The Journal of Infectious Diseases

NAT2 polymorphisms and Antituberculosis-Induced Hepatotoxicity in Thai People Living with HIV: Insights from a Pharmacogenetic–Pharmacokinetic Cohort Study NAT2 slow acetylator phenotypes, especially *6A/*6A and *7B/*7B genotypes, significantly increase the risk of antituberculosis-induced hepatotoxicity in Th

NAT2 polymorphisms and Antituberculosis-Induced Hepatotoxicity in Thai People Living with HIV: Insights from a Pharmacogenetic?Pharmacokinetic Cohort Study

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Targeting Tryptophan Metabolism for Tuberculosis Biomarkers and Host Directed Therapy

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🔗 https://bit.ly/4mLDM2a

Serological Responses and Pregnancy Outcomes in Women With Serofast Syphilis: Efficacy of Retreatment in a Prospective Nested Case-Control Study There are inconsistencies in guidelines concerning the necessity for anti-syphilis retreatment during pregnancy for women who tested seropositive despite having received treatment before pregnancy. While global guidelines indicate that no further treatment is necessary...

Serological Responses and Pregnancy Outcomes in Women With Serofast Syphilis: Efficacy of Retreatment in a Prospective Nested Case-Control Study

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Household Molecular Epidemiology of Streptococcus pyogenes Carriage and Infection in The Gambia First molecular analysis of S pyogenes skin carriage in Africa. Skin carriage may be an important reservoir in RHD-endemic settings. · Highest strain diver

Household Molecular Epidemiology of Streptococcus pyogenes Carriage and Infection in The Gambia

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Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis: Data From the Experimental Model Daptomycin in combination with β-lactams significantly improves the activity of monotherapies in sterilizing valve vegetations and in preventing daptomycin

Time to Reappraise the Antibiotic Treatment for Methicillin-Susceptible Staphylococcus aureus Infective Endocarditis: Data From the Experimental Model

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A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin The standard of care of diphtheria is in critically short supply globally. We report here a phase 1 study of a human monoclonal antibody against diphtheria

A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin

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https://bit.ly/4nHpmBp

Did Horses Act as Intermediate Hosts That Facilitated the Emergence of 1918 Pandemic Influenza? Based on historical research of equine influenza epidemiology and horse movement data, we hypothesize that horses acted as intermediate hosts during the ge

Did Horses Act as Intermediate Hosts That Facilitated the Emergence of 1918 Pandemic Influenza?

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Mendelian Randomization and Infection: Pitfalls and Promises Mendelian randomization (MR) offers promise for infectious disease research but faces challenges. This update reviews MR principles, pitfalls specific to i

Mendelian Randomization and Infection: Pitfalls and Promises

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Insights on recurrent and sequential Clostridioides difficile infections from genomic surveillance in Minnesota, USA, 2019-2021

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🔗 https://bit.ly/46zgcB0

Effect of 5FU on paracoccidioidomycosis

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🔗 https://bit.ly/42kPKsd

Respiratory Virus Infections and Pulmonary Impairment after Allogeneic Hematopoietic Cell Transplantation.

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🔗 https://bit.ly/485qudb

Profiling Human Papillomavirus lineage-specific capsid antigenicity using geographically diverse natural infection antibodies

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🔗 https://bit.ly/46w3keP

Blood cultures contain populations of genetically diverse Candida albicans strains that may differ in echinocandin tolerance and fitness

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🔗 https://bit.ly/3Wk7W1y

Mechanistic insights into increased vulnerability to respiratory infections in HIV-Exposed Uninfected Infants

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🔗 https://bit.ly/4nxydpg

Seasonal variation and interspecies dynamics among Plasmodium falciparum and ovale species in Bagamoyo, Tanzania

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🔗 https://bit.ly/46LNrQ6

Real-world prevalence of non-integrase InSTI resistance-associated mutations and virological outcomes in people who have recently acquired HIV-1 in the UK Integrase strand transfer inhibitors(INSTIs) are the mainstay of antiretroviral therapy(ART) globally. Virological breakthrough is uncommon but often manifests as low level viraemia and only 50% of cases have identified drug resistance mutations in the integrase gene.

Real-world prevalence of non-integrase InSTI resistance-associated mutations and virological outcomes in people who have recently acquired HIV-1 in the UK

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🔗 https://bit.ly/4pIP2Pr

The major outer membrane protein P5 binds vitronectin to mediate serum resistance in non-typable Haemophilus influenzae

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🔗 https://bit.ly/4nRAGL1

The Changing Paradigm in Infectious Diseases - Host-Directed Medicine: Implications for the Next Generation of ID Physicians

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🔗 https://bit.ly/4nrIwey

The Pain is in the Brain with the Sugar-Coated Killer

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🔗 https://bit.ly/42LsTpP

Joint Call for Papers: Leveraging AI Technologies for Discoveries and Solutions in Infectious Diseases The IDSA journals are seeking papers focused on artificial intelligence (AI) and how it enhances and impacts infectious diseases. The journals are interested in

AI is transforming infectious disease research. JID seeks papers on host-microbiome interactions, antimicrobial discovery & pandemic preparedness. Submit by Nov 2.

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Maternal Inflammation Likely Drives Impaired Immune Responses to Respiratory Syncytial Virus in HIV-Exposed Uninfected Infants

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🔗 https://bit.ly/3VzGVXR

Adrenal corticosteroids and increased intracranial pressure in nonimmunocompromised patients with cryptococcal meningitis

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🔗 https://bit.ly/4nngkJx

Mesenteric ischemia and bacterial translocation precipitate the intoxication phase of yellow fever

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🔗 https://bit.ly/4nN5RXF

New JID supplement explores PEPFAR's infrastructure investments and their impact on global health security. Essential reading for global health policy experts and infection control professionals.

Available now ↪️ https://bit.ly/46mTcVG

Activin A mediated KAT8 expression induces ferroptosis during Mycobacterium tuberculosis infection

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🔗 https://bit.ly/4nfImH1

Mycobacterium tuberculosis PE_PGRS62 protein inhibits type I IFN responses to promote HIV-2 replication by directly interacting with IRF3

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🔗 https://bit.ly/3IcYDxf

Direct genome sequencing of Leishmania tropica in tissues of Moroccan patients with cutaneous leishmaniasis reveals micro-focal transmission underlain by (pseudo-)clonal and sexual reproduction modes.

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🔗 https://bit.ly/4nfIgPF

Investigating Azithromycin Activity Against ESBL-Producing Escherichia coli Under Physiologically Relevant Conditions

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🔗 https://bit.ly/3KAnbAM

Spontaneous Clearance of PCR-positive Plasmodium vivax Parasitemia in Northwestern Thailand: An Epidemiological Perspective

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🔗 https://bit.ly/48plLmI

Phylogenetic context of antibiotic resistance provides insights into the dynamics of resistance emergence and spread

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🔗 https://bit.ly/4nNjnLc