Jordi Casanova Mollà

Should we have a holistic wellness prescription for Parkinson’s? A committee from the Movement Disorders Society says YES in a new blueprint for living well. The word holistic: approach that considers the whole person: mind, body and social environment, rather than just individual symptoms.

🖥️En marxa la Guia d'especialistes de la #URV, un nou recurs que facilita el contacte entre la comunitat investigadora i els mitjans de comunicació.

👉https://diaridigital.urv.cat/es-presenta-guia-especialistes-urv/

AI-enabled eye tests to spot dementia or heart disease A UCL scientist is leading a new project using artificial intelligence (AI) to transform routine eye checks into tools for detecting early signs of conditions such as heart disease and dementia.

👁️ Professor Pearse Keane (@ucleye.bsky.social) to lead new project using AI to transform routine eye checks into tools for detecting early signs of conditions such as heart disease and dementia.
www.ucl.ac.uk/news/2025/se...

IA i cervell: una simbiosi que ens pot passar factura - El Diari de l'Educació Vivim envoltats de tecnologia que, cada cop més, “pensa” per nosaltres, però com està afectant la IA al desenvolupament cognitiu humà? Anem cap a una incompetència humana? D’entrada, cal reconèixer qu...

diarieducacio.cat/ia-i-cervell...

Why 7000 steps is the right number for Parkinson’s and beyond. What do I tell the folks in my clinic? The 3 D's: Death, Dementia and Depression. For years people have asked me how many steps they should aim for each day. New evidence: 7000 steps or their equivalent. @parkinsondotorg.bsky.social

Are we beginning to understand the conversations your brain is having during Parkinson's pain? Do we know why pain in Parkinson’s is different? Even people with Parkinson’s who say they are not in pain may still show abnormal brain pain responses. @sfn.org @parkinsondotorg.bsky.social

Un estudi de la #URV i l'@IISPereVirgili relaciona una major diversitat alimentària amb un menor risc de mortalitat en persones grans. Una dieta rica en diferents espècies vegetals i animals s’associa a una esperança de vida més llarga 👇
https://diaridigital.urv.cat/diversitat-dieta-risc-mortalitat/

Disruption of the cerebrospinal fluid–plasma protein balance in cognitive impairment and aging - Nature Medicine Proteomic analysis of paired cerebrospinal fluid and plasma samples from 2,171 individuals drawn from multiple cohorts, including the Global Neurodegeneration Proteomics Consortium, reveals age-related changes in the ratios of proteins in the cerebrospinal fluid and plasma that are associated with cognitive function, enhancing understanding of blood–brain barrier dynamics in aging.

Aging disrupts the brain barrier, revealing protein changes linked to cognitive decline and highlighting potential targets for new therapies.

by Farinas A, Rutledge J (...) Wyss-Coray T et 18 al. in Nat Med #MedSky

👉 get more here

📖 read the article:

It’s not just tremors in Parkinson's, we need to broaden our rehabilitation lens beyond balance and gait. We need strategies for sleep and autonomic symptoms like constipation, urinary and sexual dysfunction. We’ve long focused on movement, but what about the devastating non-motor symptoms in PD?

I am unbelievably proud to have my first senior author paper published today! It was a long slog through multiple review cycles but we got there!

A big thank you to my lab members and all the collaborators and participants who contributed to this work! 🥲

Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases - Journal of Neurology Promising blood-based biomarkers of neuropathology have emerged with potential for therapeutic development and disease monitoring. However, these tools will require specialist tertiary services for in...

New paper from the @hob-lab.bsky.social just published in Journal of Neurology. A step toward more accessible biomarker testing 🩸 link.springer.com/article/10.1... @drl-bo.bsky.social @uclbrainscience.bsky.social @uclqsion.bsky.social

Seeing the trees in the wood: the importance of co-pathologies in Alzheimer’s disease and dementia with Lewy bodies Our understanding of Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) owes a debt to pioneering work by Emil Kraepelin, Franz Nissl, Alois Alzh

I’m delighted to share my editorial for the July issue @brain1878.bsky.social academic.oup.com/brain/articl...

Do you have a plan for management of freezing of gait (FOG) in Parkinson's? I think about 5 things; nice paper in Nature Reviews Neurology.
1- Classify the type of FOG
2- Optimize dopamine
3- Use non-drug strategies
4- Treat the whole person
5- Think prevention

Sabench, Pallarès i Montserrat, a la Facultat de Medicina i Ciències de la Salut de la URV.

Un moment de la visita al campus Bellissens.

🎓La consellera de Recerca i Universitats visita la Facultat de Medicina i Ciències de la Salut de la #URV. El nou model de finançament, l’impuls de les titulacions STEM i de medicina i les infraestructures centren la trobada.

👉 diaridigital.urv.cat/la-conseller...

The future of Alzheimer’s treatment Drugs that clear away brain plaques are a welcome arrival, but targeting amyloid alone might not be enough to halt the disease.

In this @nature.com article, our VP Prof John Hardy reflects on how far Alzheimer’s research has come, and where it's heading next. A must-read for anyone working in neurodegeneration 👉 www.nature.com/articles/d41...

Human assembloid model of the ascending neural sensory pathway - Nature A human ascending somatosensory assembloid model was developed, which integrates multiple organoids to simulate the spinothalamic pathway, demonstrating functional connectivity and responsiveness to s...

www.nature.com/articles/s41...

In @nature.com today we report sensory #assembloids comprising four parts to recapitulate aspects of the pathway that processes pain stimuli and we use it to study genetic syndromes.
Work pioneered by the brilliant Ji-il Kim & Kent Imaizumi in close collab with @gregscherrer.bsky.social !
Link 👇

Does conventional spinal cord stimulation improve Parkinson's in the human? Insert nail in coffin. Dis aliter visum – the gods thought otherwise. A randomized crossover double-blind study says NO. Let's pivot to other approaches as Cury and colleagues enlighten us in the journal Movement Disorders.

The gut microbiota-immune-brain axis: Therapeutic implications The gut microbiota-immune-brain axis regulates key immune pathways influencing neuroinflammation and brain function. This review highlights how gut-immune communication impacts health and disease, emp...

Another amazing talk by @jfcryan.bsky.social on the relationship between microbiome and brain health (and disease): www.cell.com/cell-reports... #BrainConf2025

Giampiccolo et al. review the anatomy and function of the inferior fronto-occipital fasciculus, and propose that it plays a role in visual cognitive control based on perceptual features (dorsal layer) and conceptual content (ventral layer). https://buff.ly/41iuhjG

Striatal dopamine depletion in Parkinson's disease is linked to specific brain metabolism changes that influence motor and cognitive deficits.

by Yoo HS, Kim HK (...) Lyoo CH et 6 al. in Neurology #MedSky

📖 read the article: https://www.neurology.org/doi/10.1212/WNL.0000000000210105

Simple yet Effective: Scientists Identify Powerful Weapon in the Fight Against Alzheimer’s Aerobic exercise significantly lowers Alzheimer’s disease markers and improves brain health, offering a promising preventive strategy. Researchers plan human trials to validate these findings and explore...

Simple yet Effective: Scientists Identify Powerful Weapon in the Fight Against Alzheimer’s #Science #HealthandMedicine #Neurology #Alzheimers #Exercise #BrainHealth