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Alister Burt

@alisterburt.bsky.social

Computational Cryo-EM/ET at Genentech Love people, the outdoors and building stuff Complexity is the enemy All opinions my own

371 Followers  |  393 Following  |  214 Posts  |  Joined: 08.10.2023  |  2.6366

Latest posts by alisterburt.bsky.social on Bluesky

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Feudalism Is Our Future What the next Dark Ages could look like

An insightful read. I hadn’t appreciated the links between feudalism and privatization. The author’s evocation of how future historians may look back on our era in that respect felt important, and a fruitful way to think, to me. I’m hopeful the pendulum will swing back towards effective government.

11.10.2025 18:56 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
American Big Tech Has Enslaved Us | Aaron Bastani Meets Yanis Varoufakis
YouTube video by Novara Media American Big Tech Has Enslaved Us | Aaron Bastani Meets Yanis Varoufakis

Thanks for sharing Alexis, reading now - huge +1 on Tom’s recommendation, Varoufakis is also excellent in podcast form

youtu.be/VatYrw0uqjU?...

11.10.2025 22:04 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

We’ll have to compare, think mine is from the 70s

11.10.2025 21:27 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I’ll save your wallet by drip feeding recommendations going forwards πŸ˜‚

11.10.2025 17:24 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Veeeery nice! Enjoy it

11.10.2025 15:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Don Fawcett’s big red book The Cell is available for free online!!

There are a bajillion cryo-ET projects in there, recommend a physical copy if you can find one - it’s my favourite coffee table book

11.10.2025 15:42 β€” πŸ‘ 30    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Nice find!! Glad there’s a free digital copy out there - still recommend a physical copy if you can, I don’t have a coffee table but it’s my favourite coffee table book

11.10.2025 15:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

A small group of us bought the few used copies available on Amazon UK a few years ago, got to watch supply and demand do its thing live - hope you can find one for a good price!

11.10.2025 15:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

don’t have an answer for you but if you’re looking at cell tomograms often I can’t recommend Don Fawcett’s big red book The Cell highly enough - it’s a *beautiful* atlas of classic EM images

11.10.2025 15:25 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

Oooh no, will take a look!

11.10.2025 00:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is one thing the ML folks are doing right, the blog post + arxiv combo is all you (should) need, wish it was more normalised for bio too

10.10.2025 14:44 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Right! Anything powered by the source engine brings back such great memories πŸ₯°

10.10.2025 14:32 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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the GNE headcrab went for its latest victim today, a wild @sjorsscheres.bsky.social…

Thankfully @przemekdut.bsky.social was there to save the day!

10.10.2025 03:35 β€” πŸ‘ 20    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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A utopian future is still possible (just) Mainstream parties have stopped promising voters better lives

A utopian future is still possible (just) on.ft.com/46PEDsw | opinion

09.10.2025 10:07 β€” πŸ‘ 16    πŸ” 4    πŸ’¬ 3    πŸ“Œ 0
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Engineering substrate selectivity in the human sodium/iodide symporter (NIS) Iodide (I-) uptake mediated by the Na+/I- symporter (NIS) is the first step in the biosynthesis of the thyroid hormones, of which I- is an essential constituent. NIS couples the inward transport of I-...

1/9 πŸš€ Big news! As a result of 5 years of my PhD, building on a 30-year dream of my PI Dr. Nancy Carrasco, we think we've found a new way to treat cancer! We’ve released our preprint & I'm so excited to share this story! 🧡
www.biorxiv.org/content/10.1...
#Science #proteinengineering #proteindesing

09.10.2025 02:42 β€” πŸ‘ 5    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1

Egg, meet chicken

09.10.2025 03:58 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

so satisfying - question: are all the best microscopists Dutch?

09.10.2025 02:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Exploring White Light Interferometry!  (WLI / CSI)
YouTube video by Huygens Optics Exploring White Light Interferometry! (WLI / CSI)

Incredible video. I suspect I will end up watching every video on the channel.

09.10.2025 02:14 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
UK Set To Cave To Trump On NHS Drug Prices | #NovaraLIVE
YouTube video by Novara Media UK Set To Cave To Trump On NHS Drug Prices | #NovaraLIVE

It’s terrifying to watch the UK be so easily pushed into spending more on drugs…

youtu.be/_xdYrg3G_00?...

09.10.2025 01:59 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This has been a real pain point for Warp users since we moved to Linux, psyched to see it solved

Awesome work @hamid13r.bsky.social ! Thank you for taking the time to share your solution more widely :-)

09.10.2025 00:56 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

πŸ™ˆπŸ™ˆπŸ™ˆ

07.10.2025 15:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

finally hit Ο€thon

07.10.2025 15:36 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 2    πŸ“Œ 0
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Check out our new preprint on an integrated pipeline combining in situ #cryo-ET with MALDI #MSImaging for single-cell identification and classification from previously analysed EM-grids.
Link: www.biorxiv.org/content/10.1...

19.09.2025 18:07 β€” πŸ‘ 52    πŸ” 14    πŸ’¬ 1    πŸ“Œ 2
Amyloid reconstructions from cryoSPARC

Amyloid reconstructions from cryoSPARC

Helical Reconstruction of Amyloids in cryoSPARC?
We present guidelines, limitations & future perspectives for processing amyloids in cryoSPARC @structurabio.bsky.social.
Great collaboration of the Kelly Lab and @landerlab.bsky.social #cryoEM #amyloid www.biorxiv.org/content/10.1...

05.10.2025 04:16 β€” πŸ‘ 43    πŸ” 14    πŸ’¬ 3    πŸ“Œ 0

I think for me the most compelling answer for "why fund basic research?" (and the one most relevant to the people doing the work) is that humans are curious and finding stuff out makes us happy and fulfilled. Science is a thing humans like. Life would be more dull and sad if we didn't do it.

end/🧡

03.10.2025 19:32 β€” πŸ‘ 1056    πŸ” 144    πŸ’¬ 34    πŸ“Œ 9

😍

02.10.2025 13:00 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I don’t think they are exactly the same, just sometimes :-) simply saying that many people I admire have personalities people find grating/perceive as arrogant

01.10.2025 15:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

you see lack of professionalism I see desire for authenticity and intellectual honesty

01.10.2025 15:21 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Sad news. Systemic change like this is needed, this a step backwards on the path to a slightly better world

01.10.2025 12:08 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

β€œIf you have a productivity problem, you’re either not annoyed enough, you’re annoyed by something you can’t actually control, or you’re annoyed in the bad way, the kind that makes you want to skip town rather than dig in.” this resonated most for me

30.09.2025 15:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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