Chris Carnie

🧬🧬🧬 REGISTRATION JUST OPENED! Make sure you join our DNA REPAIR MEETING 2026 ON PHYSIOLOGICAL CAUSES AND CONSEQUENCES OF GENOME INSTABILITY in Cologne, September 7-9, organized by the German Society for DNA Repair (DGDR) and the @dfg.de Research Unit 5504. www.for-5504.com/en/197/Confe...

Great to see this team effort out, in which we find a new player in genome stability and a neurodevelopmental disease caused by its loss. Fantastic collaboration with @drjhujh.bsky.social and @profstewartlab.bsky.social alongside @sorenhough.bsky.social and friends in @spjacksongroup.bsky.social.

Nice work Pia, Ross and team!

Brian Huntly and I are looking to recruit a postdoc to investigate a promising novel therapeutic target in B-ALL @scicambridge.bsky.social. This new CRUK-funded project will involve collaboration with Prof Sir Steve Jackson's group @cruk-ci.bsky.social and the CRUK Functional Genomics centre.

Really cool work from our KiTZ colleagues!

Congrats Román!

Now peer reviewed and in its final form @natcomms.nature.com

www.nature.com/articles/s41...

Postdoctoral Research Associate in the Blackford Group A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th

We’re #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms.

Please get in touch with your CV if you are interested; closing date: 27th June 2025.

More details here: candidate.hr-manager.net/ApplicationI...

Reminds me of a line in Hannibal: ‘Trade? How does that word taste to you, Clarice? Cheap and metallic, like sucking on a greasy coin?’

🚨 Check out our latest review in #MolecularCell!

We discuss how formaldehyde, a toxic metabolic by-product, threatens genome stability and disrupts cellular homeostasis.

👏 Outstanding work by our talented PhD Std #MartaValverde @carrerasijc.bsky.social

👉📰
authors.elsevier.com/a/1lDFm3vVUP...

Multigenerational cell tracking of DNA replication and heritable DNA damage - Nature A multigenerational single-cell tracking approach provides a framework to dissect phenotypic plasticity at the single-cell level, offering insights into cellular processes that may resemble early even...

Delighted to share that the results of my main postdoc project are now published in @nature.com

🔗 doi.org/10.1038/s415...

Cool, looking forward to reading this! Congratulations alln

A PhD position is open in my group here in Heidelberg. We'll use cool primary cell models of osteosarcoma and genetic screens to understand and overcome mechanisms of clinically acquired drug resistance. It'll be a blast!

karriere.klinikum.uni-heidelberg.de/index.php?ac...

There’s something fishy about this plot

Exciting opportunity for a suitably qualified individual to join us, www.jobs.cam.ac.uk/job/50998/

Nuclear and genome dynamics underlying DNA double-strand break repair Nature Reviews Molecular Cell Biology - Changes in nuclear and genome organization promote the repair of DNA double-strand breaks and genome stability. Processes that are involved include the...

🚀 New Paper Alert! Our latest @natrevmcb.bsky.social explores how nuclear and genome organization drive DNA double-strand break repair! 🧬

📖 Free access: rdcu.be/edViW

Please 🔄 ❤️

Cellular responses to RNA damage RNA plays a central role in protein biosynthesis and performs diverse regulatory and catalytic functions, making it essential for all processes of life. Like DNA, RNA is constantly subjected to damage...

Happy to share our review on the cellular responses to RNA damage 🥂

Congrats to joined first authors Jacqueline Cordes & @shubozhao.bsky.social

www.cell.com/cell/fulltex...

Dear all,

Postdoc positions are available to work on (1) the role of DNA strand break repair proteins during DNA replication and (2) the molecular/structural biology of XRCC1 protein complexes, as part of our work on genetic diseases & cancer. Contact me if interested: k.w.caldecott@sussex.ac.uk

Dear all, my first post! I have postdoc positions available if you would like to join my lab in beautiful Sussex by the Sea! Please contact me on k.w.caldecott@sussex.ac.uk

It’s a cynical ploy to make you buy their UBE2T aftersun

As a side note: kudos to the many people who gave us the nice flood of STK19 papers that were published just in time for us to cite the final articles rather than the preprints!

Big thanks to Ilaria Carnevale, the team at Trends in Cell Biology, and to the reviewers for their constructive input.

Transcription-coupled repair of DNA–protein crosslinks DNA–protein crosslinks (DPCs) are highly toxic DNA lesions that are relevant to multiple human diseases. They are caused by various endogenous and environmental agents, and from the actions of enzymes...

Happy to share a review written with the wonderful @jstingele.bsky.social on transcription-coupled DPC repair, featuring an overview of new methods, close comparison with TC-NER, comments on clinical implications and plenty of discussion of the unknowns.

www.cell.com/trends/cell-...

I'd hope that they're only showing the awardees once as 7/800 is even worse that 13! But yes, confusing representation...

Must be cumulative? Still, 13/800 is also pretty grim.

Happy to share our latest work🍾 🥳

PhD student Sophie Dürauer discovered together with many wonderful collaborators that the ubiquitylation of DNA-protein crosslinks promotes their cleavage by SPRTN more than 100-fold 🧬🔧

I'd venture an 'an excitation'

Your chance to join one of the best labs in the field!

Great supervisor, great project

Sadly, I'm too old

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

www.embl.org/about/info/c... might be a good addition