This was only possible thanks to an amazing team:🙏 Franz Mittermaier, HenrikePlanert, Sabine Grosser, Imre Vida, Jörg Geiger and the critical contribution of our clinical collaborators @neurocure.bsky.social
13.12.2025 07:59 — 👍 3 🔁 0 💬 0 📌 0This was only possible thanks to an amazing team:🙏 Franz Mittermaier, HenrikePlanert, Sabine Grosser, Imre Vida, Jörg Geiger and the critical contribution of our clinical collaborators @neurocure.bsky.social
13.12.2025 07:59 — 👍 3 🔁 0 💬 0 📌 0
Despite tissue coming from 23 patients, the same four subtypes and their characteristic synaptic interactions were conserved within and across individuals. This suggests that increased diversity and subtype-specific interactions are general principles of human cortical organization.
13.12.2025 07:59 — 👍 5 🔁 0 💬 1 📌 0
Using multi-neuron patch-clamp, we observed a great heterogeneity of electrophysiological properties across neurons and identified 4 subtypes: SlowAP, FastAP, DoubSpk & LowRin. These subtypes exhibited distinct morphological features and specific connectivity rules.
13.12.2025 07:59 — 👍 4 🔁 0 💬 1 📌 0
🥳Excited to share our latest human multipatch paper, now out in @natneuro.nature.com
🧠 We studied the cellular and synaptic physiology of human L2–3 pyramidal neurons and identified subtype-specific local connectivity rules across individuals.
www.nature.com/articles/s41...
Join us: penglab.de
Amazing study by @fxmittermaier.bsky.social on analog signalling in human axons!
31.12.2024 16:32 — 👍 1 🔁 0 💬 0 📌 0
Axonal and synaptic mechanisms in the HUMAN neocortex that could underlie memory consolidation during slow-wave #sleep . Check out our latest research published today in Nature Communications ( @natureportfolio.bsky.social ). 🎉
Link: www.nature.com/articles/s41...
Very cool multi-patch study from the Jake Watson on human hippocampus connectivity!! Congrats!
11.12.2024 20:48 — 👍 2 🔁 1 💬 1 📌 0