Brian Sheridan Lab

I'll take #gdTcells for $500

US senators poised to reject Trump’s proposed massive science cuts Committee gives first hint that policymakers might preserve, rather than slash, funding for US National Science Foundation and other agencies.

A key US Senate committee has indicated that it will reject the huge budget cuts that President Donald Trump proposed for some science agencies, including the US National Science Foundation and NASA.

go.nature.com/40H0XST

As NIH budget deliberations continue, prepare to hear Bhattacharya deflect substantial questions about the negative effects of his funding policies with “I’m an economist.”

He’s not a very good one if he’s unable to assess the impact of funding decisions at the agency he directs.

Macrophages: sentinels, warriors, and healers Abstract. Macrophages are versatile innate immune cells that act as sentinels, warriors, and healers in virtually every tissue. This review synthesizes cur

Our latest review on macrophages Macrophages: sentinels, warriors, and healers url:https://academic.oup.com/hmg/article-abstract/doi/10.1093/hmg/ddaf087/8158008

academic.oup.com/hmg/advance-...

This is a great idea! I really enjoy the JI Pillar articles

Listen to our newest Immunology faculty @priyadevarajan.bsky.social discussing her new lab @stonybrookmedicine.bsky.social and the benefit of @societymucosalimm.bsky.social mentorship program to her career development!

Plot of life expectancy after Type 1 diabetes diagnosis, 1850-2025. After the discovery of insulin in 1921, life expectancies go gradually from zero to seventy years.

These are VERY rough estimates, but here's life expectancy after diagnosis of type-I diabetes over the past 150 years.

It was Banting and Best's discovery of how to isolate insulin in 1921 — not some fucking cooking class — that gave people including my daughter a new lease on life.

Government | Harvard University Browse the latest Government courses from Harvard University.

Proud of Harvard for pushing back, exercising some creativity, and, maybe, helping folks get some needed education.

Harvard is making many of their online government courses FREE.

I just signed up for "Citizen Politics in America".

They even asked me my Gender.

pll.harvard.edu/subject/gove...

Metabolic reprogramming of IL-17 producing gd T cells promotes de novo lipogenesis under psoriasis conditions

NEW: We (mostly @noamross.net) launched a website to shine a brighter light on terminated NIH and NSF grants.

grant-watch.us

It links to our NIH & NSF trackers, grant info submission forms, and other info. We'll also add new analyses soon.

Check it out and let us know what else you'd like to see.

Biomedical Research: Keeping America’s Edge in Innovation | United States Senate Committee on Appropriations United States Senate Committee on Appropriations

www.appropriations.senate.gov/hearings/bio...

Check out this cool new study from a colleague at @stonybrookmedicine.bsky.social. Congrats to Charles and his team! Mtb-reactive CD8a expressing NK cells in humans!

Another great study from the @khannakm.bsky.social lab! Disease tolerance to limit Pathology in mucosal tissues

Check out this fantastic story from @ikinglab.bsky.social group! There's always something cool going on in the mucosa

NIH cancels its first and largest study centered on women The Women’s Health Initiative has produced numerous influential findings

I don't get how anyone can possibly be okay with ending the WHI. This study has accrued decades of data from 42000 women and it is still going. It helps to address critical research gaps that have been allowed to go unfilled because of durable misogyny and provides invaluable insight into aging.

From South America to the global stage!

Meet Dr. Eduardo Villablanca and Gustavo Monasterio Ocares as they share how SMI has supported their efforts to increase opportunities for mucosal immunologists in South America.

Watch here: www.socmucimm.org/about/smi-or...

#MucosalImmunology

gavage with Listeria leads to rapid (within 4 hour dissemination to the liver) but feeding takes 48 hours and appears to pass through the MLN. We thought this was a technical limitation of gavage but perhaps it's different with Yersinia.

Thanks for sharing and best of luck with submission!

Okay, that sounds great. So, how do you think this works? The ole direct access to the hepatic portal vein? Shouldn't that require pass through though? We've been struggling with these questions in the Listeria system for some time. But...

Very cool study! Curious if you looked at foodborne infection instead of gavage using this approach to compare splenic/liver vs intestinal founders?

Will do. Just switched over from the other place a few weeks back.

Thanks Laura 😊
Hope all is well at UConn!

This chart seems to suggest that something is going wrong in the United States, specifically.
(www.ft.com/content/7568... )

How a PhD student’s lab size affects their chance of future academic success Trainees in big research groups tend to go on to greater academic success than their small-group counterparts ― but are more likely to quit academia altogether.

Postdoctoral students, graduate students and other junior scientists in large research groups are more likely to drop out of academia than are their peers in smaller groups, says a study of more than one million early-career researchers.

https://go.nature.com/3F8sZyV

Congrats Jie and team!

Navy background with white text that says "2 days until stand up for science"

2 DAYS until we STAND UP FOR SCIENCE!

More information on local sites available at www.standupforscience2025.org ☀️

#standupforscience2025

We are experiencing an assault on science unparalleled by anything I’ve seen in my life. It’s not one issue or another anymore, the entire institution is under attack by the most powerful individuals in the country.

This Friday, where will you be?

standupforscience2025.org

Make it make sense!

Inside the Collapse at NIH Administration officials pressured NIH to avoid clear advice from the agency’s own lawyers to restart grant funding now.

I talked to NIH officials, current and former, about what's been happening inside the agency since the Trump administration shut down their grantmaking pipeline in January. Their stories showed just how willing our new leaders are to break the law: www.theatlantic.com/health/archi...

Deactivated my Twitter account! I feel so much cleaner...