Protocol for targeted gene manipulation and thermogenic evaluation in mouse brown adipocytes
Adeno-associated viruses (AAVs) are versatile, non-integrating vectors for in vivo gene delivery. We present a reproducible workflow for generating Crβ¦
In @cp-starprotocols.bsky.social we present a protocol for generating and targeting Cre-dependent FLEX-AAVs in vivo, for the assessment of #thermogenesis in brown #adipocytes using #respirometry.
@mcgillgci.bsky.social
Link hereπ
www.sciencedirect.com/science/arti...
30.12.2025 06:51 β
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LinkedIn
This link will take you to a page thatβs not on LinkedIn
Canada Impact+ program. Recruiting across Canada at all career stages:
-Postdocs (lnkd.in/gen4g-mp)
-senior Research Chairs or Emerging Leaders (lnkd.in/gyVs2UH3)
27.12.2025 03:08 β
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Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer
Nature Genetics - Analysis of 14,106 tumor genomes highlights recurrent mutations in mitochondrial ribosomal RNA encoded within the mitochondrial genome. Mutations occur at hotspot positions and...
Excited to share our latest work in collaboration with the @edreznik.bsky.social lab @mskcancercenter.bsky.social, where we describe functionally dominant mitochondrial DNA mutations in patient tumors. So, what is functional dominance in mitochondrial genetics, I hear you ask?
rdcu.be/eN1jm
03.11.2025 11:14 β
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Redirecting
Creatine fuels cancer. In @asbmbjournals.bsky.social we show CKB drives CK activity in NSCLC, osteosarcoma & ovarian cancer, promoting metastasis & anoikis resistance. Led by postdoc Mouna Tlili, in collaboration with Peter Siegel + @mcgillgci.bsky.social. Preproof: www.jbc.org/article/S002...
12.10.2025 01:51 β
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Massive congratulations to newly minted Dr. Jakub Bunk for passing his PhD defense with flying colours. Looking forward to seeing your scientific progress. We will miss you! @mcgillgci.bsky.social
09.10.2025 23:19 β
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Congratulations to our distinguished awardees at the inaugural #asiposebiology conference: Bruce Spiegelman, Yu-Hua Tseng, and Paul Cohen.
Your work continues to inspire and shape the future of our community
#ABC2025 @adiposebiology.bsky.social @sablesys.bsky.social @spiegelmanlab.bsky.social
22.08.2025 05:15 β
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FINALLY! π₯ See you all TOMORROW, Monday August 18th at 17:00 for early registration and cocktails. Download the full #AdiposeBiology Conference program here: adiposebiology.com/program
Get ready for #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
17.08.2025 17:47 β
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Just ONE WEEK until the #AdiposeBiology Conference! See you in Montreal! Check our website for details and the full schedule: adiposebiology.com #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
12.08.2025 15:10 β
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LAST CALL! The deadline to register, submit your abstract, and apply for a travel award is TOMORROW August 1st for the #AdiposeBiology Conference, happening in Montreal NEXT MONTH. Secure your spot now at adiposebiology.com! #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
31.07.2025 14:35 β
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Happy 107th Birthday, Brenda Milner! Her contributions to neuropsychology shaped the way we understand the human brain. From surviving two world wars and two pandemics, to paving the way for future generations of researchers, Milnerβs legacy continues. @mcgill.ca @cusm-muhc.bsky.social
15.07.2025 14:05 β
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New paper from Jakub Bunk in our lab: CKB is the key creatine kinase driving UCP1-independent thermogenesis in beige fat via the futile creatine cycle (FCC). doi.org/10.1016/j.mo...
