Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: www.biorxiv.org/content/10.1...
01.08.2025 15:27 β π 69 π 25 π¬ 4 π 2
Congratulations Girish and team! ππ
31.07.2025 19:41 β π 2 π 0 π¬ 1 π 0
Sub-3 Γ
resolution protein structure determination by single-particle cryo-EM at 100 keV
Cryoelectron microscopy (cryo-EM) has transformed structural biology by providing high-resolution insights into biological macromolecules. We report sβ¦
Now out in Structure: Paper on high-resolution #cryoEM using the 100 kV Tundra cryo-TEM by Dimple Karia, Adrian Koh, @abhaykot.bsky.social, @lingboyu.bsky.social, @landerlab.bsky.social and many others. Happy to have contributed to this effort. Check it out:
www.sciencedirect.com/science/arti...
30.07.2025 21:50 β π 76 π 37 π¬ 1 π 0
π¨π¦π¨Job alertπ¨π¨π¦
We're looking for a senior scientist (program head) in the developmental, stem cell, and cancer biology program at the Hospital for Sick Children
25.07.2025 19:21 β π 5 π 5 π¬ 0 π 0
An inspiring read. Thank you sharing your journey Francesca!
23.07.2025 17:44 β π 1 π 0 π¬ 1 π 0
π’ For all HaloTag loversπππβ€οΈππ©Ά we are excited to share that our work, in which we developed a new biotin-HaloTag ligand, is now published in @jcb.org! Full link here: rupress.org/jcb/article-...
23.07.2025 10:10 β π 41 π 11 π¬ 1 π 0
π so much inspiration in one photo
17.07.2025 22:06 β π 9 π 1 π¬ 1 π 0
Postdoc in Structural Biology of RNA processing complexes
Postdoctoral positions in structural biology of macromolecular complexes are available in the laboratory of Dr. Eva Kowalinski at the EMBL Grenoble, France. We are looking for highly motivated and amb...
Postdoc positions in structural biology of RNA processing complexes.
An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification.
Details: tinyurl.com/postdoc-RNA-...
17.07.2025 09:50 β π 20 π 19 π¬ 0 π 1
Research Group Leader in Chemical/Synthetic Biology at MRC Laboratory of Molecular Biology
Start your UK & international job search for academic jobs, research jobs, science jobs and managerial jobs in leading universities and top...
We are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).
14.07.2025 12:09 β π 21 π 21 π¬ 0 π 3
Our entrance into protein design! Inverse folding steered by external sources of information, and for multiple conformations. By the amazing @kaiyi94.bsky.social and @kjamali.bsky.social!
Download our code and try it yourself. π₯³
15.07.2025 07:18 β π 32 π 10 π¬ 2 π 0
Excited to share that our latest story on Restrictor is out now in @genesdev.bsky.social!! Big thank you to my fellow co-first author Hanneke, Karen @adelmanlab.bsky.social and co-authors Nathalie and Allison!
14.07.2025 14:57 β π 30 π 12 π¬ 1 π 0
Indeed. Serendipitously we found it. Science always brings new surprises.
11.07.2025 14:10 β π 1 π 0 π¬ 0 π 0
Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.
11.07.2025 10:22 β π 59 π 17 π¬ 1 π 0
Sjors Scheres
Excellent opportunity for a postdoc to join @sjorsscheres.bsky.social in the LMBβs Structural Studies Division to work on #cryoEM structure determination of amyloid filaments in a lively, multi-disciplinary group.
Read more: www.nature.com/naturecareer...
Closes 03 AUG
#PostdocJobs #ScienceJobs
07.07.2025 08:28 β π 21 π 16 π¬ 0 π 1
Great opportunity for a Research Support Officer to join @cellbiol-mrclmb.bsky.social, supporting @deriverylab.bsky.social in their studies of the molecular mechanisms behind receptor sorting in endosomes.
More info: www.nature.com/naturecareer...
Apply by 10 JUL
#ScienceJobs
23.06.2025 15:11 β π 17 π 9 π¬ 0 π 0
Very cool structures. Congratulations Bettina!
26.06.2025 08:48 β π 1 π 0 π¬ 0 π 0
Our paper on Lymphostatin is now out (rdcu.be/etk2v). It shows #cryoEM structures of this huge virulence factor revealing amazing domain reorganisations.
Very enjoyable collaborating with the Stevens Lab in Edinburgh and the Boersch Lab in Jena to see how it gets into cells.
@uni-wuerzburg.de π§ͺβοΈ
25.06.2025 15:59 β π 26 π 7 π¬ 0 π 1
Joe Greener
Excellent opportunity for a postdoc to join @jgreener64.bsky.socialβs group at the LMB.
Youβll help develop novel molecular simulation methods to optimise sequences for diverse design tasks in computational protein design.
See: www.nature.com/naturecareer...
