Abraham Alahmad, PhD 🔬🧠💊🇫🇷🇺🇸🇸🇾's Avatar

Abraham Alahmad, PhD 🔬🧠💊🇫🇷🇺🇸🇸🇾

@scientistabe.bsky.social

Associate Professor of Pharmacology. Expertise on the blood-brain barrier (BBB) and response to hypoxic injury, and glucose metabolism. Also teach pharmacokinetics to PharmD student. Sci-Fi lover, metalhead, retrocomputing. He/Him.

641 Followers  |  199 Following  |  42 Posts  |  Joined: 01.07.2023  |  2.3921

Latest posts by scientistabe.bsky.social on Bluesky

Fungus is raising awareness of something true and serious, which you don’t seem to completely understand, it’s important to take her seriously.

04.05.2025 21:05 — 👍 1    🔁 0    💬 1    📌 0

I second that, and agree with you on that point.

04.05.2025 20:07 — 👍 1    🔁 0    💬 1    📌 0
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Safari microbien — Episode 2 : un peu d’histoire de culture Safari microbien — Episode 2 : un peu d’histoire de culture   L'épisode 1, c'est par  là . Pour cultiver des bactéries, on a longtemps con...

Salut à toi!

Si jamais tu manques de sujets pour briller pendant le dessert voilà un article ⬇️ sur l'invention de la culture en boîte de Petri à la faveur de recettes de cuisine. Une histoire de tranche de patate oubliée et de confitures.

duxpacis-biologica.blogspot.com/2025/04/v-be...

20.04.2025 11:21 — 👍 47    🔁 18    💬 4    📌 3

Idk who needs to hear this but there is literally zero evidence to support a lab leak as the origin of SARS-CoV-2 and there is a lot of evidence opposing a lab leak origin

19.04.2025 19:52 — 👍 1065    🔁 216    💬 44    📌 9

Pas de ce que je me souviens, par contre on a la variante qui touche les cervides (cerfs, biches) comme le "Chronic Waste Disease" qui peut etre problematiques pour les amateurs de la viande de gibier (quoique on a pas de preuve de transmission a l'humain).

21.02.2025 16:40 — 👍 1    🔁 0    💬 3    📌 0
Behind the scenes, the company was also quietly dismantling a system to prevent the spread of misinformation. When the company announced on Jan. 7 that it would end its fact-checking partnerships, the company also instructed teams responsible for ranking content in the company’s apps to stop penalizing misinformation, according to sources and an internal document obtained by Platformer.

The result is that the sort of viral hoaxes that ran roughshod over the platform during the 2016 US presidential election — “Pope Francis endorses Trump,” Pizzagate, and all the rest — are now just as eligible for free amplification on Facebook, Instagram, and Threads as true stories.

Behind the scenes, the company was also quietly dismantling a system to prevent the spread of misinformation. When the company announced on Jan. 7 that it would end its fact-checking partnerships, the company also instructed teams responsible for ranking content in the company’s apps to stop penalizing misinformation, according to sources and an internal document obtained by Platformer. The result is that the sort of viral hoaxes that ran roughshod over the platform during the 2016 US presidential election — “Pope Francis endorses Trump,” Pizzagate, and all the rest — are now just as eligible for free amplification on Facebook, Instagram, and Threads as true stories.

NEW: Meta has quietly dismantled the system that prevented misinformation from spreading in the United States. Machine-learning classifiers that once identified viral hoaxes and limited their reach have now been switched off, Platformer has learned www.platformer.news/meta-ends-mi...

15.01.2025 00:51 — 👍 26391    🔁 9435    💬 1397    📌 993

And it’s such a bizarre non sequitur. Like, even on the racist premise that aiming for a more diverse Fire Dept automatically entails lowering standards, are we supposed to understand that WILDFIRES are out of control because… individual firefighters aren’t skilled enough? How?

09.01.2025 02:21 — 👍 897    🔁 137    💬 43    📌 7
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New year, new me. #backtothelab #science #stemcells

02.01.2025 16:01 — 👍 3    🔁 0    💬 0    📌 0
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How extreme was the weather this year? Is a question we, @wwattribution.bsky.social , get asked every year. Looking back at the events we studied in detail & some new stats, we try to give an answer www.worldweatherattribution.org/when-risks-b... - in short: it was pretty bad, but things can change!

