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Sarah Merkling

@merklinglab.bsky.social

We are all about mosquitoes, viruses and single cells! Insect Infection and Immunity - Merkling Lab @CNRS.fr @Pasteur.fr @ERC.europa.eu #newPI #DiversityEquityInclusion #ally ๐Ÿณ๏ธโ€๐ŸŒˆ๐Ÿณ๏ธโ€โšง๏ธ https://aedes-cell-atlas.pasteur.cloud/

1,451 Followers  |  1,395 Following  |  53 Posts  |  Joined: 25.10.2023  |  2.3721

Latest posts by merklinglab.bsky.social on Bluesky

Still looking for our perfect doctoral candidate as part of @evomg-dn.bsky.social - come and join us to work on the evolutionary pressures that shape gene expression and disease in the uterus!

Please RT (or is it RB? not sure how our lingo has changed!)

14.11.2025 10:22 โ€” ๐Ÿ‘ 16    ๐Ÿ” 24    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Sarah Merkling wants to "pasteurize" mosquitoes! At the Institut Pasteur, Sarah Merkling's research focuses on a topic that is still largely unknown: interactions between mosquitoes and viruses. She boldly devises novel strategies based on state-of-...

๐ŸฆŸ Can we "pasteurize" mosquitoes to stop dengue & Zika?

Sarah Merkling @merklinglab.bsky.social uses AI + CRISPR to analyze stomach cells and understand why some mosquitoes spread viruses while others don't.

Goal: Make disease-carrying mosquitoes harmless.
#Zika #Dengue

12.11.2025 08:50 โ€” ๐Ÿ‘ 30    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ‘ฉโ€๐Ÿ”ฌJ'ai commencรฉ un kit de dรฉmarrage "chercheuses en France" go.bsky.app/TBEzKC #FemmesEnScience

J'ai besoin de votre aide pour le remplir et donner de la visibilitรฉ aux chercheuses que vous connaissez et qui sont sur Bluesky !
โ–ถ๏ธTaguez celles que vous connaissez, je les ajoute !

23.09.2025 14:22 โ€” ๐Ÿ‘ 349    ๐Ÿ” 235    ๐Ÿ’ฌ 75    ๐Ÿ“Œ 11

Virology lost one of his monuments, David Baltimore. To learn more about him and his contributions, I recommend (re)-listening to this great TWIV episode : www.microbe.tv/twiv/twiv-10...

08.09.2025 12:58 โ€” ๐Ÿ‘ 6    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@elodiecouderc.bsky.social is on ๐Ÿ”ฅ this month ! Our review (which the literature really missed, imho) giving an historical perspective on the methods used to study of mosquito-virus interactions in now online at @cp-trendsmicrobiol.bsky.social. Check it ou here: www.cell.com/trends/micro...

01.09.2025 13:26 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

RIP Margaret Rossiter, who coined the phrase the Matilda Effect (amongst many others), a phenomenon too many women will have seen first hand

30.08.2025 19:49 โ€” ๐Ÿ‘ 37    ๐Ÿ” 13    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

Thank you to our funders @pasteur.fr @ibeidlabex.bsky.social @sorbonne-universite.fr @agencerecherche.bsky.social @cnrsecologie.bsky.social for supporting our work!

28.08.2025 07:42 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ‘So proud to share @elodiecouderc.bsky.social work on the role of Vago-like genes in mosquito immunity. Please read her thread to get a sneak-peek of our work and find the full study here: rdcu.be/eCPmG

28.08.2025 07:42 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Yes! This is cytochrome P4503A4 - it is a very large family and their activity spans from detoxification, metabolism and many more cellular processes. In our case, the exact mechanism linking our P450 with dengue virus is unknown - might be metabolism (my first guess), or something else ...

19.08.2025 14:25 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thank you Alain!

19.08.2025 14:21 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thank you Olaya !

19.08.2025 14:21 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thank you ! So much more work to do indeed :)

19.08.2025 14:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

This was one of the most exciting, exploratory, long and difficult project I ever got to work on and I thank everyone who contributed, shared ideas and asked questions about it at meetings. Thanks to our funders @pasteur.fr @agencerecherche.bsky.social for their continuous support !

18.08.2025 12:05 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

It also raises new questions about the role of metabolism in DENV infection and the unexplored/mysterious link between DENV susceptibility and insecticide resistance. (2/3)

18.08.2025 12:05 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Our study is now published in @natcomms.nature.com and describes the 1st definitive identification of genetic variants linked to DENV susceptibility in Aedes aegypti mosquitoes. (1/3)

18.08.2025 12:05 โ€” ๐Ÿ‘ 30    ๐Ÿ” 10    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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David Hall & @vectorimmunity.bsky.social highlight @merklinglab.bsky.social & colleaguesโ€™ Cell Genomics article on #mosquito cellular responses in #midgut & #fatbody after #bloodfeeding. #Aedes #aegypti #scRNAseq #Metabolomics @iastateresearch.bsky.socialโ€ฌ โ€ฌ

authors.elsevier.com/a/1lbEr5Eb1x...

