André Katayama Yamada

Endurance training promotes chromatin closure and timely repression of the post-exercise immediate early stress response Endurance training is known to elicit numerous changes in skeletal muscle to enhance performance and function. Many of these adaptations are controlle…

"Endurance training promotes chromatin closure and timely repression of the post-exercise immediate early stress response" - our new manuscript describes the changes in chromatin accessibility in exercise (acute & training) associated with gene expression.
www.sciencedirect.com/science/arti...

Scientists discover unique molecular fingerprints of insulin resistance Scientists have unearthed surprising details about how our bodies handle insulin – the hormone that plays a crucial role in regulating blood sugar and developing diabetes.

Highlighting our latest research.
Deconvoluting insulin signaling in human skeletal muscle.
www.news-medical.net/news/2025052...

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Transparent mice made with light-absorbing dye reveal organs at work A method that renders skin temporarily see-through could offer researchers a non-invasive way to look inside the bodies of live mice.

Transparent mice made with light-absorbing dye reveal organs at work

Myospreader improves gene editing in skeletal muscle by myonuclear propagation https://www.biorxiv.org/content/10.1101/2023.11.06.565807v1 Successful CRISPR/Cas9-based gene editing in skeletal muscle is dependent on efficient propagation o

Myospreader improves gene editing in skeletal muscle by myonuclear propagation https://www.biorxiv.org/content/10.1101/2023.11.06.565807v1

Molecular Landscape of Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-OMICs Integration https://www.biorxiv.org/content/10.1101/2024.07.14.603458v1 We conducted a large-scale, statistically powered, meta-analysis of exercise adaptations in human sk

Molecular Landscape of Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-OMICs Integration https://www.biorxiv.org/content/10.1101/2024.07.14.603458v1