27.12.2024 12:41 — 👍 286    🔁 156    💬 5    📌 7
30/08/2019 tweet de Mariani: À #Sednaya, bonne surprise dans le restaurant qui nous propose un #CotesDuRhone !! 
Malgré l’embargo et les sanctions  qui frappent la #Syrie, bravo à nos viticulteurs qui ont réussi à distribuer leur vin jusqu’ici 👏👏👏

30/08/2019 tweet de Mariani: À #Sednaya, bonne surprise dans le restaurant qui nous propose un #CotesDuRhone !! Malgré l’embargo et les sanctions qui frappent la #Syrie, bravo à nos viticulteurs qui ont réussi à distribuer leur vin jusqu’ici 👏👏👏

Image de synthèse salle de torture de Saydnaya selon les rares survivants

Image de synthèse salle de torture de Saydnaya selon les rares survivants

Image satelite de la prison de Saydnaya, c'est la SEULE image qu'on a de cette prison

Image satelite de la prison de Saydnaya, c'est la SEULE image qu'on a de cette prison

Image de synthèse d'objets de torture de Saydnaya selon les rares survivants

Image de synthèse d'objets de torture de Saydnaya selon les rares survivants

Lorsque la prison de #Saydnaya sera libérée, ceux qui vont ouvrir les portes craignent de découvrir toute l'horreur de ce lieu de torture et d'assassinat d'opposants.
Ceci n'avait pas empêché #ThierryMariani et #NicolasBay de déguster un Côtes-du-Rhône à Saydnaya en 2019

07.12.2024 15:12 — 👍 232    🔁 95    💬 9    📌 5
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Robert F Kennedy Jr and his favorite conspiracy theories The post critiques Robert F. Kennedy Jr.'s unfounded conspiracy theories, including AIDS denialism, claims linking antidepressants to mass shootings, theories about pesticides affecting child sexuality, and assertions that WiFi causes cancer. Each claim is debunked by scientific evidence, emphasizing the dangers of misinformation in health discussions.

Robert F Kennedy Jr and his favorite conspiracy theories

The post critiques Robert F. Kennedy Jr.'s unfounded conspiracy theories, including AIDS denialism, claims linking antidepressants to mass shootings, theories about pesticides affecting child sexuality, and assertions that WiFi causes…

05.12.2024 22:24 — 👍 5    🔁 1    💬 0    📌 0
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'Bodies are piling up': Reporter finds GOP-led states are hiding abortion ban death toll Some Republican-led states that passed near-total abortion bans have mysteriously stopped collecting statistics on maternal mortality over the last couple of years — and some observers suspect it's no...

I warned that the GOP would cover up the negative impacts of their policies. www.rawstory.com/abortion-ban...

05.12.2024 18:07 — 👍 10572    🔁 4221    💬 372    📌 226

These clicks not gonna click themselves :p

04.12.2024 13:00 — 👍 1    🔁 0    💬 1    📌 0

Amazing watching journalists fawn over RFK Jr cuz he wants to reduce seed oil consumption (!) while totes ignoring that he’s an AIDS denialist, chemtrails truther, extreme anti-vaxx activist, & ivermectin peddler who thinks chemicals in water make kids trans & antidepressants cause school shootings!

04.12.2024 03:40 — 👍 424    🔁 80    💬 10    📌 1

RFK Jr. went to Samoa to tell people not to get their kids vaccinated. Dozens of babies died.

fuck you

04.12.2024 01:24 — 👍 967    🔁 221    💬 14    📌 2
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You are welcome! Again this is my personal opinion and would like to hear from seasoned colleagues more akin on brain drug delivery. But thing is certain: the headline is too sensational and clickbait. Oh well, PhDComics had it summarized well this issue :)

04.12.2024 12:44 — 👍 1    🔁 0    💬 1    📌 0

I would say, this delivery vector looks promising if you are pushing for antisense oligonucleotides delivery into the brain, but I have hard time seeing it being translated for other small molecules (liposomes being so far the best we can do) or larger molecules (bispecific TfR antibodies kind work)

04.12.2024 12:26 — 👍 1    🔁 0    💬 1    📌 0
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Une question qu'on me pose souvent quand je dis que je suis astrophysicien, et dont la réponse est relativement facile: "Pourquoi le ciel est bleu?". Je pense que c'est approprié pour commencer sur Bluesky!
Thread👇

03.12.2024 09:55 — 👍 1114    🔁 191    💬 38    📌 16
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Nurse Burnout and Patient Safety, Satisfaction, and Quality of Care This systematic review and meta-analysis evaluates the magnitude and moderators of the association between nurse burnout and patient safety, patient satisfaction, and quality of care.

Le burnout chez les soignant.e.s est associé à une moins bonne prise en charge en termes de qualité, de sécurité et de satisfaction

Le biais est que les organisations de soin déficientes sont à la fois pourvoyeuses de burn-out et de mauvaises prises en charge

jamanetwork.com/journals/jam...

02.12.2024 20:02 — 👍 21    🔁 12    💬 2    📌 1

ça rapporte la désinformation!
Note "rigolote": Xavier Azalbert, que je connais très bien, est pourtant suffisamment argenté pour financer lui-même (ou faire financer par ses multiples autres business) un blog tel que celui qu'est devenu France-Soir. Mais autant faire payer la collectivité non?

