Caleigh Findley, PhD

SSRIs Restore Brain Function in Alzheimer’s - Neuroscience News A new study suggests that SSRIs, commonly prescribed antidepressants, may reduce biological markers of Alzheimer’s disease.

Interesting findings that may inform us about disease-specific regulatory mechanisms involving serotonin #SSRI #Alzheimers neurosciencenews.com/ssris-alzhei...

#science TRUCKS for the BRAIN...
Scientists develop gene delivery ‘trucks’
Gene delivery systems can target specific brain cells, a breakthrough that could lead to treatments for #Parkinson's, #Alzheimer's and other #neurodegenerative diseases.
www.washingtonpost.com/science/2025...

Find the hero energy in the story of your research Want to connect with funders, the media, the public or policymakers? Start by thinking like a storyteller

As a #researcher, do you want to connect with funders, the media, the public or policymakers? Start by thinking like a storyteller, writes Erin O'Dwyer of @sydney.edu.au: ow.ly/HpfS50VZ2WV #research #academicsky #impact #scicomm

The great brain clearance and dementia debate An established theory for how good sleep reduces a person’s risk of neurodegenerative disease has been called into question. The ensuing argument could have enormous consequences for the treatment of Alzheimer’s disease.

A Nature Outlook feature reports on the questions around an established theory for how good sleep reduces a person’s risk of neurodegenerative disease and how the debate could have enormous consequences for the treatment of Alzheimer’s disease. #medsky #alzsky 🧪

An Expensive Alzheimer’s Lifestyle Plan Offers False Hope, Experts Say Thousands of people have paid for Dale Bredesen’s unconventional program to reverse Alzheimer’s symptoms. The medical establishment says there’s little to no proof it works.

Thousands of people have paid for Dale Bredesen’s unconventional program to reverse #Alzheimers symptoms. The medical establishment says there’s little to no proof it works. #dementia

17 simple ways to lower your risk of stroke, dementia and depression all at once | BBC Science Focus Magazine Think of this like a menu for a long, healthy and happy life

🧠 17 simple ways to lower your risk of #stroke, #dementia and #depression all at once.

#Health

www.sciencefocus.com/news/17-risk...

Basic science, exceptional outcomes: A look at how non-clinical research is an important investment into human health Basic research, intended to better our understanding of the world rather than directly investigate diseases, has laid the groundwork for some of the most important developments in modern medicine. …

There's no doubt about it, curiosity-driven research is important.

This week, @joulesriley.bsky.social shares how years of curiosity-driven research led to two of the biggest clinical breakthroughs of the modern era: pennneuroknow.com/2025/05/20/b...

#neuroskyence #PsychSciSky #SciComm 🧪

Where AI Adds Real Value in Clinical Development While Quantum computing has been reported to be five years away for many years now, companies are preparing for it by setting foundations with AI in development.

Today is #ClinicalTrialsDay, a perfect time to ask:

Where is #AI best used in clinical trials? And what should sponsors be doing now to get quantum ready?

Learn more ⬇️

www.biospace.com/drug-develop...

Harnessing the power of lifestyle interventions to combat biological aging: Insights from the DO-HEALTH trial

Harnessing the power of lifestyle interventions to combat biological aging: Insights from the DO-HEALTH trial. #TIC2025

Open Access
www.the-innovation.org/article/doi/...

Overwork and changes in brain structure: a pilot study Objectives To investigate the effects of overwork on brain structure to better understand its impact on workers’ cognitive and emotional health. The goal was to provide evidence for the potential neur...

🧠⏰ Do long hours of work change our brains?

A new study finds overwork may alter brain regions linked to thinking and emotions – raising concerns for worker health.

🔗 oem.bmj.com/content/earl...

#SciComm #BrainHealth #Work 🧪

Affordable Blood Test Detects Early Alzheimer's Signs at Lower Cost Keck School of Medicine of USC researchers have developed a blood test that could change how we screen for Alzheimer's disease years before symptoms

scienceblog.com/affordable-b... @keckschoolusc.bsky.social #alzheimers

Environmental Pollution Can Increase Your Alzheimer’s Risk, Say BrightFocus-Funded Scientists Urban and rural communities alike face potential long-term health consequences from environmental toxins that could lead to Alzheimer’s disease.

What does air pollution have to do with Alzheimer’s disease? More than most people realize.

A healthier environment promotes healthier aging. Read more: www.brightfocus.org/resource/env...

