Yavuz Yazicioglu

This week in #Science #Immunology: a fantastic paper on #GerminalCenter #BCell #immunometabolism! Check it out!

14.12.2024 15:59 — 👍 25    🔁 5    💬 1    📌 0

Asparagine availability controls germinal center B cell homeostasis Asparagine metabolism is a critical regulator of germinal center B cell function.

This week in #ScienceImmunology: Germinal Center B cells require asparagine (Asn) #metabolism for their function. GC B cells can acquire exogenous Asn from their local environment, but when Asn is limited, they utilise the enzyme asparginine synthetase. @ajclarke.bsky.social @yfy1.bsky.social

14.12.2024 13:28 — 👍 36    🔁 13    💬 2    📌 2

Asparagine availability controls germinal center B cell homeostasis Asparagine metabolism is a critical regulator of germinal center B cell function.

Thrilled to share our latest work on how the non-essential amino acid #asparagine metabolically regulates germinal centers. Huge thanks to my PhD supervisor @ajclarke.bsky.social, colleagues, and collaborators at the @ndorms.bsky.social @ox.ac.uk and @crick.ac.uk

www.science.org/doi/10.1126/...

13.12.2024 21:21 — 👍 10    🔁 8    💬 1    📌 0