The meeting abstracts for the 2026 AAAAI Annual Meeting are now online.

Here is the link to the index on our homepage, including late breaking abstracts:

www.jacionline.org/programs_abs...

The February issue of JACI is now online! Check it out here: jacionline.org/current
Read the Editors' Choice summaries from the February issue here (free to read/download): authors.elsevier.com/a/1mYyZ_25Pv...

The January issue of JACI is now online! Check it out here: jacionline.org/current
Read the Editors' Choice summaries from the January issue here (free to read/download): authors.elsevier.com/a/1mOPaKs2xL...

The December issue of JACI is now online! Check it out here: jacionline.org/current
Read the Editors' Choice summaries from the December issue here (free to read/download): authors.elsevier.com/a/1mD9bKs2xL...

The November issue of JACI is now online! Check it out here: jacionline.org/current
Read the Editors' Choice summaries from the November issue here (free to read/download): authors.elsevier.com/a/1m2z7Ks2xL...

Gen Z woman eats snack on plane—horror at announcement that comes next "I was planning on sleeping during the flight … and wanted to have a quick bite," the young woman told Newsweek.

Check out this Newsweek article that features research in JACI: www.newsweek.com/passenger-ea...

Free Access: Cutting-Edge Immune Dysregulation Articles: Journal of Allergy and Clinical Immunology Download started.

Did you know JACI features a list of our recent cutting-edge articles on Immune dysregulation? Check it out here - all Open Access!

The October issue of JACI is now live, featuring a theme on the thymus. View the issue here!
buff.ly/BEHXa0l

The latest issue of JACI has now posted - check out the Editors Choice here:

Greater focus on allergy prevention by NHS needed to protect children – MP Labour’s Becky Gittins is pressing the Government to adopt advice which recommends babies are weaned early if they show signs of an allergy.

Article from the UK focusing on advocacy for peanut allergy prevention drawn in part from current JACI article (pubmed.ncbi.nlm.nih.gov/36521802/) on early introduction of peanuts.

www.the-independent.com/news/uk/home...

The September issue of JACI is now online! Check it out here: jacionline.org/current
This month's theme focuses on Personalized Medicine. Special thanks to Mohamed Shamji, who helped coordinate this issue.
Read the Editors' Choice summaries here (free): authors.elsevier.com/a/1ljA5Ks2xL...

The August issue of JACI is now online! jacionline.org/current

This month's theme focuses on Complement. Special thanks to Kathleen Sullivan, who helped coordinate this issue.

Read the Editors' Choice summaries from the August issue here (free): authors.elsevier.com/a/1lYd6Ks2xL...

Allergies seem nearly impossible to avoid — unless you’re Amish One Amish community living in northern Indiana is considered one of the least allergic populations ever measured in the developed world.

While over 50% of U.S. children test positive for common allergens, only ~7% of Amish children do. Asthma rates run just 1–2% in Amish Children vs. ~8–10% in non-Amish kids. Their secret? See this Washington Post article that cites research from JACI. wapo.st/4odEBmq

The July issue of JACI is now online! Check it out here: jacionline.org/current
This month's theme focuses on Endotypes in Allergy/Immunology.

Read the Editors' Choice summaries from the June issue here (free to read/download): authors.elsevier.com/a/1lN0bKs2xL...

Biomarker-driven drug development for allergic diseases and asthma: An FDA public workshop The US Food and Drug Administration (FDA) hosted a workshop on February 22, 2024, to discuss the status of biomarkers in drug development for allergic…

Clinical trials of therapies for asthma and food allergy are complex, and there is intense interest in the development of biomarkers to predict natural disease history and response to therapy. Read a summary of a US FDA-hosted workshop discussion. bit.ly/4juKdVD

Update on the genetics of allergic diseases The field of genetic etiology of allergic diseases has advanced significantly in recent years. Shared risk loci reflect the contribution of genetic fa…

Our understanding of the genetic etiology of allergic diseases has grown significantly in recent years. Read about key advances in the field, with a focus on common genetic variants that increase disease risk. bit.ly/45CWrIr

A call to standardize exposure and outcome measures in birth cohort studies on asthma and allergic diseases

Climate change is affecting outdoor and indoor allergen exposures, and diagnostic and treatment strategies should limit exposure and facilitate desensitization. An American Academy of Allergy, Asthma & Immunology Work Group Report shares 4 steps. Read on. bit.ly/4kP95bB

A call to standardize exposure and outcome measures in birth cohort studies on asthma and allergic diseases

Birth cohort studies have provided invaluable insights into risk factors for allergic diseases and asthma in children. They also have their limitations. Should we standardize population descriptors, exposures, and outcomes measures from diverse cohorts? bit.ly/4mJBHoJ

The normal, the abnormal, and the at risk: How can old and new birth cohort studies help?

