Karthala system's Avatar

Karthala system

@karthala-system.bsky.social

Acousto-optic two-photon microscopy system karthalasystem.com

165 Followers  |  629 Following  |  2 Posts  |  Joined: 16.01.2025
Posts Following

Posts by Karthala system (@karthala-system.bsky.social)

Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience

If you are a PhD student or post-doc who wants to learn everything about #electrophysiology or #imaging, consider registering to the Paris Spring school in optical imaging and electrophysiology, that will take place in the center of Paris 11-23 May 2026. Application deadline Feb 2nd
parisneuro.ovh

28.01.2026 21:54 β€” πŸ‘ 15    πŸ” 15    πŸ’¬ 3    πŸ“Œ 0
Preview
Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...

iGluSnFR4 is now available @natmethods.nature.com

www.nature.com/articles/s41...

Glutamate indicators with increased sensitivity and tailored deactivation rates πŸ§ͺ

23.12.2025 13:21 β€” πŸ‘ 39    πŸ” 17    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

We are excited to announce that @karthala-system.bsky.social has been acquired by Imagine Optic.

More details available in the press release below :

09.12.2025 12:43 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

🧡 New paper out🚨🧠! Information about motion is key to vision. Head motion signals from the vestibular system robustly modulate visual cortex activity. Despite this profound modulation, we still don’t know how these signals reach visual cortex - or even what aspects of head motion are transmitted.

18.10.2025 07:00 β€” πŸ‘ 25    πŸ” 8    πŸ’¬ 1    πŸ“Œ 0
Preview
A sensitive orange fluorescent calcium ion indicator for imaging neural activity Genetically encoded calcium indicators (GECIs) are vital tools for fluorescence-based visualization of neuronal activity with high spatial and temporal resolution. However, current highest-performance...

#OCaMP is now on bioRxiv and reagents are available on #Addgene! πŸ§ͺ

A sensitive orange fluorescent calcium ion indicator for imaging neural activity

www.biorxiv.org/content/10.1...

31.07.2025 19:34 β€” πŸ‘ 39    πŸ” 21    πŸ’¬ 2    πŸ“Œ 2
Post image Post image

Mind the deadlines for our 11th international conference "BrainBody - Exploring bidirectional crosstalk between the central nervous system and the body"!
⏳ Early bird registration and abstract submission deadline: July 1st!
πŸ“… 1-3 October 2025
πŸ“ Bordeaux, France

πŸ‘‰ brainconf.u-bordeaux.fr/en/

16.06.2025 09:58 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Video thumbnail

Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social πŸš€
github.com/danionella/w...

12.05.2025 05:25 β€” πŸ‘ 195    πŸ” 54    πŸ’¬ 7    πŸ“Œ 3

(Plz repost)

I’ve been receiving some good news lately and will be hiring at all levels to expand the lab. Please get in contact if you are interested in reinforcement learning, neural plasticity, neural circuit dynamics, and/or hearing rehabilitation.

pierre.apostolides @ umich .edu

Tyvm

17.04.2025 09:53 β€” πŸ‘ 26    πŸ” 18    πŸ’¬ 1    πŸ“Œ 2
Video thumbnail

✨ Announcing a new glutamate indicator - iGluSnFR4! ✨

Launched as a pair, iGLuSnFR4s and iGluSnFR4f have high-sensitivity and fast activation/deactivation for recording synapses.

More on the indicators and what they are already revealing: www.biorxiv.org/content/10.1...

πŸ§ πŸ“ˆ

25.03.2025 22:24 β€” πŸ‘ 117    πŸ” 26    πŸ’¬ 3    πŸ“Œ 5
Preview
Standardized measurements for monitoring and comparing multiphoton microscope systems Nature Protocols - A set of procedures is described here for standardizing the evaluation of multiphoton microscope performance, covering laser power, pulse width optimizations, field of view,...

That was a fun project! Thanks to Rob Lees, Adam Packer, and all the co-authors for inviting me to participate.
rdcu.be/edQXi

17.03.2025 12:08 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Three images with figure excerpts from the paper, highlighting 1) single-spike detection analysis, 2) autocalibration analysis, and 3) non-linearity of calcium-to-fluorescence transfer functions and their effect on the reporting of complex spiking events.

