Lucina Uddin

The good news is that grants are getting reviewed at NIH. The bad news is that mine are not getting discussed. Sigh.

𝗪𝗵𝗮𝘁 𝗮𝗿𝗲 𝗯𝗿𝗮𝗶𝗻 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀?
Do they even exist...?
Join @lucinauddin.bsky.social who will present, followed by discussion in the Neuroscience & Philosophy Salon.
Open to all.
Date: Dec 9, 12pm EST-US
Register: umd.zoom.us/meeting/regi... (you need a zoom account which is free)
#neuroskyence

Looking for a post-bac RA position focused on the brain bases of affective and psychotic illness?
@holmeslab-bhi.bsky.social is hiring!
@cahbir.bsky.social @rutgersbhi.bsky.social @rutgersu.bsky.social @sobp-org.bsky.social @hitop-system.bsky.social @ohbmofficial.bsky.social

Consciousness science: where are we, where are we going, and what if we get there? Join me, @axc.bsky.social, @liadmudrik.bsky.social, @lucinauddin.bsky.social & @metzinger.bsky.social for a Frontiers Deep Dive at 3pm GMT. Registration link is below

Elusive Cures

Friends in all places! Join @lucinauddin.bsky.social and I for a conversation about the next steps for brain and mind research.

Where? Online.
When? December 16 5-6p PT
Who? Sponsored by the UCLA Semel Institute.
How? Free to register; link here.

www.friendsofsemelinstitute.org/events-reser...

In Buzzy Papers we set out to compile some of the most exciting neuroscience papers published in the past two years! A panel of 10 neuroscientists selected the papers from a preliminary list our editorial team assembled by considering publications in top neuroscience journals

🎉

Putting 50 years of neuroscience on the map Navigate the rise and fall of research topics over five decades using our interactive map, which is based on a semantic analysis of nearly 350,000 abstracts.

Navigate the rise and fall of research topics over five decades using The Transmitter's interactive map, which is based on a semantic analysis of nearly 350,000 abstracts in leading neuroscience journals. Explore more: www.thetransmitter.org/publishing/p...

#neuroskyence #StateOfNeuroscience

fMRI Course Instructors

❤️ Bluesky fMRI people! 3-day #fMRI course live online Jan 7-9, 2026.

#SPM, #ICA, GLM, connectivity, mediation, MRI physics, #DataScience with @vcalhoun.bsky.social and Kent Kiehl.

We love talking methods & connecting with colleagues! Come join us!

Register here:
sites.google.com/dartmouth.ed...

There has to be a better way!

After all these years, I’m still utterly flummoxed by the procedure for adding an enrollment report to an RPRR in eRA commons.

Thanks for sharing this incredible dataset, you guys are the best!

Understanding consciousness is one of the greatest scientific challenges of the 21st century, made urgent by rapid advances in AI. Join this #FrontiersForum webinar to explore our Frontiers in Science article on a new phase of consciousness science ➡️ fro.ntiers.in/x64CgqQpPXb

YouTube video by Organization for Human Brain Mapping OHBM 2025 | Keynote | Lucina Uddin | Towards a universal taxonomy of functional brain networks

ICYMI @ohbmofficial.bsky.social 2025 keynotes are now online! Here's mine: "Towards a universal taxonomy of functional brain networks" 🧠 www.youtube.com/watch?v=ZW9J...

Flyer with our pictures, a brain, and event details: 2-3:30p Saturday November 15th, Buena Vist Branch Library

Friends (and friends-of-friends) in LA: Please help spread the word!

On Saturday, November 15th 2p, @mameister4.bsky.social and I will be in conversation at the Burbank Library discussing bottlenecks and next steps for brain research.

It's free! Register here:
burbank.libnet.info/event/14639190

Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis Early psychosis (EP) is characterized by neurobiological changes, including alterations in resting-state functional connectivity (RSFC). We now understand that symptoms and neural changes may overlap ...

New from @haleyrwang.bsky.social: Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis - Biological Psychiatry www.biologicalpsychiatryjournal.com/article/S000...

Great catching up!

Thanks for a fun Halloween visit! Nothing scarier than the current funding situation 🧠👻🎃💀

That’s what I always say about you!

