinyurl.com/bddz24j7

New global study of 2,600 living liver donors!
Robotic hepatectomy outperformed open & laparoscopic surgery — showing:
🩸 Less blood loss
💊 Lower pain
🏥 Shorter hospital stays
⚕️ Fewer complications. #TXPforAll #LiverTransplantation #TransplantTwitter
tinyurl.com/2tuxzfaz

This study shows that liver transplants from ECMO-DCD donors using normothermic regional perfusion (NRP) are feasible — with good graft function and recovery — but require careful planning for optimal outcomes. #TXPforAll #Transplantation #OpenAccess tinyurl.com/375vwsv3

Chui et al. showed that MMR infections were extremely rare in over 313,000 solid organ transplant recipients. None occurred in individuals who were vaccinated before receiving a transplant, which highlights the importance of pretransplant MMR vaccination tinyurl.com/yc3v97kj

Freely downloadable paper introduces Australian Matchability Score (M-score), quantifying how HLA profiles affect kidney transplant access. Higher M-scores (harder to match) were linked to lower transplant likelihood and higher graft loss & rejection risk tinyurl.com/r8ntxtwx

For patients with alcohol-associated liver disease, pursuing living donor liver transplantation reduces waitlist dropout due to death or deterioration, with comparable survival to deceased donor LT. #TXPforAll #MedTwitter #LiverTransplantation tinyurl.com/2s3jn5zs

Adjustable Graft Failure Score (AdGFS) accurately predicts kidney graft loss using 1-year data. In >1,200 patients, 10-year survival fell from 89% to 23% across risk groups—supporting AdGFS as a tool for tailored care and clinical trial design. #TXPforAll tinyurl.com/4ckkanu8

#TBT to this week's featured top downloaded paper from 2022:Shiraz, Iran: The Largest Center for Pancreas Transplantation in the Middle East #Transplantation #Med tinyurl.com/mrypaysd

Freely downloadable paper shows biomarker dynamics vary between hypothermic (HMPO₂) and normothermic (NMP) perfusion in kidney transplants. Some biomarkers align across methods, but NMP provides key insights into function and reconditioning potential tinyurl.com/35tdhj2s

Study of >15 years of liver transplants shows ➡Severe obesity (BMI ≥40) increases graft loss & mortality in patients with low performance status, but not in those who are fitter. Performance before surgery makes all the difference. #TXPforAll tinyurl.com/yc3y6ye5

New hope for heart transplants! The HOPE device preserved DCD donor hearts for ~298 min in 5 North American patients with severe heart failure. Most had strong recoveries—one death unrelated to the heart. Promising results, but more studies needed tinyurl.com/yz34sfj4

Turning “inoperable” into “transplantable.” Using immune checkpoint inhibitors before liver transplant helped downstage advanced HCC—4 complete responses & 75% survival at 2 years. Early promise. #TXPforAll #LiverTransplantation #OpenAccess tinyurl.com/58bz3raz

Higher-dose TNX-1500 improved kidney xenotransplant survival (pig→baboon) but caused severe proteinuria, leading to drug loss & higher rejection risk. Next challenge: stop protein loss to boost graft success. #Xenotransplantation #TXPforAll @harvardmed tinyurl.com/47vmhah7

Across 10 European transplant centers, biopsy-based transcriptomics (BBT) use and indications vary widely. Moderate agreement with histology (κ=0.49) highlights the need for standardized integration into kidney transplant diagnostics. #TXPforAll #Kidney tinyurl.com/mub6m4dm

Frailty and sarcopenia double mortality in liver transplant candidates and impair recovery. Early detection, nutritional optimization, and personalized (p)rehabilitation are essential to improve outcomes. @BirminghamBRC #TXPforAll #LiverTransplantation tinyurl.com/4u4rr689

🫁 Byers et al. investigated whether lung function decline can predict survival after lung transplantation. 🫁#LungTransplantation #TXPforAll tinyurl.com/y9x64ttv

Inflammation continues to shorten transplant survival. 🧠💉This freely downloadable review paper discusses whether vagus nerve stimulation, which harnesses the body’s own anti-inflammatory reflex, can help protect grafts and improve outcomes. #TXPforAll tinyurl.com/b94k3nvb

BK polyomavirus in kidney transplant recipients: BKPyV QNAT reliably rules out BKVAN when negative, but positive results cannot distinguish true tissue-invasive infection. #TXPforAll #OpenAccess #Kidneytransplantation tinyurl.com/32kjdyvh

Extracorporeal photopheresis may prevent trained immunity and promote transplant tolerance, offering a potential new prophylactic strategy. #TXPforAll #OpenAccess #immunology tinyurl.com/ytccs2dv

In kidney transplant recipients, sotagliflozin (SGLT1/2 inhibitor) caused an initial eGFR dip—but changes were largely reversible after withdrawal.
🔹Well tolerated overall
🔹Adherence unaffected by eGFR reporting strategy
Promising safety signal for KTRs tinyurl.com/mv9p49k3

#TBT to this week's featured top downloaded paper from 2022: Quality Metrics in Solid Organ Transplantation
A Systematic Review #Transplantation #Med tinyurl.com/yynbnvb8

Top #Transplantation articles this month!
🔹 EVs for noninvasive heart rejection monitoring
🔹 Pregnancy after organ transplant: new guidance
🔹 Kidney care in heart transplant patients
🔹 Donor cfDNA in pediatric kidney rejection

journals.lww.com/transplantjo...

The bioinformatic tool HLA-EP-RESOLVER accurately predicts antibody reactivity to rare HLA alleles using eplet analysis. Validated in sensitized patients, it helps identify acceptable/unacceptable antigens in the era of high-resolution donor typing. #HLA tinyurl.com/2m9nm6ek

Few upper extremity transplants are done worldwide, leaving patients with tough choices. This study shows how hopes, pressures, and quality-of-life concerns shape decision-making—and why better informed consent is key. #TXPforAll @DrMaceyLevan tinyurl.com/5b4rwj6a

Brain death triggers early complement activation in donor kidneys. High complement levels correlated with delayed graft function—highlighting a key target to improve outcomes. #TXPforAll #Transplantation #immunology #OpenAccess tinyurl.com/mvysuzk2

This new tool makes kidney allocation policy design faster—cutting simulation time from 6 hours to just 15 seconds. Faster models mean fairer, smarter decisions for patients waiting on a transplant. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4ykbarrs

#TBT to this week's featured top downloaded paper from 2022: URINARY TRACT INFECTIONS IN RENAL TRANSPLANT RECIPIENTS IN THREE YEARS Recipients #Transplantation #Med tinyurl.com/4mpn66a9

Not all antibody tests agree: this study shows big differences between commercial assays for non-HLA antibodies in kidney transplant rejection. Standardization is urgently needed to clarify their role in AMR and graft loss. #TXPforAll #Transplantation tinyurl.com/c6s5mtk7

Undetected donor infections remain a concern in transplantation. Model shows the critical care interval before screening lowers residual risk—cutting it by ~44% for HCV, 23% for HIV, and 7% for HBV—supporting testing donors. @UniMelb tinyurl.com/4v9r9her

BK virus is a major cause of kidney transplant failure. This study shows that boosting virus-fighting immune cells in the lab—and adding checkpoint inhibitors—could make future treatments more effective at protecting transplanted kidneys. #TXPforAll tinyurl.com/5n76fk77