Luke Allsopp

Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏

www.imperial.ac.uk/media/imperi...

Systematic discovery of antibacterial and antifungal bacterial toxins - Nature Microbiology Genome sequence mining and computational analyses lead to the discovery and functional characterization of conserved bacterial toxins with activity against bacteria and fungi.

Several years of work with several great collaborators, that combined computational biology, molecular microbiology, biochemistry, structural biology and mycology assay culminated in today's publication on discovery of novel bacterial toxins:
www.nature.com/articles/s41...

Preparing for ETOX meeting in Bilbao with Yaara, Tracy, and Luke @lukeallsopp.bsky.social @proftracypalmer.bsky.social

This week I celebrate 10 years at FILM, the Facility for Imaging by Light Microscopy @imperialcollegeldn.bsky.social @imperialnhli.bsky.social
Thank you to all the students, researchers and colleagues who used the facility and supported us!
Here's to many more years of imaging 🥳🎉🔬

Now that’s commitment!

Today is Wear Yellow Day to raise awareness of and fundraise for Cystic Fibrosis. Teams of @janedaviescf.bsky.social, @lukeallsopp.bsky.social and Hughes in yellow. Researching towards unlocking a life unlimited for people with CF ‪@cysticfibrosis.org.uk
www.cysticfibrosis.org.uk/get-involved...

Harriet Ellis, a postdoc in @lukeallsopp.bsky.social's Group, is uncovering how Pseudomonas aeruginosa – a key bacterial threat in cystic fibrosis – adapts & causes infection. 💛🦠 #CFweek

Discover how her work could help fight lung infections 👇 blogs.imperial.ac.uk/nhli/2025/06...

#Myth busting #immunology, promoting #critical thinking and the awe of #science !!!
Super enjoyed @dandavis101.bsky.social lecture at the @ri-science.bsky.social on Saturday!

Enjoyed @dandavis101.bsky.social lecture at @ri-science.bsky.social on Saturday night. Myth busting and promoting critical thinking with a clear passion for scientific discovery!!

Two distinct host-specialized fungal species cause white-nose disease in bats - Nature The identification of two cryptic species of the fungal pathogen that causes white-nose disease in bats highlights the need to integrate studies of genetic variability in pathogens into disease survei...

White-nose disease in bats:

The causative agent is not a single fungal species but 2 sympatric cryptic species with host specialization & geographically differentiated populations

The source of the North American species has been traced to giant maze-caves of a region in Ukraine

#MicroSky

“I was confident that macrophages would digest the microplastics and everything would be fine. I was truly surprised by what we found,” explained Adam Soloff, PhD, to Futura on his latest study on microplastics, which he presented at #ATS2025.

Read more: www.futura-sciences.com/en/i-was-rea...

A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics An upstream open-reading frame in Escherichia coli regulates expression of the downstream genes in response to diverse translation stresses.

A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics
elifesciences.org/articles/101...

Teachers Are Not OK AI, ChatGPT, and LLMs "have absolutely blown up what I try to accomplish with my teaching."

I talked to 15 teachers/professors about how AI and ChatGPT is ruining their lives:

www.404media.co/teachers-are...

Pioneering spatial map of the airways could transform understanding of asthma | Imperial News | Imperial College London Researchers have identified distinct differences in the spatial organisation of cells in the airway of healthy people and those with asthma.

Our researchers have created the first high-res map of the lung airway wall, revealing how cell organisation & interactions are disrupted in asthma 🫁

Published in @natimmunol.nature.com, it's a key step towards understanding the mechanisms that drive the disease

www.imperial.ac.uk/news/264294/...

**NEW Doctoral Training Programme just launched!!** This exciting programme on Microbial Genomics for Health Protection is joint between @imibirmingham.bsky.social and UKHSA @ukhsa.bsky.social. 9 brilliant projects available!!