@mcgillgci.bsky.social @biochehling.bsky.social
04.07.2025 02:51 β
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(EN) For its 20th anniversary, @cp-cellmetabolism.bsky.social is spotlighting researchers who defined the field of metabolic science. Featured is @kazaklab.bsky.social, GCI Researcher, recognized for postdoctoral work on creatine metabolism. Article: tinyurl.com/mfdbakyz
27.06.2025 12:00 β
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LAST CALL! Deadline to be considered for a SHORT TALK is TOMORROW July 1st, for the #AdiposeBiology Conference happening in Montreal, Aug 19 & 20th, 2025. Go to: adiposebiology.com to SUBMIT YOUR ABSTRACT TODAY! #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
30.06.2025 15:19 β
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If you donβt have time to take a walk, then you donβt have time to do science. Charles Darwin would take two walks every day on his "thinking path", not as a break from science, but as a crucial part of it.
30.06.2025 08:19 β
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Home | Adipose Biology
Welcome to the inaugural Adipose Biology Conference hosted in Montreal, Canada on August 19th - 20th 2025.
Speaker Spotlight: Mikael RydΓ©n @ki.se
Join us @ the #AdiposeBiologyConference in Montreal π¨π¦, Aug 19β20, 2025, to hear from this expert!
πWant to speak? Submit your abstract by July 1, 2025 at: adiposebiology.com
@mcgillgci.bsky.social @sablesys.bsky.social @adiposebiology.bsky.social
24.06.2025 16:55 β
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Canβt wait Joeva!!
10.06.2025 21:34 β
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So excited to present our work at the Goodman Cancer Institute at McGill University this week. I am looking forward to connecting with all the excellent scientists at McGill. Thanks @kazaklab.bsky.social for the invite!
10.06.2025 21:26 β
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π₯ Almost 100 registrations for the inaugural #AdiposeBiology Conference in MontrΓ©al!
Join us Aug 19β20, 2025 for cutting-edge science & community.
πRegister: adiposebiology.com/registration
@mcgillgci.bsky.social @uoft.bsky.social @sablesys.bsky.social
@sunglab.bsky.social @beaudrj.bsky.social
04.06.2025 15:08 β
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Pitching in: Raising millions for cancer research in honour of Terry Fox
Terryβs younger brother, Darrell Fox, plans to cycle across Canada for the National Ride of Hope, making stops along the way in several communities
Darrell Fox to bike across Canada in honour of his brother Terry, hoping to raise another $1-million for #cancer research (@terryfoxfoundation.bsky.social has already raised $900-million), by Paul Waldie
www.theglobeandmail.com/business/art... via @theglobeandmail.com @terryfoxresearch.bsky.social
01.06.2025 13:15 β
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LAST CALL! Early Bird Registration Deadline is THIS SUNDAY June 1st, for the #AdiposeBiology Conference happening in Montreal, Aug 19 & 20th, 2025. Go to: adiposebiology.com to secure your spot TODAY! #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
30.05.2025 21:29 β
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Congratulations to Jakub Bunk for passing his senior seminar!!!!
26.05.2025 19:29 β
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LAST WEEK! Early Bird Registration Deadline is June 1st, for the #AdiposeBiology Conference happening in Montreal, Aug 19 & 20th, 2025. Go to: adiposebiology.com to secure your spot TODAY! #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
26.05.2025 14:09 β
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Congratulations to @kazaklab.bsky.social and their collaborators for this new publication in @naturecomms.bsky.social!
04.04.2025 18:16 β
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Thanks to sponsorship for the #AdiposeBiology Conference, Montreal, Aug 19 & 20, 2025, weβre offering #travel and #science awards to trainees + new #LeslieKozak & #JeanHimmsHagen speaker awards!
Register @: adiposebiology.com
@sablesys.bsky.social @beaudrj.bsky.social @mcgillgci.bsky.social
09.05.2025 15:16 β
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Thanks to the AMAZING interest and registrations, we are able to EXTEND EARLY BIRD to June 1st!
#AdiposeBiology Conference Montreal, Aug 19 & 20th, 2025.
Go to: adiposebiology.com to secure your spot TODAY! #ABC2025 @kazaklab.bsky.social @beaudrj.bsky.social @sunglab.bsky.social
06.05.2025 00:24 β
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Congratulations to our very own Maria Guerra for securing a 4 year @FRQNT #PhD fellowship!! @mcgillgci.bsky.social
01.05.2025 20:46 β
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