IMPORTANT IMPORTANT IMPORTANT IMPORTANT
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
@sthyme.bsky.social
Associate Professor @ UMass Chan Medical School BMB Department; PhD @ UW Baker Lab; PD @ Schier Lab; Down Syndrome, ID, zebrafish, computation, protein engineering. MomX3!
IMPORTANT IMPORTANT IMPORTANT IMPORTANT
Please watch the workshop video and COMMENT by 5:00 Monday 7/14
This is the source of the "no more model organism only grants in NIH-funded research" decree.
Public comments have been opened back up!
Research with animals is critical for providing evidence-based knowledge in the pursuit of human health. Broadly reducing research projects with animals threatens public health and will greatly stall the development of new therapeutics for diseases!
"There have been many funding cuts to cancer research, and it's playing out many ways. Here are a few stories from people I know. I spend time in cancer circles. I am an recliner advocate nowadays. 
Brooke is 24 years old, has a baby and a toddler, and has stage 4 B-cell lymphoma..."
UAB Neurobiology is hiring up to 4 new tenure-track faculty as part of 3 new open-rank searches. Come join our vibrant, supportive, and growing neuroscience community!
uab.peopleadmin.com/postings/23916
uab.peopleadmin.com/postings/23944
uab.peopleadmin.com/postings/24010
We get news of an apparent breakthrough in pancreatic cancer β usually a death sentence, one of the cancers with the worst outcomes β and Trump and Musk are blowing up NIH and with it future cancer cures. 
The American people didnβt vote for this.
Not even close to 49.8% did.
THIS IS HUGE! A cancer vaccine developed by Yale University and DFCI shows MAJOR promise. Results of an early-phase trial reveal ALL patients with ADVANCED stage kidney cancer had successful anti-cancer immune responses AND have remained CANCER-FREE approximately THREE years after treatment. π§ͺπ§΅β¬οΈ
26.02.2025 17:00 β π 11345 π 3400 π¬ 220 π 241One of the remarkable things about #NIH is how rigorously its grants, research, and employees are reviewed. NIH science and scientists are held to a high standard by external reviewers β via study sections and councils, or BSC/site visit reviewers. And the reviews have teeth. π§ͺ
25.02.2025 12:26 β π 406 π 74 π¬ 8 π 8Guardian story about Federal Register issue is up.
www.theguardian.com/us-news/2025...
New York Times article now up on Federal Register stuff.
www.nytimes.com/2025/02/21/s...
1/n
COALITION OF MAYORS ACROSS U.S. FILE AMICUS BRIEF IN OPPOSITION TO TRUMP ADMINISTRATIONβS DRASTIC CUTS TO FEDERAL RESEARCH FUNDING Led by the City of Boston, MA, City of Cleveland, OH, the Metropolitan Government of Nashville and Davidson County, TN, the Mayor of Gainesville, FL, and the Mayor of Salt Lake City, UT, over 40 mayors, cities, and counties argue that NIH cuts will cause job losses, economic disruption, and undermine U.S. competitiveness BOSTON - Thursday, February 20, 2025 - Late yesterday, Mayor Michelle Wu co-led a coalition of Mayors from across the United States in writing and filing an amicus brief in federal district court in Boston to stop the Trump Administration's drastic and illegal cuts to federal research funding and immediate job losses in cities nationwide. Over 40 mayors, cities, and counties from across the country joined the brief. These cities are home to universities and hospitals that employ hundreds of thousands of Americans in cutting edge medical and scientific research, and the federally-funded research in these communities has made the United States the global leader in scientific discovery. The brief seeks a temporary restraining order against the Trump Administration, alongside the research universities, medical schools, hospitals, and 22 states that are plaintiffs in the three cases filed last week in federal district court. βFor decades, Congress has made a clear choice to use federally-funded research to invest in cities, build a broadly-distributed infrastructure for scientific discovery, create jobs, and drive economic growth in communities across the United States,β said Mayor Michelle Wu. βWe join with cities across the country β in red states, purple states, and blue states β to stop this illegal action that will cause layoffs, lab closures, and undermine scientific progress in American cities. I thank Massachusetts Attorney General Andrea Campbell for her leadership on behalf of the research institutions of Boston.β
This amicus brief is in response to the abrupt February 7, 2025 announcement by the National Institutes of Health (NIH) of an immediate reduction in funding for scientific and medical research institutions across the country. Under the NIHβs new policy, which temporarily went into effect on Monday, February 10, payments for indirect costs reimbursed to research universities would be capped at 15%, down from 30-70%. The brief makes clear that NIH funding cuts would devastate research institutions in cities across the county, cause job losses, create severe economic disruption, and undermine a critical pillar of strength and civic pride in cities across the United States. The cuts would also undermine critical medical and scientific research that residents are counting on, including cancer, diabetes, and heart disease, and jeopardize the citiesβ and countryβs position of global leadership on scientific advancement. βThe Gainesville community depends on this highly efficient, dependable investment of our tax dollars back into our cityβs innovation economy,β said Harvey L. Ward, Mayor, City of Gainesville, Florida. βIβm glad to join other mayors in highlighting the vital role NIH funding plays in the lives of everyday hardworking American families.β βThe breadth and diversity of this coalition highlights the devastating and widespread impact of these NIH funding changes, from Alzheimerβs research to cancer clinical trials,β said Jill Habig, Founder and CEO of Public Rights Project. βWeβre proud to partner with mayors, cities, and counties in opposing this threat to critical federal funding and the health and vitality of our communities.β On Monday, February 10th, twenty two states and associations of medical schools, hospitals, and universities, filed three related cases, and secured a temporary restraining order preventing the Trump Administration from slashing the reimbursement rates. That initial order will be revisited this week in a hearing scheduled for Feb. 21.
