Gregor Russell

BIG Research Moments of 2025 - DEMENTIA RESEARCHER Join Alzheimer's Research UK for an online session reflecting on this years dementia news and the part the public play in moving clinical research forward.

Join Alzheimer's Research UK @alzheimersresearchuk.org for an online session reflecting on this years dementia news and the part the public play in moving clinical research forward. 16th December - 1pm

www.dementiaresearcher.nihr.ac.uk/event/big-re...

Oh dear. I had high hopes for Evoke. I was involved with the ELAD trial of liraglutide, which was negative overall but with some tantalising suggestions there could be some benefit on the secondary outcomes. This result is a bit of a blow.

😧

Another post from yesterday’s walk at Scarhouse reservoir in Nidderdale in #NorthYorkshire. Rained the whole way round so plenty of water still to make its way into the reservoir. Very reassuring after it was only 1/3 full at the end of summer!

#yorkshire

Scarhouse reservoir full at last!

#photography
#photooftheday
#stunday
#Yorkshire
#autumn2025

#Winterwalking in Scotland- Lochan na h-Earba
#Scotland
#photography
#landscapephotography
#photooftheday
#landscape

Abstract submissions for #AAIC26 are open! Share your landmark findings and shape the future of Alzheimer's disease and dementia research by presenting at the Alzheimer's Association International Conference 2026. Submit by Jan. 12, 2026: alz.org/AAIC

We’re at the ARUK Networking Meeting in Cardiff!
🧠 AI-driven neuroimaging talk by @lewishotchkiss.bsky.social
📊 Posters on Polygenic Risk Scores by Alieyeh Sarabandi & Aynthetic Data by Kafayat Adeoye
Come say hi and learn how DPUK drives dementia research!
#DementiaResearch #AIinHealthcare #DPUK

#Winterwalking in Scotland- stand of Scots pines in front of Creag Meagaidh
#Scotland
#photography
#landscapephotography
#photooftheday
#landscape

#Winterwalking in Scotland- Gulvain south top on a sunny November day. Bigger day than expected- only 987m but lots of ups and downs along the way, 1300m ascent in total, finished in the dark

#Scotland
#photography
#landscapephotography
#photooftheday
#landscape
#mountainmonday

Meet Isabella👋 A PhD student at our Doctoral Training Centre for Integrated Care in dementia at Leeds Beckett University. Her PhD focuses on how marginalised communities experience memory assessment and support for mild cognitive impairment (MCI). #DementiaResearch

Find out more shorturl.at/tQ6l4

Congratulations to Dishaa Sinha, one of the many outstanding women working with @dementiasplatform.bsky.social for her award at #WINAwards2025. She has done great work on our #FAST study and #GreatMinds register. #dementiaresearch #cognition #bloodbiomarkers #ageing #aging 👏👩‍🔬

Welcome the 6 early career researchers beginning their PhD projects in the Alzheimer’s Society Doctoral Training Centre for Integrated Care in dementia!

This Centre focuses on ways to provide better care and services for people living with dementia!

Find out more: sl1nk.com/JCEfC

Indeed, and I was being a bit melodramatic. Plenty of other possible causes.

Still, only 15 in the study, and one SAE (participant outcome - death)- I’d be monitoring the safety profile in any phase 2 study *very* carefully…

It was very atmospheric in the Pinewoods in #Harrogate the other day- autumn colours muted by the mist…
#photography
#photooftheday
#nature
#naturephotography
#Yorkshire
#autumn2025
#stunday

“One participant died months after the infusion” 😬

Alzheimer's Research & Therapy

Alzheimer's Research & Therapy launched a new Collection “Advances in Lewy Body Dementia Research”, edited by Kristian Steen Frederiksen and Paul C. Donaghy, that focuses on biomarker discovery, imaging techniques, and treatment strategies in Lewy body dementia.
bit.ly/4qZGaWu

#MedSky

Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission The 2024 update of the Lancet Commission on dementia provides new hopeful evidence about dementia prevention, intervention, and care. As people live longer, the number of people who live with dementia...

We did. High LDL cholesterol is the biggest modifiable risk factor for dementia.

Don’t take my word for it:

#Lancetcommisiondementia

www.thelancet.com/journals/lan...

Thanks Trisha!

Pinewoods, Harrogate, again- nature’s fireworks…
#photography
#photooftheday
#nature
#naturephotography
#Yorkshire
#autumn2025

Pinewoods, Harrogate- autumn in full flow…
#photography
#photooftheday
#nature
#naturephotography
#Yorkshire
#autumn2025

Living in a deprived neighbourhood increases your #dementia risk and now @psychiatry-ucam.bsky.social researchers know why.

@audreylow.bsky.social and Prof John O'Brien found links to brain vessel damage and poorer management of lifestyle factors known to affect dementia risk: bit.ly/3JNMxv7

🧪

National Institute on Aging infographic about depression and older adults

Four Things To Know About Depression and Older Adults nia.nih.gov/health/infog...

#depression #mentalhealth #Alzheimers #dementia #geriatrics #GeriSky

Pinewoods, Harrogate
#photography
#photooftheday
#stunday
#Yorkshire
#autumn2025

Good grief.

#dontlookup

- and that stopping Reform is the only game in town.

And it cuts both ways- if the Green rise and Labour slide were to continue, and the Greens were in the box seat to beat Reform/Tories in a constituency, then Labour should put the country first and not target that constituency

So if I was in the Green Party (and I have voted for them), I’d be working on the premise that it’s going to take a repeat of the last election- when there was massive tactical voting to keep out the Right- to stop Reform; and that, just on electoral arithmetic Labour have to be part of that…

“A week is a long time in politics”…

I can’t see how Labour recover to election-winning levels of support from where they are, but stabilising at about 20% seems entirely plausible, with the patchy distribution of support still giving them a decent number of seats

Can’t argue with any of that.

But what I would be wary of is assuming the polls now tell us much about what to expect at an election 2 or 3 years from now. Thatcher was dead and buried in the summer of 1981, but ended up with 3 terms. Johnson was a shoo-in for 3 terms and didn’t even see out 1

…plan for this scenario is.

I’ve asked you, and your answer is just “my assessment is right: what you say just won’t happen”

That serial denial there is a valid point to address, and restatement of the original proposition, is exactly what Labour and the Tories do.

#allthesame