Differential activation of cGAS in naked mole rats! An exciting addition to our understanding of species-specific mutations tailoring the cGAS-STING pathway in individual organisms
www.science.org/doi/10.1126/...
@mygalperin.bsky.social
Lead Scientist at the Division of Intramural Research (formerly NCBI), NLM, NIH. Bacterial signaling, c-di-GMP, c-di-AMP, protein domains, COG database
Differential activation of cGAS in naked mole rats! An exciting addition to our understanding of species-specific mutations tailoring the cGAS-STING pathway in individual organisms
www.science.org/doi/10.1126/...
All science arises only because of the shared broader community. I want to especially recognize Rotem Sorek @soreklab.bsky.social Aude Bernheim @audeber.bsky.social our collaborators and the many wonderful labs and scientists in the field bringing together human and bacterial antiviral research!
09.10.2025 16:44 โ ๐ 7 ๐ 1 ๐ฌ 0 ๐ 0Blavatnik National Awards
Blavatnik National Awards
Blavatnik National Awards
Blavatnik National Awards
Congratulations to Philip J. Kranzusch, Ph.D., Professor of Cancer Immunology and Virology, who was one of three scientists awarded top honors at the 2025 Blavatnik National Awards for Young Scientists.
Watch to learn more about his work: bit.ly/4pZUDkF
Viral AlphaFold Database (VAD) is live in Science Advances
~27,000 predicted viral protein monomers & homodimers
Conserved folds across bacteria, archaea & eukaryotic viruses
New toxinโantitoxin system KreTA uncovered
Vast โfunctional darknessโ remains uncharted
www.science.org/doi/10.1126/...
Excited to be part of this collaboration with the Burrows lab exploring twitching and surface surface sensing by P. aeruginosa. This work further delineates a role for the T4P motor proteins and pili for surface sensing.
journals.asm.org/doi/10.1128/...
@asm.org
Two fungal genera use two distinct pathways to synthesize psilocybin
onlinelibrary.wiley.com/doi/full/10....
Our story describing the Panoptes bacterial immune defense system is now finally peer-reviewed and published today! www.nature.com/articles/s41...
01.10.2025 16:05 โ ๐ 85 ๐ 43 ๐ฌ 4 ๐ 0Also in Spanish ;-)
larepublica.es/2025/09/27/d...
Thrilled to be a coauthor in this story ๐ Check out our latest publication on the archaellum - spoiler: it's an archaellum in bacteria ๐ฑ Who would have thought? Thank you to all the authors, and especially @sshamphavi.bsky.social for really keeping this paper rotating ๐
17.09.2025 17:56 โ ๐ 6 ๐ 2 ๐ฌ 0 ๐ 0Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...
Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
And a major contribution from @vikramalva.bsky.social
19.09.2025 12:44 โ ๐ 3 ๐ 0 ๐ฌ 0 ๐ 0And here is the published version of the work from @selimlab.bsky.social, @mygalperin.bsky.social, Dubnau labs and @thethormannden.bsky.social labs
(superb collaboration)
ComFB, a widespread family of c-di-NMP receptor proteins
www.pnas.org/doi/10.1073/...
Registration is open! Come join us at the sensory transduction in microorganisms GRC! Spread the word! www.grc.org/sensory-tran...
12.09.2025 06:04 โ ๐ 12 ๐ 11 ๐ฌ 0 ๐ 0Some thoughts on metabolism and metabolic pathway holes (PMID: 40892933)
pnas.org/doi/10.1073/....
Prioritising Microbiology in Secondary Education Addresses Emerging Scientific-Social-Educational Challenges and Competency Needs
#MicrobialBiotech by Lara Amorim, Conceiรงรฃo Santos, and Kenneth Timmis
enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...