Apply by 13 JUL
#PostdocJobs #ScienceJobs
25.06.2025 13:49 β π 6 π 4 π¬ 0 π 0
Congratulations Zoe! ππ
25.06.2025 18:34 β π 1 π 0 π¬ 1 π 0
Deeply touched and honored by the Universidad AutΓ³noma de Madrid, my alma mater, (@uam.es) making me Doctor Honoris Causa. Thank you to the Department of Physical Chemistry for nominating me for this recognition. It was a memorable day for me and my familyπ©βπ
24.06.2025 19:53 β π 40 π 3 π¬ 0 π 0
Like a dream, my name next to that of @isabelallende.com, and to be recognized by Universidad Internacional MenΓ©ndez Pelayo UIMP. Soon after, Irene Vallejo @irenevalmore.bsky.social will receive the same honor. I feel proud to be linked to these truly inspiring, talented women! Thank you UIMP!
24.06.2025 17:03 β π 14 π 2 π¬ 1 π 0
A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie
π¨ JOB ALERT π¨
We're hiring a Research Assistant β no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired π§«π¬
Apply now π www.nature.com/naturecareer...
#STEMCareers #ResearchJobs
23.06.2025 13:00 β π 47 π 32 π¬ 1 π 5
Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAphi
Out in @pnas.org
Congrats @janboehning.bsky.social @abultarafder.bsky.social Miles Graham @mathieucoureuil.bsky.social
@mrclmb.bsky.social @hopitalnecker.bsky.social
www.pnas.org/doi/10.1073/...
23.06.2025 10:25 β π 55 π 17 π¬ 1 π 1
Thank you Hana. I hope you are doing well.
23.06.2025 12:49 β π 1 π 0 π¬ 1 π 0
Sad that I canβt be there. I hope it was fun as always.
21.06.2025 08:04 β π 2 π 0 π¬ 0 π 0
Prof & Lab Head in NYC. 100% research: cell division, genome integrity, cancer.
Curious to a fault. Also ΟΞΏΞ»ΟΟΟΞΏΟΞΏΟ. Talking here for me alone. I listen to the finest worksong. Like/repost = bookmark/news, not agreement/endorsement.
Taking care of Electron Microscopy @mpibp.bsky.social. Yay for #cryoEM and #cryoET βοΈπ¬but frozen is not always better. Also, #viruses π¦ rule.
Group leader @mpi_nat, GΓΆttingen, DE, exploring mechanisms of membrane trafficking. Cryo-EM, Cryo-ET, structural biology, cell biology.
All opinions are my own.
Structural biochemist and cryo-EM lover.
Research group leader at Human Technopole working on imaging thyroid biology across scales
website: https://humantechnopole.it/en/research-groups/coscia-group/
Professor | Gene Center @ LMU Munich
Cellular responses to DNA and RNA damage
Assistant Prof at Utrecht University, studying the process of transcription elongation vs early termination. (she/her)
RNA detectives on a mission to catch RNA in the act of folding & uncover how proteins helped. Run by graduate students / postdocs. Dr. Sarah Woodsonβs Lab at Johns Hopkins University.
Postdoc at the FMI (@fmiscience.bsky.social) in Basel, interested in chromatin, biochemistry and SINE transposons
RNA decay, RNA sorting, gene expression
I am an Assistant Professor of Cancer Biology at Loyola University Chicago Stritch School of Medicine (www.fanninglab.com). The Fanning lab studies how allostery governs estrogen receptor-dependent transcriptional programs in breast cancer.
Group Leader and Lecturer at the Australian National University | researching bacterial thiol redox pathways and virulence factors | community builder | storyteller | views my own | she/her
Assistant prof at UCI School of Medicine | Molecular mechanisms of gene editors & Engineering precision editing tools to fix genetic diseases | CRISPR, structure, biochemistry
Interested in all things, passionate about a few. π¬πͺ±π§¬π¦ PhD working in pharma. Spent a decade abroad in π¨π³πΈπ¬π¬π§, now back in πΈπͺ. Centerpartist. He/Him.
Pathogen entry into cells, host immune responses & vaccine design: structural biology, protein design, virology & immunology @hhmi.bsky.social
@uofwa.bsky.social
Computational Chemistry and Biology Lab; Proteins and Small Molecules; Always Room for Improvement.
Dept. of Chemistry, University of Pavia, Italy
Professor at the University Medical Center GΓΆttingen & Group Leader at the MPI for Multidisciplinary Sciences
Structural biology of gene expression
https://hillenlab.uni-goettingen.de
Director CUNY ASRC Structural Biology, Prof CCNY Chemistry & Biochemistry plus GC PhD programs. Studies nature's sensors and uses them to control biology; builds new academic & industry culture. Opinions are solely my own.
Principal Group Leader at the Francis Crick Institute. DNA replication, cryo-EM and molecular mechanism.
