Shahid Siddique

Gene editing of the E3 ligase PIRE1 fine-tunes reactive oxygen species production for enhanced bacterial disease resistance in tomato An E3 ligase helps control plant immune responses and regulates reactive oxygen species production, offering a strategy to boost disease resistance in leav

Excited this MS is out! Here, we genome edited Pire in tomato, a conserved E3 ligase controlling NADPH oxidase accumulation in Arabidopsis. Edited lines exhibited enhanced resistance to foliar bacterial pathogens, but not two root colonizing pathogens. #PlantImmunity
academic.oup.com/plcell/artic...

03.06.2025 00:52 — 👍 32    🔁 13    💬 0    📌 1

New paper alert! A chromosome-scale genome of Meloidogyne hapla. A devastating plant pathogen. But this is not just another genome.
www.biorxiv.org/content/10.1...
🧵
NO CANONICAL TELOMERES but a novel 16-mer repeat at chromosome ends. A new mechanism for chromosome-end maintenance?

23.05.2025 16:25 — 👍 10    🔁 6    💬 3    📌 0

A Chromosome-scale Reference Genome of Meloidogyne hapla reveals localized recombination hotspots enriched with Effector Proteins https://www.biorxiv.org/content/10.1101/2025.05.21.654606v1

23.05.2025 12:04 — 👍 3    🔁 4    💬 0    📌 0

Worms just keeping everything good a weird with holocentric chromosomes AND weird caps at the ends. Awesome to see such an example of the diversity of solutions to segregating and maintaining information in chromosomes!

23.05.2025 16:42 — 👍 2    🔁 1    💬 0    📌 0

-Effectors are often domain-less, and enriched in high-recombination regions → hinting at adaptive evolution
Note: I am wrongly labelled as first author. Its
@pallavishakya.bsky.social
's work. A new version with correct author arrangement has been submitted.

23.05.2025 16:27 — 👍 2    🔁 0    💬 0    📌 0

-Genome structure validated with F2 linkage mapping. A first in plant-parasitic nematodes
-Structural variation between isolates: fissions, fusions, rearrangements
-Sharp zones of high recombination on most chromosome arms

23.05.2025 16:26 — 👍 0    🔁 0    💬 0    📌 0

New paper alert! A chromosome-scale genome of Meloidogyne hapla. A devastating plant pathogen. But this is not just another genome.
www.biorxiv.org/content/10.1...
🧵
NO CANONICAL TELOMERES but a novel 16-mer repeat at chromosome ends. A new mechanism for chromosome-end maintenance?

23.05.2025 16:25 — 👍 10    🔁 6    💬 3    📌 0

Alison Blundell Named Recipient of Outstanding Student Award from Society of Nematologists UC Davis doctoral candidate Alison Blundell, shown here at the 2023 SON conference, is the recipient of the 2025 John M.

Congrats. Well deserved Alison

nematology.ucdavis.edu/news/alison-...

03.05.2025 22:53 — 👍 8    🔁 1    💬 1    📌 0

Beautiful work. Congrats @yichangsung.bsky.social all coauthors @gittacoaker.bsky.social

24.04.2025 15:13 — 👍 2    🔁 0    💬 2    📌 0

Diet-regulated transcriptional plasticity of plant parasites in plant–mutualist environments | PNAS Crop pathogens often lack exclusive access to their host and must interact with plants concurrently engaged with numerous other symbionts. Here, we...

Important work on nematode diet regularion.
www.pnas.org/doi/10.1073/...

17.04.2025 21:51 — 👍 7    🔁 3    💬 0    📌 0

Very excited to see my first first-authored paper published in @pnas.org . We found the first regulator of effector production in plant-parasitic nematodes! Congratulations to co first author @clempellegrin.bsky.social and all other authors. www.pnas.org/doi/10.1073/...

11.03.2025 10:05 — 👍 42    🔁 18    💬 0    📌 1

🪱🔬 Nematode Nerds Unite! 🔬🪱
Huge thanks to the Groen lab for hosting us at UCR Nematology! From exciting research discussions to sharing our love for these tiny but mighty guys with many NEMA-enthusiastics from this department, it was a truly NEMA-zing experience!
🧬🔬
#WormScience #UCD #UCR

01.03.2025 06:42 — 👍 3    🔁 1    💬 0    📌 0

New to bluesky - would appreciate a "retweet" please, so I can find everyone from twitter.

26.02.2025 11:36 — 👍 27    🔁 48    💬 7    📌 0

UC (Davis+Riverside) Nematology Meet up! @chjlin.bsky.social @damarisgodinez.bsky.social @simoncgroen.bsky.social

27.02.2025 14:53 — 👍 9    🔁 0    💬 1    📌 0

Activation of a helper NLR by plant and bacterial TIR immune signaling Plant intracellular nucleotide-binding leucine-rich repeat (NLR) receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain sense pathogen effectors to initiate immune signaling. TIR domain...

doi.org/10.1126/scie...

26.11.2024 16:16 — 👍 4    🔁 2    💬 0    📌 0

Great news. Many congrats Deepak.

21.11.2024 03:46 — 👍 1    🔁 0    💬 0    📌 0