Traditionally, birth cohort studies are longitudinal, prospective observational studies of parents and their children. A Paradigms and perspectives piece discusses how birth cohort studies are evolving to incorporate methodologic innovations. Read on. bit.ly/3SyhzIn

Advancing birth cohort studies using administrative and other research-independent data repositories: Opportunities and challenges The birth cohort study design is an essential epidemiologic tool for investigating the developmental origins of health and disease. Birth cohorts have…

The use of administrative data, or data from research-independent repositories, offers a valuable tool for birth cohort studies. It also brings challenges. How have administrative data have enhanced asthma, allergy, and immune disorder birth cohorts? bit.ly/43M6fgK

Structural determinants of peanut-induced anaphylaxis Human IgE mAbs recognizing peanut allergens have recently become available, but we lack a detailed understanding of how these IgEs target allergens.We…

Studies of human IgE and its targeted epitopes on allergens have been limited. A study now shares a molecular map of the IgE antibody response to key peanut allergens. The issue also includes editorial commentary on the findings. bit.ly/3ZhS6Xc

The June issue of JACI is now online! Check it out here: jacionline.org/current
This month's theme focuses on Birth Cohorts. Special thanks to Tina Hartert and Andrea Apter, who helped coordinate this issue.
Read the Editors' Choice summaries here: authors.elsevier.com/a/1lCq7Ks2xL...

Efficacy and safety of GR1802 in uncontrolled chronic rhinosinusitis with nasal polyps: Placebo-controlled phase 2 trial Anti–IL-4 receptor subunit alpha (IL-4Rα) treatments can effectively treat eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). However, t…

Data from a phase 2 trial of GR1802, a novel anti-IL-4Ra monoclonal antibody, for the treatment of patients with uncontrolled chronic rhinosinusitis with nasal polyps suggest that the treatment is well-tolerated and effective. Here’s more. bit.ly/44F8VPn

Antibody-secreting cell repertoires hold high-affinity anti-rocuronium specificities that can induce anaphylaxis in vivo Neuromuscular blocking agents (NMBAs) are muscle relaxants used to assist mechanical ventilation but lead in 1 per 10,000 anesthesia cases to severe a…

Rocuronium is widely used to assist in mechanical ventilation. In a small number of anesthesia cases, it can lead to anaphylaxis. New data shed light on the underlying mechanisms and suggest novel diagnostic tools for rocuronium hypersensitivity. bit.ly/3SJJ15H

Direct epitope study using human IgE mAbs against peanut allergens

Human IgE mAbs that recognize peanut allergens are now available. How do these IgEs target allergens? Read about a structural map of the IgE antibody response to two key peanut allergen proteins. The issue includes editorial commentary on the findings. bit.ly/3Zftm1O

New data suggest that chronic rhinosinusitis with nasal polyps pathobiology may involve autoreactive humoral immunity, with some cases exhibiting molecular mimicry-driven autoimmune features triggered by microbial infections. Read the Editors’ Choice paper. bit.ly/3YP6Dtf

Short-chain fatty acids have been shown to be locally produced in areas of the body other than the gut in response to disease. What role might local short-chain fatty acid concentrations hold in obstructive airway diseases? Here’s a Brief report. bit.ly/430eTJy

Why do some upper respiratory illnesses provoke asthma exacerbations while the majority do not? An Editors’ Choice study identifies transcriptome-wide gene expression changes associated with common colds that progress to asthma exacerbation. Learn more. bit.ly/44EGKQL

Airway inflammation plays a key role in asthma, and the contributing molecular pathways, especially in type 2 inflammation characterized by eosinophilia and higher fractional exhaled nitric oxide, are not clear. Read new findings here. bit.ly/4jRGcM1

Rhinoconjunctivitis phenotypes are described based on aeroallergen sensitization and symptom severity and seasonality. Do these phenotypes fully reflect patterns of symptoms at a population level in children with asthma? Read Editors’ Choice findings. bit.ly/4keX9jc