🏳️‍🌈🪱🧬 rogerdjp

Our discovery of an epidermal membrane-associated periodic scaffold that protects axons from damage is out now in Science Advances and featured on the cover!

Congratulations to Sean, Igor and Dat for their wonderful and inspiring work! @coakleylab.bsky.social

www.science.org/doi/10.1126/...

09.01.2026 05:05 — 👍 8 🔁 3 💬 0 📌 0

An epidermal membrane-associated periodic skeleton restricts endocytosis to stabilize neuron-epidermal attachment and preserve axons An epidermal membrane periodic scaffold protects axons from damage.

Latest paper is now out and features on the cover of Science Advances 👉 tinyurl.com/vea5862x

Very grateful Igor Bonacossa Pereira, Dat Le & Massimo Hilliard @hilliardlab.bsky.social for their creativity & passion.

Read more about it 👉
tinyurl.com/56awjda5
& 👉 tinyurl.com/2vp8p8uk

08.01.2026 02:02 — 👍 14 🔁 8 💬 0 📌 2

Home The Asia-Pacific Worm Meeting (APWM) is the premier scientific conference for the Asia Pacific Caenorhabditis elegans research community, which is one of the fastest-growing worm research communities ...

Excited to announce the 11th Asia-Pacific Worm Meeting to be held in Darwin, Australia, 21-24 July 2026!! Registration and abstract submission are open now. More info at sites.google.com/monash.edu/a....

02.12.2025 04:51 — 👍 0 🔁 0 💬 0 📌 0

Caenorhabditis elegans, imaged with confocal laser scanning microscopy, and modeled by surface rendering software. Stock image.

All hail Caenorhabditis elegans, one of the most researched organisms on Earth. Collaborative data sharing in the nematode research community led to four Nobel Prize-winning discoveries about human development and disease. In PNAS: https://ow.ly/uNqU50Xyj4e

26.11.2025 19:01 — 👍 22 🔁 15 💬 0 📌 0

EMBL Australia Group Leader, Neural Regeneration - Monash University, Monash (AU) job with Monash University | 12844439 Shape the Future of Regenerative Medicine – Become an EMBL Australia Group Leader at Monash University, Australian Regenerative Medicine Institute

An exciting opportunity at the Australian Regenerative Medicine Institute in Melbourne!
www.nature.com/naturecareer...

14.09.2025 22:55 — 👍 0 🔁 0 💬 0 📌 0

Gas-sensing neurons prime mitochondrial fitness to offset metabolic stress Animals integrate environmental and internal cues to maintain homeostasis and health. The mitochondrial stress response is an essential cytoprotective mechanism, and priming its activation provides a survival advantage. Here, we show that the Caenorhabditis elegans receptor guanylyl cyclase GCY-9 regulates neuropeptide signalling from carbon dioxide sensing neurons to govern a non-canonical mitochondrial stress response in the intestine. This stress response induces atypical mitochondrial chaperone transcription, confers mitochondrial stress resistance, and increases mitochondrial membrane potential and respiration. GCY-9 loss disrupts pathogen avoidance, leading to indiscriminate feeding. We show that starvation decreases GCY-9 expression and propose that the resultant cytoprotective program is launched to offset risks associated with this behaviour. Thus, environmental sensing by peripheral neurons can pre-emptively enhance systemic mitochondrial function in response to metabolic uncertainty. One-Sentence Summary Protecting mitochondria by integrating environmental signals ### Competing Interest Statement The authors have declared no competing interest. National Health and Medical Research Council, GNT1137645, GNT2000766

Check out our pre-print on how gas sensing neurons enable animals to anticipate mitochondrial stress!

www.biorxiv.org/content/10.1...

07.07.2025 05:14 — 👍 5 🔁 2 💬 1 📌 0

What a wonderful International Worm Meeting. Thanks to Cathy Savage-Dunn @cswormlab.bsky.social
and Baris Tursun @baristursun.bsky.social for organising #worm25!!

Meeting old friends and new, a Nobel Prize celebration, and finding out that worms can hear! The talks and posters were exceptional.

05.07.2025 02:42 — 👍 10 🔁 0 💬 0 📌 0

“Do you have any advice for aspiring young scientists?”

“Do genetics.” *mic drop*

#worm25

30.06.2025 02:01 — 👍 91 🔁 22 💬 0 📌 1

Thanks Dave!

29.06.2025 21:19 — 👍 1 🔁 0 💬 0 📌 0

Functional depletion of MDT-29 during the larval germ line development in #Celagans boosted fecundity through an expansion of the germline stem cell pool and decreased germ cell apoptosis.🪱

Learn more about this #GENETICS study from the @rogerdjp.bsky.social lab: buff.ly/21pVeb6

23.05.2025 22:02 — 👍 1 🔁 1 💬 0 📌 0

Check out our new research published @genetics-gsa.bsky.social

09.05.2025 07:03 — 👍 4 🔁 0 💬 0 📌 0

Cell Biology of the Nervous System: Cellular Mechanisms of Communication The exploration of the cell biological aspects of nervous system development, function and health continues delivering groundbreaking pieces of information that push forward our understanding of brai…

I highly recommend attending this exciting EMBO workshop.

meetings.embo.org/event/25-cel...

28.02.2025 00:44 — 👍 4 🔁 1 💬 1 📌 1

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