Three images with figure excerpts from the paper, highlighting 1) single-spike detection analysis, 2) autocalibration analysis, and 3) non-linearity of calcium-to-fluorescence transfer functions and their effect on the reporting of complex spiking events.

Are you using GCaMP8 or are planning to switch from GCaMP6? Then check out this new preprint from our lab! www.biorxiv.org/content/10.1...

- Calcium imaging
- GCaMP8 vs. GCaMP6
- Spike inference
- Imaging + ephys ground truth

With F. Helmchen, K. Svoboda, M. Rozsa & X. Fang.

11.03.2025 11:30 β€” πŸ‘ 76    πŸ” 24    πŸ’¬ 2    πŸ“Œ 1
Post image

#SaveTheDateπŸ“’ Rdv for the 7th International Frontiers in Neurophotonics 2025 #FINS2025!

On the programme: experts in #microscopy and #neuroscienceπŸ”¬πŸ§ 

πŸ—“οΈFrom 6 to 9 October
πŸ“Bordeaux (France)🍷
πŸ“ Registration opens soon

frontiersneurophotonics.org

03.02.2025 09:23 β€” πŸ‘ 10    πŸ” 7    πŸ’¬ 5    πŸ“Œ 2
2025 Speakers – International Frontiers in Neurophotonics Symposium

Save the date !
Frontiers in Neurophotonics Symposium 2025 in Bordeaux
October 6-9
frontiersneurophotonics.org/2025-speakers/
πŸ§ͺ

05.02.2025 14:08 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 0    πŸ“Œ 2
Post image

#MiFoBio2025

The autumn microscopy school by @gdrimabio.bsky.social will take place from 10th to 16th October 2025.

The call for workshops to share pratical knowledges is open till 31/01 ateliers-mifobio.fr

We'll bring stuff as usual, stay tuned !

More information πŸ‘‰ linktr.ee/gdrimabio

20.01.2025 11:26 β€” πŸ‘ 13    πŸ” 7    πŸ’¬ 1    πŸ“Œ 2
Post image Post image

Seems like there is a new ultracompact #femtosecond #laser source for #multiphoton #microscopy in town! 50 MHz rep rate means a 2-3 m cavity if there is a single pulse circulating in the cavity - folding that into that compact of a form factor is quite impressive!
www.laseratwork.com/products-ove...

27.01.2025 07:50 β€” πŸ‘ 6    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

An Open-Source Joystick Platform for Investigating Forelimb Motor Control, Auditory-Motor Integration, and Value-Based Decision-Making in Head-Fixed Mice https://www.biorxiv.org/content/10.1101/2025.01.23.634598v1

24.01.2025 03:15 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1
Video thumbnail

The AODscopeHUB! It makes the two-photon imaging system as versatile as you need: double the imaging setup, while using the same scanner and detection system! An ideal solution for an imaging facility and multi-user environment

23.01.2025 16:28 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex Responses to local and global violations in sound sequences are prediction errors and not simply the consequence of stimulus-specific adaptation.

Catching up from the dead time w/o X, here is the excellent recently published study by Sara Jamali with @standehaene.bsky.social using the local-global prediction paradigm in mice. Oddball signaling is not just adaptation. Sequence chunking responses in VIPs. And some more doi.org/10.7554/eLif...

19.01.2025 17:15 β€” πŸ‘ 11    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Post image

Interested in understanding how things work? In particular the tools you use to study the brain? Join us at TENSS 2025 where we brainstorm ideas, build and debug microscopes, electrophysiology and behavior rigs amidst the picturesque Transylvanian hills! tenss.ro
Apply by: February 16th!

14.01.2025 04:58 β€” πŸ‘ 59    πŸ” 39    πŸ’¬ 2    πŸ“Œ 5
Paris NeuroCourse | Optical Imaging and Electrophysiological Recording in Neuroscience

Applications to the 2025 Paris Spring School in Optical Imaging and Electrophysiological Recording in Neuroscience (AKA the Paris Neuro Course) are now open. Deadline on the 1st of February.

The course will run 14-27 May 2025.

parisneuro.ovh

22.12.2024 14:34 β€” πŸ‘ 12    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0