The Public Rights Project served as amici counsel. The full list of mayors, cities and counties who joined the brief is below. Local Governments and Mayors City of Boston, Massachusetts City of Cleveland, Ohio Harvey L. Ward, Mayor, City of Gainesville, Florida Metropolitan Government of Nashville and Davidson County, Tennessee Erin Mendenhall, Mayor, City of Salt Lake City, Utah City of Alameda, California City of Albuquerque, New Mexico Allegheny County, Pennsylvania City of Baltimore, Maryland Emma Mulvaney-Stanak, Mayor, City of Burlington, Vermont Township of Canton, Michigan Town of Chapel Hill, North Carolina City of Chicago, Illinois Sandra Welch, Mayor, City of Coconut Creek, Florida City of Columbus, Ohio City of Easthampton, Massachusetts Daniel Biss, Mayor, City of Evanston, Illinois City of Fairfax, Virginia Harris County, Texas Ravinder S. Bhalla, Mayor, City of Hoboken, New Jersey Quinton Lucas, Mayor, Kansas City, Missouri Indya Kincannon, Mayor, City of Knoxville, Tennessee City of Madison, Wisconsin Jeff Silvestrini, Mayor, City of Millcreek, Utah Anissa Welch, Mayor, City of Milton, Wisconsin Montgomery County, Maryland City of New Haven, Connecticut Dontae Payne, Mayor, City of Olympia, Washington Adrian O. Mapp, Mayor, City of Plainfield, New Jersey Sue Noack, Mayor, City of Pleasant Hill, California City of Pittsburgh and Ed Gainey, Mayor, City of Pittsburgh, Pennsylvania City of Providence, Rhode Island John Clark, Mayor, Town of Ridgway, Colorado City of Rochester, New York City of Sacramento, California City and County of San Francisco, California City of Santa Monica, California Constantine H. Kutteh, Mayor, City of Statesville, North Carolina Lisa Brown, Mayor, City of Spokane, Washington Tishaura O. Jones, Mayor, City of St. Louis, Missouri City of St. Paul, Minnesota Dennis R. McBride, Mayor, City of Wauwatosa, Wisconsin
The City of Boston is leading 40+ mayors, cities, and counties in an amicus brief against the Trump Administration's drastic and illegal cuts to federal research fundingβcuts that will lead to immediate job losses nationwide.
20.02.2025 22:16 β π 1482 π 428 π¬ 34 π 80Reaching out to all Americans through the media to explain how decreasing funding of the NIH will have irreversible harm for developing therapies for all diseases. Please spread the word to your families and friends and contact your congressional representatives.
www.nbcnews.com/science/scie...
This is incredibly stressful to our Alzheimer's community (families and researchers). There are Alzheimer Disease Research Centers that are in limbo now - no council meetings means no notice of awards, means all the research we are doing to slow or prevent this disease is paused indefinitely.
18.02.2025 00:55 β π 92 π 37 π¬ 0 π 4The court ordered that NIH grant funding be unfrozen, so The Regime found a way around it. For NIH grants to be funded, a review panel must rank them. In order for a review panel to meet, they must post it on the Federal Register. Submissions to the Federal Register are now on hold βindefinitelyβ.
20.02.2025 02:32 β π 838 π 508 π¬ 30 π 37Important article. This center was taking new approaches to studying Alzheimerβs and other dementias. 
