Anay Kumar Maurya

Congratulations 🥳

Short graphical abstract summarizing key facts about Angomonas: its habitat in the digestive tract of insects; the cellular organization of the flagellate containing a single cytoplasmic endsymbiont with associated glycosomes; synchronized cell cycles of host and endosymbiont; the discovery of endosymbiont-targeted host proteins (ETPs) by mass spectrometry; differential subcellular localization of the ETPs; and the endosymbiont division machinery of dual genetic origin.

The symbiont-harboring trypanosomatid Angomonas deanei is Parasite of the Month. 🙂
authors.elsevier.com/sd/article/S...

A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

✨ I am thrilled to share ✨ that our paper on computational biosensor design has just been published!

Huge thanks to all co-authors and collaborators for the great teamwork and dedication throughout this journey! 🙌

📄 Read the paper here:
pubs.acs.org/doi/10.1021/...

On this day in 2021, I landed in a snowy, lockdown-silenced Heidelberg to start my lab. 5 years later we are a force to reckon with in our field, and the first generation are striking out on their own. I couldn’t be more proud, & grateful to them and our wonderful collaborators around the world 🌍 🧪

Congratulations💐, Christine. Well deserved 👏

Finally out – It is all about cholesterol
Thanks to all for this excellent collaboration

Thanks for sharing Philippe, nice to see Julius there.😊

The exceptional Julius Lukes gave a great talk @pasteur.fr today making sense of non-sense #parasites!

Postdoc (m/f/d) in Endosymbiosis Research

📢Postdoc position available!🧪🧫🧬
Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions.
Full details & application: karriere.hhu.de//index.php?a....
Please help us get the word out!

Applause to Victoria Klimenko and huge thanks to @sander1507.bsky.social and the whole HHU Center for Structural Studies team for an amazing collaboration!🥳🥳🥳 (2/2)

crTP X-ray structure

✨X-ray crystallography reveals surprising twist in how proteins enter the unique photosynthetic organelles of Paulinella. The chromatophore targeting peptide (crTP) folds into a 3D structure, hinting that folded proteins cross peptidoglycan and inner membrane. (1/2)
academic.oup.com/plphys/artic...

Great issue! Bonus: includes Daniel's work on incorporation of tagged tubulin in flagella!

Thanks, Gautam. This helps students reducing their level of demoralisation.😊

If you’re applying to your dream lab for an internship/PhD/postdoc, always send a second email 1-2 weeks after the first one if you don’t hear back.

I promise we will be grateful rather than annoyed. My email inbox is a disaster and I’m quite junior - and very few of us have secretarial support

Interesting!!❤️

Out today: New nucleus-encoded component of the endosymbiont division machinery identified in the trypanosomatid Angomonas deanei.
Congrats @anaymaurya.bsky.social and @rudycadenabioevo.bsky.social!!!🎉🎉🎉 1/2
journals.asm.org/doi/10.1128/...

Congratulations everyone 👏👏

In Angomonas, the host and endosymbiont divide in sync. We discovered that ETP2 helps recruit the dynamin-like protein ETP9 to the symbiont division site, revealing a new piece of the host-encoded machinery controlling endosymbiont division.
Beautiful artwork by @anaymaurya.bsky.social 2/2

Seconded! And if you can't review please suggest alternates. Early career folks are always welcome and lots of journals make it easy to co-review with a trainee.

If you're new and want reviewing opportunities make sure your Google Scholar, Scopus and ORCID etc are up to date so we can find you!

A black and white illustration depicting the changes in the immune system throughout an individual’s life span, from infancy to childhood, adulthood, and older age. There are blank labels 1–10 throughout the illustration.

An illustration depicting the changes in the immune system throughout an individual’s life span, from infancy to childhood, adulthood, and older age.

Can you can identify these 10 components featured on our Evolving Immunity special issue cover? 🔎

Drop your guesses in the comments. We’ll reveal the answers next week, so stay tuned!

Discover more about the special issue here: https://scim.ag/3JdpWYj

Congratulations, Daniel 💐

Discover more about our dear Daniel: journals.biologists.com/jcs/article/...
His paper can be found here
doi.org/10.1242/jcs....
Many thanks to @jcellsci.bsky.social for giving visibility to young scientists!

Congratulations to Megan Sørensen on receiving an FWF-ASTRA Award! We’re thrilled to announce that Megan Sørensen has been awarded a prestigious FWF-ASTRA grant to investigate at CeMESS how microbial partnerships have shaped evolution.

We’re thrilled to announce that Megan Sørensen has been awarded an FWF-ASTRA for her upcoming research at #CeMESS on microbial partnerships and evolution!

Read more about the grant and project 🔗 cemess.univie.ac.at/news/detail-...

Congratulations Megan💐👏

Congratulations Daniel and Philippe💐

Daniel's paper is now published in @jcellsci.bsky.social, great experience with @reviewcommons.org 😀

Want to know everything tubulin assembly in trypanosome flagella and other microtubules? Here is the link:

journals.biologists.com/jcs/article/...

We are looking for a postdoc with experience in electron microscopy.
mail to ruediger.simon@hhu.de

A gatekeeper for gene transfers - Nature Plants Large-scale genetic screening for plastid-to-nucleus gene transfers identifies that fast double-strand break repair functions as a key barrier for nuclear integration of organellar DNA and provides in...

With their clever setup to visualize ongoing endosymbiotic gene transfers (EGTs), Enrique Gonzalez-Duran, Ralph Bock and team reveal how double-strand break repair limits excessive EGT. Check out their new Nature Plants paper and my News and Views summary! www.nature.com/articles/s41...

T7 RNA polymerase-based gene expression from a transcriptionally silent rDNA spacer in the endosymbiont-harboring trypanosomatid Angomonas deanei Eukaryotic life has been shaped fundamentally by the integration of bacterial endosymbionts. The trypanosomatid Angomonas deanei that contains a β-proteobacterial endosymbiont, represents an emerging ...

Excited to share that our T7 RNA polymerase-based expression system brings a new level of versatility to Angomonas deanei as a model for studying endosymbiosis!
doi.org/10.1371/jour...

Frontiers | The Mycotoxin Beauvericin Exhibits Immunostimulatory Effects on Dendritic Cells via Activating the TLR4 Signaling Pathway Beauvericin (BEA), a mycotoxin of the enniatin family produced by various toxigenic fungi, has been attributed multiple biological activities such as anti-ca...

..building on our previous Frontiers in Immunology paper 🔗 doi.org/10.3389/fimm...

#Immunology #CathepsinB #Mycotoxins #ProteinScience #Beauvericin

📖 Have a look and feel free to share!