Mari B. Gornitzka's Avatar

Mari B. Gornitzka

@maribgo.bsky.social

PhD student @ University of Oslo | I like ripped genes, long genes, baggy genes and double genes

54 Followers  |  137 Following  |  1 Posts  |  Joined: 27.11.2024  |  1.427

Latest posts by maribgo.bsky.social on Bluesky

*constant*ly amazed 🧬

14.02.2025 09:17 — 👍 2    🔁 0    💬 0    📌 0
Preview
Ultra-long sequencing for contiguous haplotype resolution of the human immunoglobulin heavy chain locus Genetic diversity within the human immunoglobulin heavy chain (IGH) locus influences the expressed antibody repertoire and susceptibility to infectious and autoimmune diseases. However, repetitive seq...

Check out long-read sequencing results in human IGH! HUGE duplications in constant gene regions...and 7 copies of IGHV3-23 on one haplotype! @lossiusandreas.bsky.social @williamlees.bsky.social

www.biorxiv.org/content/10.1...

18.12.2024 15:20 — 👍 27    🔁 13    💬 1    📌 1

Our collaborative paper on #Nanopore sequencing is now available on #BioRxiv. Among several new variants, we characterize a large duplication in the IGHC region, suggesting non-canonical class switching between the duplicated isotypes in #Bcells.
www.biorxiv.org/content/10.1...

18.12.2024 10:08 — 👍 5    🔁 3    💬 0    📌 0

@maribgo is following 20 prominent accounts