Everyone who knows someone with dementia is being hurt by Trumpβs cuts to medical research. π§ͺ
Scientists studying neuroscience, diabetes, autism and bird flu became emotional as they spoke to the Guardian about the possibility of losing their lifeβs work.
19.02.2025 15:01 β π 122 π 56 π¬ 7 π 7The MMR vaccine is 97% effective at preventing measles infection.
But infants under 12 months old are not eligible for the vaccine, leaving them vulnerable.
When measles spreads due to low vaccination rates, it puts our youngestβand most defenselessβchildren at the greatest risk.
If anyone has been in touch with press covering the NIH situation broadly (firings, funding freeze etc), please encourage them to cover the sinister way in which HHS is preventing grant review and funding from happening, by blocking posting to the Federal Register.
17.02.2025 17:24 β π 184 π 113 π¬ 8 π 9We are hearing that Andy Singleton, director of a new and promising Alzheimer's research center at NIH, just announced his resignation.
This will disrupt innovative new Alzheimer's work to go beyond the "amyloid hypothesis." Bad news for anyone who's been touched by this disease. π§ͺ
A screenshot of an email notifying Spotsylvania parents that funding for a program for youth with disabilities has been canceled
the richest man in the world has decided that your kids don't deserve special education programs
16.02.2025 18:14 β π 10694 π 4694 π¬ 351 π 628I'm #standingupforscience because when I was diagnosed with stage 3 melanoma in 2018, I was terrified. The survival statistics for my type of melanoma was around 20%. But these statistics did not include the lives saved from the recent NCI and CRI funded studies of immunotherapy drugs. 1/6
16.02.2025 15:03 β π 143 π 30 π¬ 5 π 0Talk to your neighbors. Talk to your family. Talk to your friends. Tell everyone what is happening and why science matters (this is not a USA-only post, because we know this is happening everywhere)
16.02.2025 19:19 β π 90 π 34 π¬ 2 π 0Please help NIH: speak to the press, speak to your local TV, tell everyone you know:
Trump and Musk are killing cancer research. 
Theyβre chasing science out of the US, making the US poorer. 
Thank you for what youβre doing. /end
Hey neuroscientists: were you, your lab or any of your ongoing projects caught up in any of the latest NIH firings? You can find me on Signal at avaskham.54 if you want to chat. π§ͺ
#neuroskyence
The value NIH research provides far exceeds that of trying to get a rocket to Mars. The NIH staff cuts are unconscionable.
16.02.2025 03:47 β π 105 π 17 π¬ 2 π 0The damage today (actually yesterday) to the intramural program appears to especially bad.
It also appears (although I need more confirmation) that most or all of the tenure track investigators in their first 2 years in several, and perhaps all, institutes were terminated.
7/n
Thanks to all of the NIHers and their friends who reached out to me. I am still here (DM me or Signal jeremymberg.78)
I still have a very incomplete picture but based on what I have been told, the damage to NIH and to many wonderful people who work(ed) there is/was impossible for me to imagine
1/n
Got word that several NIH employees in a group working on cancer clinical trials got terminated via email this evening.
βThe [cancer research] trials will literally not be able to function without us.β 
Trump and Musk are killing cancer research. π§ͺ
Excerpt from a public letter Roald Dahl wrote encouraging people to vaccinate their children. Olivia, my eldest daughter, caught measles when she was seven years old. As the illness took its usual course I can remember reading to her often in bed and not feeling particularly alarmed about it. Then one morning, when she was well on the road to recovery, I was sitting on her bed showing her how to fashion little animals out of coloured pipe-cleaners, and when it came to her turn to make one herself, I noticed that her fingers and her mind were not working together and she couldnβt do anything. βAre you feeling all right?β I asked her. βI feel all sleepy,β she said. In an hour, she was unconscious. In twelve hours she was dead. The measles had turned into a terrible thing called measles encephalitis and there was nothing the doctors could do to save her. That was twenty-four years ago in 1962, but even now, if a child with measles happens to develop the same deadly reaction from measles as Olivia did, there would still be nothing the doctors could do to help her. On the other hand, there is today something that parents can do to make sure that this sort of tragedy does not happen to a child of theirs. They can insist that their child is immunized against measles. I was unable to do that for Olivia in 1962 because in those days a reliable measles vaccine had not been discovered. Today a good and safe vaccine is available to every family and all you have to do is to ask your doctor to administer it.
The measles outbreak in Texas is reminding me of the public letter Roald Dahl wrote about losing his daughter to measles in 1962, just before the vaccine was publicly available.
15.02.2025 17:48 β π 26830 π 11806 π¬ 408 π 548