People often talk about the time critical nature of sepsis. But it may surprise you to hear that the evidence to support “early” antibiotics actually isn't a settled debate. Why is that? The key question is “early in relation to what”? 🧵 1/n
03.12.2024 09:38 — 👍 63 🔁 30 💬 4 📌 3
Obituary: Luciano Gattinoni - ESICM
In Memory of Professor Luciano Gattinoni
A sad day for critical care - and what a phenomenal legacy he has left us.
RIP Prof Gattinoni, a Giant ⚕️📟
www.esicm.org/obituary-luc...
02.12.2024 17:02 — 👍 80 🔁 32 💬 7 📌 5
Rant #5 Please don't tell me what the PaO2 is...
Less experienced critical care staff members are frequently exercised by arterial blood gas PaO2 readings.
What is the SpO2 I genially ask? In our target range? Well that's fine then.
Staff member shifting uneasily, "but the PaO2..."
Here we go...
25.11.2024 21:15 — 👍 63 🔁 20 💬 9 📌 9
#PCCSky Update
122 members
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25.11.2024 13:37 — 👍 18 🔁 13 💬 5 📌 0
Working on a nice article about this!
22.11.2024 14:14 — 👍 0 🔁 0 💬 0 📌 0
Sprinkling some minaralocorticoid.
#emimcc
Steroid in sepsis.
Should hydrocortisone be supported by fludrocortisone?
Three behemoths of critical care say we need more dedicated RCTs…
esicm.us1.list-manage.com/track/click?...
22.11.2024 13:34 — 👍 12 🔁 6 💬 4 📌 0
#PCCMSky Update
Up to 95 members
Repost so those new to this place can populate their following list with good PCCM people
Reply if you are not on this list and should be
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21.11.2024 13:49 — 👍 58 🔁 33 💬 17 📌 0
I am really happy with this conceptual study - pure vasoconstriction can improve cardiac output if you increase stressed volume and the heart is preload dependent. We induced preload dependency by HUT and vasoconstricted with phenylephrine.
pmc.ncbi.nlm.nih.gov/articles/PMC...
18.11.2024 11:28 — 👍 16 🔁 5 💬 3 📌 1
Correction Rates and Clinical Outcomes in Hospitalized Adults With Severe Hyponatremia
This systematic review and meta-analysis evaluates the association of sodium correction rates with mortality among hospitalized adults with severe hyponatremia.
Honey, stop what you're doing, new hyponatremia research just dropped!
What's it say?
It looks like slow correction is associated with worse outcomes, like death and length of stay!
Was it just a small study?
No, it was a meta-analysis of almost 12,000 patients!
jamanetwork.com/journals/jam...
19.11.2024 04:51 — 👍 337 🔁 133 💬 46 📌 33
It’s almost here! Join us for an exciting online course on hemodynamics—perfect for ICU physiology geeks! Featuring top researchers and excellent clinicians. Don’t miss out!
16.11.2024 12:58 — 👍 3 🔁 0 💬 0 📌 0
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