Christoph Rademacher

Interested in glycan-binding proteins in Immunity? Check out this review with Gabriel Rabinovich, @chrrademacher.bsky.social, and Mirta Schattner on this subject.
www.annualreviews.org/docserver/fu...

Covalent Activation of the C‐type Lectin DC‐SIGN We introduce the first covalent activators of a C-type lectin. Using orthogonal functional assays, NMR, MS/MS, and computational modeling, we delineate mechanisms from a functional electrophile-first...

Surprising discovery of a covalent activator of a C-type lectin!
We identified the first covalent small-molecule activators of the human C-type lectin DC-SIGN.
Instead of inhibiting glycan binding, two warheads increased DC-SIGN activity.

Open access here:
doi.org/10.1002/anie...

Targeted Drug Delivery ermöglicht zielsichere Medikamente Mit Targeted Drug Delivery werden Immunzellen in der Haut gezielt angesteuert – so minimieren der Molekularbiologe Christoph Rademacher und sein Team Nebenwirkungen. Das eröffnet neue Therapieoptionen...

Mittels Targeted Delivery können #Medikamente direkt am Bestimmungsort wirken. Ein Forschungsteam @univie.ac.at hat eine Methode entwickelt, mit der Immunzellen in der Haut zielsicher angesteuert werden können. @chrrademacher.bsky.social #scilog 💊

scilog.fwf.ac.at/magazin/ziel...

Confronting risks of mirror life Broad discussion is needed to chart a path forward

Thanks to Ratmir Derdra, our #glycotime answer to "The risk of mirror life" appears now under the article in Science www.science.org/doi/10.1126/...
With @glycoexpasy.bsky.social @laurakiessling.bsky.social @carolynbertozzi.bskyverified.social @molinarotony.bsky.social @dbojar.bsky.social
and many

and more... @glycosmos.bsky.social @glycocode.bsky.social @chrrademacher.bsky.social @ethangbaus.bsky.social and again more but bluesky handle found
@glyconet.bsky.social @sib.swiss

Confronting risks of mirror life Broad discussion is needed to chart a path forward

Thanks to Ratmir Derda we have an articulate reply to:
www.science.org/doi/10.1126/...
putting glycans back into the picture! @laurakiessling.bsky.social @anneimb.bsky.social @carolynbertozzi.bskyverified.social @molinarotony.bsky.social @dbojar.bsky.social @siglecdude.bsky.social

We are hiring, please RT! #Postdoc in the @ERC_Research project #DORMATRIX, developing #advanced #3Dimaging of #cancer dormancy & #metastasis. Bioengineers, biophysicists, biologists, computer scientists or similar. @biogipuzkoa @Ikerbasque. More info👉 bit.ly/4gXLP96

Join the Molecular Drug Targeting Lab at the University of Vienna!
I have a vacant postdoc position for a qualified candidate: either with a background in delivery technologies or immunology.

jobs.univie.ac.at/job/Universi...

Hello, Bluesky community! Let our first post be a good news: CBDD researchers Geert-Jan Boons and Rob de Vries (@rpdevrieslab.bsky.social), together with researchers in ErasmusMC Rotterdam, were awarded an #ENW-XL from the Dutch Research Council. Stay tuned for #phd/#post-doc openings! #glycotime

Here is a brief summary of academic journals and news account.

Please help me add more accounts to this list!

go.bsky.app/hCfhqn

Congratulations!

That was an exciting meeting ! Thanks for the invite and the fantastic organization

It was a great privilege to chair the ChemBio VII conference (www.chembiovii.es) held in Seville. The organizing committee worked very hard to make the meeting a success. Amazing contributions and discussions in Chemical Biology with colleagues, with the beautiful Seville as a backdrop.

Glycotime Join the conversation

🧬🧶 people, if you're interested in knowing a bit more about the molecules that your proteins simply act as scaffolding for, check out or starter packs and lists. go.bsky.app/QTL6EqT

Still time to register to awsome Glycobiology Gordon Research Conference 2025. We have a fantastic line of speakers and this will be top #glycotime in Tuscany !! Register at www.grc.org/glycobiology...