Steve Kelly

OrthoFinder just dropped a major update

It’s faster, more accurate, and ready for thousands of genomes

Let’s break it down (1/10)

github.com/OrthoFinder/...
www.biorxiv.org/content/10.1...

New ARIA award will aim to deliver a revolution in sustainable Researchers in the University of Oxford’s Department of Biology and Wild Bioscience Ltd are to receive backing of a £6.7 million grant from the Advanced Research and Invention Agency (ARIA) to

Researchers in @biology.ox.ac.uk and Wild Bioscience Ltd are to receive backing of a £6.7 million grant from the Advanced Research and Invention Agency (ARIA) to pioneer a new synthetic biology approach which promises to improve yields in potato and wheat.

Read more ⬇️ #OxfordClimate

So true: "In a very short time, we have created not only silly systems of governance and regulation, but are also managing to subvert academic life through the creation of bullshit jobs and, I would argue, bullshit practices."

Thank you! ☺️

Second writeup! This paper made me fall back in love with photosynthesis evolution. ❤️

Review: The complexities of metabolite transport in C4 photosynthesis | Plantae C4 photosynthesis, an adaptive mechanism to spatially concentrate CO2 around Rubisco to enhance carbon fixation, has evolved independently at least 60 times in plants. This process spatially…

Plant Science Research Weekly -- Review: The complexities of metabolite transport in C4 photosynthesis (The Plant Cell) @stevenkelly.bsky.social (Summary by Mae Mercado @maemercado.bsky.social‬ ) buff.ly/LyHf7qN

#PlantaePSRW

Images showing shape of hypocotyls (WT, phot1 and cry1) under dark or blue light, with the growth rate color-coded onto the tissue. The WT elongates in the dark, but not in the light. The phot1 mutant continues elongating under blue light, as does the cry1, but in cry1 the elongation is is a different location, closer to the cotyledons.

#PlantSci Research Weekly March 7 plantae.org/plant-scienc... Review: C4 metabolite transporters; Insights from Marchantia pangenome; cry1 & phot work synergistically; Plasmodesmata as MCS for intercellular communication; Developmental robustness from antagonizing cis-elements; (1/2)

@stevenkelly.bsky.social @pierremarcdelaux.bsky.social @dubcovskylab.bsky.social @williamsanu.bsky.social

Wild is hiring! If you’re passionate about making an impact in crop improvement using genomics and comp bio come join the team!

jobs.recruit.charliehr.com/wildbioscien...

Lots of ✈️ traffic over Oxford today. Never seen so many before

Endopolyploidy in the Leaf Cells of Rhodes Grass (Chloris gayana Kunth) | International Journal of Plant Sciences: Vol 185, No 3 Premise of research. Endopolyploidy is the occurrence of different levels of ploidy in the cells of the somatic tissues of an organism. Although several cell functions have been associated with endopo...

In the May 2024 @ijpsjournal.bsky.social

Endopolyploidy in the Leaf Cells of Rhodes Grass (Chloris gayana Kunth)

Hidekazu Kobayashi, Takao Oi

www.journals.uchicago.edu/doi/full/10....

The first step on a path to C4 rice by genome editing ✂️🧬

www.biorxiv.org/content/10.1...

A preprint several years in the making…

A holistic review of metabolite transport in C4 photosynthesis. Current understanding, key gaps, future directions and new molecular blueprints for NAD-ME. A masterpiece by former PhD student Oliver Mattinson

ecoevorxiv.org/repository/v...

😂😂😂

A quick visit to my (scientific) roots today… haven’t changed a bit 😂😂😂

Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts https://www.biorxiv.org/content/10.1101/2024.02.14.580295v1 The ATP-driven bicarbonate transporter BCT1, a four-component complex in the cyanobacteria CO2-conce

Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts https://www.biorxiv.org/content/10.1101/2024.02.14.580295v1

A surprising discovery - a role for lineage in leaf development. Great work by @chiaraperico.bsky.social

The NHM was looking spectacular this evening 🦖

Musk’s Starlink satellite train just passed over Oxford.. satellites stretched horizon to horizon … I genuinely thought it was aliens!

Very pleased to have finally got this out there - many years work by the team - primarily Dana Vlad. Discovered that large vein ranks are actively repressed to allow smaller veins to develop. All grasses we looked at are the same. Allowed us to change patterns in rice - not quite C4 rice but closer

Never too late!

So it turns out that electroporation of exogenous DNA into organisms is entirely natural.

peerj.com/articles/165...

Exciting opportunity at the Queen’s College Oxford in association with @oxfordbiology.bsky.social. The Browne JRF is a three year independent research fellowship available in any area of biology that complements Oxford Biology.
www.queens.ox.ac.uk/vacancies/br...
Please repost!

Green branching shoots of Selaginella apoda

🚨Come join the lab🚨 to lead on developing Selaginella apoda as a genetic model system 🌿
1.5 yr PDRA, Deadline 13th Dec
Full details: elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

"People don't take climate action because they don't understand the science", someone said in a discussion yesterday.

But why do we treat climate science different than medicine? If people are told they have diabetes, they don't go "I don't understand the endocrine system, yum, cake" do they? 🧪

You could get the best of both worlds with SHOOT

www.shoot.bio

Awesome!

Nice!

Comparative analysis of gene regulatory networks identifies conserved regulators in seed plants bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Our prepring about comparative gene regulatory network analysis is available on bioRxiv! We focused on the regulation of C4 and C3 photosynthesis and identified conserved regulators for other pathways too. www.biorxiv.org/content/10.1... #Bioinformatics #generegulation #photosyntheis #PlantScience

The genetic basis of dynamic non-photochemical quenching and photosystem II efficiency in fluctuating light reveals novel molecular targets for maize (Zea mays) improvement https://www.biorxiv.org/content/10.1101/2023.11.01.565118v1 Maize is a major global crop species which uses C4 photosynthesis. Although C4 is typically consider

The genetic basis of dynamic non-photochemical quenching and photosystem II efficiency in fluctuating light reveals novel molecular targets for maize (Zea mays) improvement https://www.biorxiv.org/content/10.1101/2023.11.01.565118v1