Advancing consciousness science Defining new directions in consciousness research and exploring implications for medicine, technology, and ethics

1/🧵 Out today in @frontiersin.bsky.social : “Consciousness science: where are we, where are we going, and what if we get there?” By @axc.bsky.social @liadmudrik.bsky.social, & me (a CIFAR & @erc.europa.eu production 🧠). www.frontiersin.org/journals/sci...

Amazing work on interoception and connectomics going on in @micahgallen.com ‘s group. Thanks so much for sharing with us today, excited to see what’s coming up next! 🧠

It’s not the thought that counts: Allostasis at the core of brain function The authors review evidence that the primary function of the brain, supported by distributed neural systems, is the predictive regulation of physiology (i.e., allostasis). An example from Alzheimer’s ...

It’s not the thought that counts: Allostasis at the core of brain function
www.cell.com/neuron/fullt...
#neuroscience

Looking forward to this upcoming Maryland visit on Halloween 🎃 bsos.umd.edu/event/dr-wil...

Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression Abstract. Ketamine produces fast-acting antidepressant effects in treatment resistant depression (TRD). Prior studies have shown altered functional dynamics between brain networks in major depression. We thus sought to determine whether functional brain network dynamics are modulated by ketamine therapy in TRD. Participants with TRD (n=58, mean age=40.7 years, female=48.3%) completed resting-state fMRI scans and clinical assessments (mood and rumination) at baseline and 24 h after receiving four ketamine infusions (0.5mg/kg) over two weeks. Healthy controls (HC) (n=56, mean age=32.8 years, female=57.1%) received the same assessments at baseline and after two weeks in a subsample without treatment. A co-activation pattern (CAP) analysis identified recurring patterns of brain activity across all subjects using k-means clustering. Statistical analyses compared CAP metrics including the fraction of time (FT) spent in a brain state, and the transition probability (TP) from one state to another over time and associations with clinical improvement. Follow-up analyses compared HC and TRD at baseline. Six brain state clusters were identified, including patterns resembling the salience (SN), central executive (CEN), visual (VN), default mode (DMN), and somatomotor (SMN) networks. Following ketamine, TRD patients showed decreased FT for the VN (p=7.4E-04) and increased FT for the CEN state (p=1.9E-03). For TP metrics, SN-CEN increased (p=5.8E-04) and SN-VN decreased (p=3.6E-03). Decreased FT for the SN associated with improved rumination (p=1.9E-03). At baseline, lower FT for CEN (p=5.70E-04) and TP for SN-CEN (p=0.016) and higher TP for SN-VN (p=2.60E-03) distinguished TRD from HCs. CAP metrics remained stable over time in a subsample of HCs (n=18). These findings suggest ketamine modulates brain network dynamics between SN, CEN and VN in TRD, which may normalize dynamic patterns seen in TRD at baseline towards patterns seen in controls. Changes in SN state dynamics may correspond to improvements in ruminative symptoms following ketamine therapy.

New from Brandon Taraku 🧠: Modulation of functional network co-activation pattern dynamics following ketamine treatment in major depression url: direct.mit.edu/imag/article...

We're a month further into the job market - how are things looking? The good news is that the market does seem to have been delayed: ~150 new listings have appeared since my last post. The bad news is that the total is still substantially lower than what it was during the covid dip.

@theabcdstudy.bsky.social

Want to learn more about the Adolescent Brain Cognitive Development study?👀 Check out the ABCD-ReproNim course! The Fall 2025 course is going on NOW✨ Students may have the opportunity to participate in the 2026 hackathon in Miami🏝️ For more info: abcd-repronim.org 🎉

Thanks for the figure @bttyeo.bsky.social 🙂🧠🙏🏽!

NIH awarded 37 percent fewer neuroscience-related grants in 2025 than in past years But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.

www.thetransmitter.org/funding/nih-...

Figure from paper showing "The Brain is ..." at the top and answers in a 2D embedding space at the bottom.

Complete this sentence, "The brain is ...".
What's your favorite answer? I'm team cluster 17/18.

Taken from this delightful paper by Taylor Bolt and @lucinauddin.bsky.social; results of text in >4 million peer-reviewed articles + text analytic tools.

pubmed.ncbi.nlm.nih.gov/39798046/