Brilliant Athena Swan Lecture by Dame Kate Bingham at @imperialcollegeldn.bsky.social ‘getting up in the morning and knowing your work will have an impact on someone- is my biggest driver’

Ministers confirm UK Research and Innovation budget will fall - Research Professional News Funding agency’s allocation drops by £300m for 2025-26, despite rising R&D spending at science department

UKRI's budget for 2025-26 confirmed...finally

5 months after spending review, and 1 day before financial year starts

As @resprofnews.bsky.social has been reporting, it's less than flat cash (£8.8bn), despite DSIT's R&D budget rising

Via @annamckie.bsky.social

More details to come

A western dietary pattern during pregnancy is associated with neurodevelopmental disorders in childhood and adolescence Nature Metabolism - Leveraging four large, longitudinal, prospectively-followed mother–child cohorts, this study shows that a western diet in early–mid-pregnancy is associated with...

Impactful study in @naturemedicine.bsky.social Eating more plants during pregnancy linked to lower neurodevelopmental disorders - #WOW
www.nature.com/articles/s42...

Watching the US take a wrecking ball to science 💔 🤯

Reminder of the importance of doing science in the open. Put data, software, resources in public domain, where no single govt can erase them. This is our collective knowledge. Distributed data systems are essential.

www.nature.com/articles/s41...

🏆 Research integrity consultant and image forensics expert @elisabethbik.bsky.social has uncovered fraudulent data in over 7,600 scientific papers and exposed the practices of ‘paper mills’ that produce counterfeit scientific articles. She is honoured with the €200K Individual Award. Congrats!

Group Leader (Microbes and Food Safety) - Quadram Institute Group Leader (Microbes and Food Safety) Full or Part Time We are looking for an exceptional scientist with a research focus on bacterial foodborne pathogens or microbial spoilage. You will join other ...

Principal Investigator / Group Leader post @quadraminstitute.bsky.social within the Microbes and Food Safety strategic programme - all research related to food safety and food spoilage. Unsure whether your research interests fit, contact us informally quadram.ac.uk/vacancies/gr...

Decoding viruses and defying limits: Professor Wendy Barclay appointed Regius Professor A life dedicated to understanding viruses with pandemic potential

From decoding deadly viruses to leading in #GlobalHealth crises—Prof Wendy Barclay’s impact is undeniable.

Now, she’s the first woman appointed Regius Professor of Infectious Disease at @imperialcollegeldn.bsky.social.

Learn more this Women at Imperial Week 👉 www.imperial.ac.uk/Stories/Wend...

If you are supervising an international student who is trying to write in their non-native language - tell them how awesome they are. They often feel incompetent, frustrated and even stupid. In reality they're really smart - just doing something very complicated. Tell them.

Using AI-driven computer vision and high-throughput multiplexed human cell infection assays to dissect intra- and intercellular signalling networks and discover new antimicrobials at Queen’s Universit... PhD Project - Using AI-driven computer vision and high-throughput multiplexed human cell infection assays to dissect intra- and intercellular signalling networks and discover new antimicrobials at Que...

Funded 4-year #PhD in the exciting BBSRC NILAB program. @wwiem-qub.bsky.social

Receive multidisciplinary training, develop #infection models and #AI image analysis to reveal bacterial & viral disease mechanisms & discover new antimicrobials. Fight #AMR

Get in touch!
Details: tinyurl.com/e5k6ptua

Congratulations to Luca Robinson for passing his viva today! Massive achievement #PhD @imperialnhli.bsky.social

Nice spotlight on @janedaviescf.bsky.social

Great to have Carmen visiting the lab from the Albesa lab! Some fun times and great science!

🚨Ready to be part of a pioneering microbiology lab that pushes the boundaries of scientific discovery? We have an **open postdoctoral position** in our lab, where we delve into the fascinating world of T6SS, effectors, mobile genetic elements, and everything in between! @erc.europa.eu -funded 🦠

Trump 2.0: an assault on science anywhere is an assault on science everywhere Nature - US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.

“US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.”

Strong and welcome stance from @Nature

www.nature.com/artic...
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Establishment and characterization of persistent Pseudomonas aeruginosa infections in air–liquid interface cultures of human airway epithelial cells | Infection and Immunity The ubiquitous gram-negative bacterium Pseudomonas aeruginosa is categorized as an ESKAPE pathogen (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudom...

Establishment and characterization of persistent Pseudomonas aeruginosa infections in air-liquid interface cultures of human airway epithelial cells

in Infect Immun from Susanne Häussler

journals.asm.org/doi/10.1128/...