Heilshorn Lab

Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and...

We're delighted to share our new work out in Advanced Science, led by PhD student Yueming Liu! We develop an in vitro model of nonalcoholic fatty liver disease to study the role of mechanosignaling in disease progression. Congrats to all!

🔗 doi.org/10.1002/advs...

End of the quarter means celebrating our awesome undergrads! Shout out to Hakim and Sanjana (pictured with mentors @chuerti.bsky.social and @dzhang17.bsky.social) for giving fantastic posters at the MatSci Spring Undergraduate Research Symposium! 🧑‍🔬

Congratulations to the newest PhD from the Heilshorn Lab, Dr. Yueming Liu! Yueming accomplished so much in her PhD, from dynamic modulation of engineered hydrogels to developing organoid models for studying liver disease. We are so proud! 😍

We are thrilled to be at #SFB2025 in Chicago this week! @vanessadoulames.bsky.social will be sharing some of our recent work on a hydrogel-mediated approach for spinal cord injury. Excited to see everyone! 🤗

We’re thrilled to be going to the APS Global Physics Summit this week in Anaheim! Don’t miss our talks by PhD student Diya and Prof. Heilshorn on biomaterials for 3D bioprinting and tissue modeling. 🙌 #APSSummit25 @apsphysics.bsky.social

📣 We are excited to share our new paper introducing a biofabrication strategy that directly generates branched, endothelial cell-lined networks using a diffusion-based, embedded 3D bioprinting approach:
iopscience.iop.org/article/10.1...

Led by Betty Cai in collaboration w/ Sungchul Shin!

A bittersweet goodbye to Dr. David Kilian as we send him off to the Netherlands! David will be joining the MERLN Institute at Maastricht University to start his independent research group! 🥳 We wish him the best and of course will miss him so much 🥺🫶

Interpenetrating networks of fibrillar and amorphous collagen promote cell spreading and hydrogel stability Hydrogels composed of collagen, the most abundant protein in the human body, are widely used as scaffolds for tissue engineering due to their ability …

📣 Excited to share our first manuscript of 2025 where we present an interpenetrating network of physically assembled collagen and covalently-crosslinked collagen, which contains *both* fibrous and amorphous #collagen networks!

Led by @luciabru.bsky.social & @chrislong42.bsky.social, check it out!

Organoid bioprinting: from cells to functional tissues - Nature Reviews Bioengineering Integrating bioprinting with organoid technology can enhance tissue engineering by improving complexity, reproducibility and scalability. This Review discusses living materials in bioprinting, current...

The biofabrication of human tissues requires a combination of engineering control and intrinsic self-assembly. In their Review, Sarah Heilshorn et al discuss how cells and organoids can be characterized as a living material and manipulated by biofabrication techniques go.nature.com/3ZJadEL

Happy holidays from the Heilshorn Lab! Great way to end the year celebrating each other’s accomplishments together 🤗🎄☃️

Organoid bioprinting: from cells to functional tissues Nature Reviews Bioengineering - Integrating bioprinting with organoid technology can enhance tissue engineering by improving complexity, reproducibility and scalability. This Review discusses...

Excited to share our new review on #organoid #bioprinting in Nature Reviews Bioengineering! 🎉 @natureportfolio.bsky.social

We highlight recent advances and envision a future that integrates organoid biology and biofabrication approaches to engineer complex tissues. Hope you enjoy!

🔓: rdcu.be/d3H6u

Hi 🦋! We are a biomaterials group at Stanford interested in tissue engineering, biofabrication, and hydrogel-based therapies. And we just celebrated labsgiving! 🤗🦃
#HiSky #SciSky