03.12.2024 11:13 — 👍 150    🔁 31    💬 2    📌 3
Tweet de Raphael Grably :
« Sans commenter mon propre procès, je me permets de partager une information intéressante (et inédite à ma connaissance), partagée par l'avocate de M. Azalbert pendant l'audience: France-Soir a levé 2,5 millions d'euros de dons depuis 2020. Défiscalisables à 66% durant 4 ans. »

Citation du tweet de Maitre Eolas :
« Le hasard des audiences fait que je me trouve au procès opposant 
@xazalbert à @GrablyR  pour diffamation publique du second à l’encontre du premier. N’ayant pas de pédophile à défendre cet après midi, je vous propose un petit LT. »

Tweet de Raphael Grably : « Sans commenter mon propre procès, je me permets de partager une information intéressante (et inédite à ma connaissance), partagée par l'avocate de M. Azalbert pendant l'audience: France-Soir a levé 2,5 millions d'euros de dons depuis 2020. Défiscalisables à 66% durant 4 ans. » Citation du tweet de Maitre Eolas : « Le hasard des audiences fait que je me trouve au procès opposant @xazalbert à @GrablyR pour diffamation publique du second à l’encontre du premier. N’ayant pas de pédophile à défendre cet après midi, je vous propose un petit LT. »

🧮 Rapide calcul : En 4 ans, #FranceSoir a donc coûté 1.65 millions d'€ à la collectivité.

C'est sans doute ce qu'ils appellent "la presse libre et non subventionnée" 🙃

03.12.2024 11:06 — 👍 340    🔁 101    💬 10    📌 7
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My biggest concern? How did the authors ensured samples were taken and maintained under sterile conditions? Nowhere it is written and this is for me some serious concerns. You want samples extracted and frozen in a clean room, otherwise we end up with the same issue than meteorite.

02.12.2024 19:46 — 👍 2    🔁 0    💬 1    📌 0
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The remarkable complexity of the brain microbiome in health and disease Microbes in human brain and their potential contribution to neurodegenerative conditions such as Alzheimer’s disease (AD) have long been debated. We recently developed a new method (the electronic tre...

You are welcome. The pathobiome in AD makes sense, but the whole brain microbiome? As now it is a pre-print only, and seeing The Guardian buzzing off a pre-print is for me like someone trying to sell you a bear hide before actually having taken care of it. www.biorxiv.org/content/10.1...

02.12.2024 19:42 — 👍 1    🔁 0    💬 0    📌 0

Reviving this discussion. Yes, they used fresh human tissue. It is better than nothing (helluva to do brain PK in humans), the penetration rate (as %injected dose/g brain tissue) is rather impressive (~3% versus ~0.1% with antibodies like lenacemab/donanemab) but still we are delivering small cargo.

02.12.2024 18:43 — 👍 1    🔁 0    💬 1    📌 0
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Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease Microbial infections of the brain can lead to dementia, and for many decades microbial infections have been implicated in Alzheimer's disease (AD) pathology. However, a causal role for infection in A....

As a primer, link to the paper: alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

02.12.2024 17:47 — 👍 2    🔁 0    💬 1    📌 0

I have to say, shaking grounds by the title when it comes to the consensus and as now (before entering and reading the actual study) I am left with this two options: fact or fiction?

02.12.2024 17:46 — 👍 1    🔁 0    💬 0    📌 0

“Dammit Matou! What’s wrong with you!?!”

01.12.2024 20:41 — 👍 2    🔁 0    💬 1    📌 0
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Looks like there could be a split between the Republican Guard and Maher al-Assad’s Iranian-aligned 4th Division. This is incredible if true.

30.11.2024 18:41 — 👍 67    🔁 23    💬 2    📌 2
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California teacher dies of rabies after animal bites her in classroom The teacher died a month after encountering a bat in her Merced County classroom.

Rabies virus is the most lethal virus. Neuroinvasive rabies is a death sentence.

I cannot stress this enough: if you have any physical contact with a bat—especially a bite—get treatment immediately. If it gets into your central nervous system, you will die horribly.
www.sfgate.com/bayarea/arti...

30.11.2024 16:45 — 👍 977    🔁 403    💬 31    📌 66

Early reports that Russian and Syrian forces have fled Hama airbase.

More consequences of Putin’s war in Ukraine - he’s overcommitting troops to try to make progress in Ukraine and leaving himself vulnerable elsewhere.

Losing in two theaters at once is pretty impressive.

30.11.2024 17:17 — 👍 8230    🔁 1373    💬 185    📌 48

@scientistabe is following 19 prominent accounts