Charlotte Lewis

Image of a herpesvirus structure

I am excited to share our latest preprint - An evolutionarily divergent herpesvirus with a giant tail. Featuring symmetry breaking and genome annotation from structure using ModelAngelo. doi.org/10.64898/202...

Very excited to share our work, a fish herpesvirus' cryo EM structure. It features a long PVAT tail, with new and host-like proteins discovered using modelAngelo, Dali, and Viro3D, including a host-like macrodomain
doi.org/10.64898/202...
@dbhella.bsky.social @grovearmada.bsky.social

A data figure showing a phylogenetic tree of H3N2 with 2025-K highlighted, the structure of the HA trimer with mutations characteristic of K highlighted, and box and whisker plots showing % neutralisation of the 2022 H3N2 vaccine strain, and of 2025 clade K, by various human antisera

🚨New Pre-Print🚨
Although H3N2 subclade K has multiple mutations in HA, neutralisation assays with pre-epidemic human sera show only moderate antigenic drift, and vaccines used in the 2024/2025 flu season induced cross-neutralising immunity
www.medrxiv.org/content/10.6...

Graphic that says NOROVIRUS: YOU DON'T WANT IT. It has a figure on hands and knees with effluent coming from both ends.

Never a good sign when I have a chance to post this.

www.usatoday.com/story/travel...

Join @uofglasgow.bsky.social for a funded 3.5 year PhD programme:

www.gla.ac.uk/colleges/mvl...

Also up for grabs is a project on antiviral PROTACs, supervised by us and the France lab (School of Chemistry) should ubiquitin and viruses appeal! Please get in touch with any questions.

Text box reading: Vaccines do not... do not overload or weaken the immune system – it's safe to give children and adults several vaccines at a time and this reduces the amount of injections needed do not contain mercury (thiomersal) do not contain any ingredients that cause harm – only ingredients essential to making them safer and more effective and only in very small amounts do not cause autism – studies have found no evidence of a link between the MMR vaccine and autism

Should you find yourself - for whatever reason - looking for a new set of authoritative, accessible summaries of the risks and benefits of vaccines to share with people, the NHS website is still doing a good job at this www.nhs.uk/vaccinations...

Alcohol-based hand sanitizers do not kill norovirus. Washing hands with soap and water is the way to go.

https://www.sciencenews.org/article/norovirus-vomiting-diarrhea-vaccine

Congratulations Spyros!!!

Taxonomic expansion and reorganization of Flaviviridae - Nature Microbiology Analysis of RNA polymerase hallmark gene phylogenies supported by protein structure relationships of flaviviruses and ‘flavi-like’ viruses underpins the taxonomic expansion and reorganization of Flavi...

🧬 Thrilled to share our latest paper in @natmicrobiol.nature.com 📄

A collaboration to give the Flaviviridae (home to Zika, Dengue & HCV) a much-needed taxonomic re-think.

Our at-scale AI structure prediction gave a complementary perspective on viral evolution.

www.nature.com/articles/s41...

Really cool stuff! Congratulations Dan!

Norovirus Outbreak Sickens Nearly 100 on Royal Caribbean Cruise

My nightmare: “Almost 100 people came down with norovirus aboard a Royal Caribbean ship amid a 13-day voyage, the Centers for Disease Control and Prevention reported earlier this week… The first reports of illness were made on Sept. 28, with four crew members and 94 guests falling ill”

Well done Emma!! Amazing stuff!

I am delighted to share this preprint describing the structure and transcriptomics analysis of adenovirus D10 - a fantastic collaboration - and a lot of hard work by Kasim and Rosie.

Had a brilliant time at the 9th International Calicivirus Conference in Banff (www.calicivirusconference.com) - phenomenal science in a phenomenal setting! It was great to present my PhD work so far (thanks @dbhella.bsky.social for the pic). Here's to many more!