#alzsky

How your genes interact with your environment changes your disease risk − new research counts the ways Environmental factors such as lifestyle and the medications you take influence the effects your genes have on your body − and can clarify how diseases develop.

🧪 This is a great #scicomm explainer of a fascinating and extremely complex subject. Links to papers available

theconversation.com/how-your-gen...

Male mice prefer to live on their own www.biorxiv.org/content/10.1... "Hell is other mice" - Mouse Sartre

Bright blue lines connect at nodes, set against a black background.

"Governance should not be understood as an impediment to AI innovation but as an essential component of it." A new article in the National Academy of Engineering's The Bridge from @alondra.bsky.social discusses the value of policy and governance for AI systems. Read now: buff.ly/sFRy6qW

Glucagon‐like peptide‐1 analogues reduce alcohol intake Click on the article title to read more.

🍷 Weight-loss meds may help cut drinking

A new study found people taking semaglutide or liraglutide drank less alcohol – and no one drank more.

These meds might support people with both weight and alcohol issues.

🔗 dom-pubs.onlinelibrary.wiley.com/doi/10.1111/...

#SciComm #Alcohol #Obesity 🧪

Could this breakthrough research lead to the first treatment for #longCOVID? A world-first milestone made possible through the advanced technologies of the National Drug Discovery Centre.

Find out more: www.wehi.edu.au/news/tacklin...

Scientists Discover Hidden Cause of Alzheimer’s Hiding in Plain Sight Researchers found the PHGDH gene directly causes Alzheimer’s and discovered a drug-like molecule, NCT-503, that may help treat the disease early by targeting the gene’s hidden function. A recent study...

#alzheimers
#UCSD
#weneedscience
#curesarecoming

scitechdaily.com/scientists-d...

Confocal microscopy photo

Astrocytes🔵 reacting to B-amyloid🟣 accumulation in the Human Neocortex. One of the hallmarks of #Alzheimers and other neurodegenerative conditions. What if viral infections increase the accumulation of these and other misfolded proteins in the brain? 🤔🔬 #FluorescenceFriday

Alchemab and Lilly ink $415m neurodegeneration drug licensing deal Drug based on naturally occurring protective antibody has demonstrated a neuroprotective role in multiple neurodegenerative conditions.

Alchemab and Lilly ink $415m neurodegeneration drug licensing deal
Drug based on naturally occurring protective antibody has demonstrated a neuroprotective role in multiple neurodegenerative conditions.
#longevity #biotech #pharma #neurodegeneration

The Molecular Bond That Helps Secure Your Memories | Quanta Magazine How do memories last a lifetime when the molecules that form them turn over within days, weeks or months? An interaction between two proteins points to a molecular basis for memory.

How do memories last a lifetime when the molecules that form them turn over within days, weeks or months? An interaction between two proteins points to a molecular basis for memory. @ajdinahalilovic.bsky.social reports: www.quantamagazine.org/the-molecula...

Need a coping strategy in the face of *waves arms around*? After seeing more misinformation accounts here, I've been doing a dive on #scicomm best practices. We scientists should triple down on this and dial up our prebunking and debunking efforts. Here's a 🧵 of strategies and resources: 🧪

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Interviewing Scientist Sources - The Open Notebook Although interviewing a scientist isn’t much different than interviewing any other source, their professional norms likely differ from yours. Understanding where scientists are coming from can help yo...

Interviewing a scientist isn’t much different than interviewing any other source, but understanding where scientists are coming from can help you conduct smooth interviews and maintain great relationships with your sources. Here’s a quick guide for success. 🧪

NIH Activities Grind to Halt Under Trump Comms Freeze The Trump administration locks down the U.S. NIH, interrupting medical research and drug development. Scientists sound the alarms.

NIH activities grind to a halt. For Being Patient, I wrote about how this impacts #Alzheimer's research and clinical trials.

Thanks to @suzanneeschindler.bsky.social and Sheeva Azma for comment.

www.beingpatient.com/nih-grinds-t...

Thank you!!

New to Bluesky 👋 where are my #scicomm and #neuro people at?

People actually believe that Vivek "cured Alzheimer's?"

🤣🤣🤣🤣🤣🤣🤣🤣🤣🤣🤣

GLP-1 agonists being a good treatment for schizophrenia is so freaking weird.

Scientific advancements aside, this is economically irresponsible

Every $1 spent by NIH generates $2.46

For example, in 2023, $47B in NIH spending generated ~$93B

Halting NIH spending will LOSE the US a lot of money (and talent)