13.08.2025 11:48 โ€” ๐Ÿ‘ 17    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

go.bsky.app/36RdG8Z

14.07.2025 23:41 โ€” ๐Ÿ‘ 294    ๐Ÿ” 163    ๐Ÿ’ฌ 28    ๐Ÿ“Œ 5
4 research institute march together hand in hand for diversity and inclusion in science ยฉ Franck Aubry

4 research institute march together hand in hand for diversity and inclusion in science ยฉ Franck Aubry

ยฉ Franck Aubry

ยฉ Franck Aubry

ยฉ Franck Aubry

ยฉ Franck Aubry

๐ŸŒˆ United for diversity in science ๐ŸŒˆ
Researchers from Institut Pasteur joined the 2025 Pride March alongside @institutcurie.bsky.social, Les Cordeliers Research Center, @institutcochin.bsky.social @institutimagine.bsky.social

๐Ÿ‘ฉโ€๐Ÿ”ฌ Because diverse labs make better science.
#DiversityInScience

30.06.2025 12:36 โ€” ๐Ÿ‘ 50    ๐Ÿ” 20    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

๐ŸŽ‰ Our study is now published in Cell Genomics ! Thank to our reviewers for helping us further improve our work, and congratulations to @tompvial.bsky.social who lead this project and the entire team that made it possible ! www.cell.com/cell-genomic...

26.06.2025 10:20 โ€” ๐Ÿ‘ 38    ๐Ÿ” 15    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0

Awesome post-doc position available within the @maringerlab.bsky.social ! I can highly recommend applying to @pirbrightinst.bsky.social - Kevin and Trevor are wonderful PI's to be working with !

04.06.2025 12:23 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Changes to the 2026 and 2027 Work Programmes With the launch of the competitions for grants under ERC Work Programme 2026 in July of this year, several changes to the submission of applications and the evaluation of proposals will apply. The mai...

Planning to apply for #research #funding from the ERC?

From the next application rounds, expect changes to the:

โ€ข proposal structure
โ€ข evaluation process
โ€ข extra funding you can request
โ€ข eligibility for Starting & Consolidator #Grants (from 2027)

More ๐Ÿ‘‡ europa.eu/!RPHWvv

02.06.2025 10:02 โ€” ๐Ÿ‘ 145    ๐Ÿ” 102    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 17

Had the pleasure of listening to @ardemp.bskyverified.socialโ€™s lecture yesterday at @pasteur.fr - and seeing a live demonstration of the Piezo tattoo !

29.05.2025 07:45 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Wrapped up a 4 seminar Tour de ๐Ÿ‡ซ๐Ÿ‡ท with stops in Lyon, Strasbourg, and Paris (IBPS, Pasteur). Had a blast with fellow scientists across the pond, lots of convo about the current US landscape. You might recognize Jean-Marie Lehn, Jean-Pierre Changeux, and Christine Petit. Also: white asparagus season!

28.05.2025 21:11 โ€” ๐Ÿ‘ 46    ๐Ÿ” 1    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0
A graphic for the Marie Skล‚odowska-Curie Actions (MSCA), showing a historical portrait of Marie Skล‚odowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skล‚odowska-Curie Actions โ€“ โ‚ฌ404.3 million to support postdoctoral researchersโ€

A graphic for the Marie Skล‚odowska-Curie Actions (MSCA), showing a historical portrait of Marie Skล‚odowska-Curie overlaid with an image of four young researchers walking down a hallway. The European Commission logo is in the top left. Text reads: "Marie Skล‚odowska-Curie Actions โ€“ โ‚ฌ404.3 million to support postdoctoral researchersโ€

Choose Science. Choose Europe.

A new Marie Skล‚odowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.

With a budget of โ‚ฌ404.3 million, it will support around 1,650 researchers from Europe and beyond.

Apply by 10 September โ†’ europa.eu/!fBTMgF

08.05.2025 10:12 โ€” ๐Ÿ‘ 960    ๐Ÿ” 563    ๐Ÿ’ฌ 15    ๐Ÿ“Œ 99

Had a wonderful time at the #EMBLChromatin meeting in Heidelberg last week with @sumeyye-ozhan.bsky.social who was sponsored by a @pasteur.fr - @events.embl.org travel award ! @sebbaumgarten.bsky.social ;)

19.05.2025 18:48 โ€” ๐Ÿ‘ 13    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congratulations on getting the poster prize !! ๐Ÿฅณ
Also very nice meeting you at the conference :)

19.05.2025 18:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Maladie de Lyme : comment sโ€™en protรฉger ? - Sรฉbastien Bontemps Gallo - 10' de prรฉv'
YouTube video by Pasteur Lille Maladie de Lyme : comment sโ€™en protรฉger ? - Sรฉbastien Bontemps Gallo - 10' de prรฉv'

@sebbontempsgallo.bsky.social , Chercheur @cnrs-hautsdefrance.bsky.social @cnrsbiologie.bsky.social

Maladie de #Lyme : comment sโ€™en protรฉger ?

18.05.2025 10:31 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Our paper is now published in its final form: rdcu.be/elV6u @biomedcentral.bsky.social @salehlabparis.bsky.social @merklinglab.bsky.social @pasteur.fr

15.05.2025 06:57 โ€” ๐Ÿ‘ 16    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

That's amazing - congratulations to you all!

16.04.2025 14:30 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

This is super cool - very much looking forward to reading the pre-print and the book. Congratulations to all of you for an another amazing study, it makes me miss the Drosophila field even more ;)

01.04.2025 11:04 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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