Lisa

GREGoR: accelerating genomics for rare diseases - Nature The GREGoR consortium provides foundational resources and substrates for the future of rare disease genomics.

Read about our efforts in the NHGRI's GREGoR Consortium to tackle some of the hardest-to-solve rare disease diagnoses. Online now www.nature.com/articles/s41...

Over my 6 weeks of furlough I did a lot of birding, some baking (but less than you’d think), monitored my local TJ Maxx for ‘the good lip balms’, got in all of the doctors appointments I’d been putting off, and painted my bathroom (just finished that this morning). Glad to go back to work though.

apparently I am going back to work tomorrow for the first time in SIX WEEKS. I worked so hard to learn everyone’s name at the weather office that is hosting me, and now I’m going to be starting all over 🫠

DOGE holdover who pushed for deep cuts at HHS is headed to the Navy Rachel Riley, a former McKinsey partner, helped execute sweeping layoffs at the health department this spring. Behind the scenes, her methods sparked turmoil.

"In September, Riley pushed for the near-dissolution of the NIH’s CSR, a roughly 500-person division that reviews grant applications at the health research agency, POLITICO learned. [...]almost all the positions in the division were slated for elimination."
www.politico.com/news/2025/10...

Yours has like, SHADING. It reminds me of the Trogdor episode of Strong Bad. “I employed some chiaroscuro shading” then I light it on fire because I am a talentless brute

I wish I had your skill. I was barely able to manage centered and legible lettering

I actually had heard the the potential NIEHS appointment 2 days ago and broke the news about it at the STAT Summit. I did not share any details since I did not have confirmation.

Eric Green shared his views about the importance of process and applicant quality.

1/5

I’m currently going with: laying around like a slug

I had basically given up hope of finding something local. I’d been to pretty much every federal office in town asking if they could take me.

I haven’t been able to make plans beyond a month out for pretty much all of 2026, because I’ve had a management directed reassignment to our headquarters hanging over my head the entire time. At least now I can feel a little more settled.

Also yes this is crazy. I’m lucky that it looks pretty likely that I’ll be able to get on a wifi network in this office, but most of our staff hosted by other agencies have to spend 40 hours a week on their phone hotspot, doing Teams meetings etc.

After 16+ years working remotely for the NIH, today is my last day in my home office. To meet the new requirement of reporting to a federal office 5 days a week, I’m going to be working out of the local office of the National Weather Service (super grateful to all the fed agencies hosting our staff)

Ok come on I do

Corners first then outer. Inner only once you’ve eaten all the best parts.

Oh my god she’s wrong. I stand with you. Jeez Alisa.

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.

Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

And likely Program Staff.

If you want a real glimpse into what is happening inside the National Institutes of Health under Trump 2.0, check out our latest from Important Context/ @accountabilityji.bsky.social

A dozen people working at the agency spoke out candidly on the condition of anonymity.

Scientists protest White House plan to put political appointees in charge of grant-making Trump administration proposal is seen as a way to make NIH institute and center directors political appointees.

New STAT story about Schedule F situation

www.statnews.com/2025/05/23/n...

1/n

NIH killed grants on orders from Elon Musk’s DOGE Court documents and internal correspondence show the cost-cutting force has broad control over the world’s largest public biomedical funder.

Who's calling the shots at NIH?

Sworn testimonies and internal e-mails reveal for the first time the breadth of DOGE's control over the world's largest public biomedical funder.

DOGE has provided lists of hundreds of grants to cut, and DOGE is now reviewing ALL NIH awards before they're released

Institutionalizing politicized science The opening months of the Trump administration represent a historic disruption to America’s scientific agencies. Staff have been fired or reassigned in the name of efficiency, resulting in chaos. Gran...

More info on proposed Schedule F: www.science.org/doi/10.1126/...

🚨 A new rule would let career scientists like NSF/NIH program officers be replaced by political appointees

Already 14,000+ public comments, deadline is Friday

📣 Comments can be short. Courts consider them—and scientists with NSF/NIH experience are especially impactful

Speak up! shorturl.at/WKuBj

RFK Jr. said multiple times during his house and senate hearings today that no scientists have been fired from federal agencies. Our reporting has shown that hundreds, if not thousands, of scientists have been let go from NIH/CDC/FDA

On a Nature news article reporting that NIH planned to suspend subawards for foreign collaborations: “No, that’s false. There’s going to be a policy on tracking subawards. The NIH and the government should be able to see where the money’s going.” “I’m really uncomfortable with this conversation, because you’re like, actually spreading rumors that you don’t know anything about. … Nature also is spreading rumors. Halt foreign collaborations, that’s not true.” “We’re working on the policy, Jocelyn. You shouldn’t be reporting rumors. I know there’s leaks all over here, but the leaks don’t actually reflect what’s happening. Don’t write about rumors. It actually makes the things that you and I care about worse. Like it spreads panic.” Later that day, NIH released a policy that halted future subawards to foreign scientists and said they will need to apply directly for money under a system still in development.

With NIH director Jayanta Bhattacharya dismissing my reporting as "false" and "spreading rumors" hours before releasing a policy that confirmed said "rumors," I feel compelled to respond.

Here's an inside look into how this story was reported. It was a weird one. 🧵

www.nature.com/articles/d41...

Budgets as Propaganda Trump's budget proposal formalizes the paranoid style as government policy

New, from me: I am dorky enough to actually read (ok, skim) budgets, and have never seen anything like Trump’s, which has converted a formal and professional document into a propagandistic screed to justify draconian cuts.

Lets take a look. 🧵
donmoynihan.substack.com/p/budgets-as...

this antivax stuff is genuinely bewildering. like what do you mean you don’t know if vaccines are safe? why exactly do you think child mortality rates have plummeted since the beginning of the 20th century? why is it that you are not worried about getting polio or smallpox anymore?

SORRY. Sorry.
Have we seen this *incredible* news video coming out of Queensland? Wait for the witness/witnesses statement

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too many notes. Just cut a few and it’ll be perfect

Like I am not a pushover in any other area of my life but for some reason LensCrafters has my number