People often talk about the time critical nature of sepsis. But it may surprise you to hear that the evidence to support “early” antibiotics actually isn't a settled debate. Why is that? The key question is “early in relation to what”? 🧵 1/n
03.12.2024 09:38 — 👍 64 🔁 30 💬 4 📌 3
A sad day for critical care - and what a phenomenal legacy he has left us.
RIP Prof Gattinoni, a Giant ⚕️📟
www.esicm.org/obituary-luc...
Hello all! On behalf of the editors, @maxhockstein.bsky.social and @zentensivist.bsky.social, we’d like to announce the launch of our living textbook for hemodynamics, shockwaves.icu! #emimcc
18.11.2024 14:16 — 👍 26 🔁 11 💬 3 📌 3
Rant #5 Please don't tell me what the PaO2 is...
Less experienced critical care staff members are frequently exercised by arterial blood gas PaO2 readings.
What is the SpO2 I genially ask? In our target range? Well that's fine then.
Staff member shifting uneasily, "but the PaO2..."
Here we go...
#PCCSky Update
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Working on a nice article about this!
22.11.2024 14:14 — 👍 0 🔁 0 💬 0 📌 0
Sprinkling some minaralocorticoid.
#emimcc
Steroid in sepsis.
Should hydrocortisone be supported by fludrocortisone?
Three behemoths of critical care say we need more dedicated RCTs…
esicm.us1.list-manage.com/track/click?...
#PCCMSky Update
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I am really happy with this conceptual study - pure vasoconstriction can improve cardiac output if you increase stressed volume and the heart is preload dependent. We induced preload dependency by HUT and vasoconstricted with phenylephrine.
pmc.ncbi.nlm.nih.gov/articles/PMC...
Honey, stop what you're doing, new hyponatremia research just dropped!
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
Not new but interesting evidence on huge topic! To have it around.
evidence.nejm.org/doi/full/10....
It’s almost here! Join us for an exciting online course on hemodynamics—perfect for ICU physiology geeks! Featuring top researchers and excellent clinicians. Don’t miss out!
16.11.2024 12:58 — 👍 3 🔁 0 💬 0 📌 0