Aurelien Dugourd's Avatar

Aurelien Dugourd

@dugourdajf.bsky.social

He/him. Computational Biologist. Lead multi-omic data analysis and integration with mechanistic prior knowledge in complex diseases @saezlab.bsky.social Opinions are my own

235 Followers  |  508 Following  |  18 Posts  |  Joined: 13.11.2023
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Posts by Aurelien Dugourd (@dugourdajf.bsky.social)

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GitHub - adugourd/eve_lp_optimiser Contribute to adugourd/eve_lp_optimiser development by creating an account on GitHub.

A year ago I tried to use LLMs to help me solve a multi-constraint problem in the @eveonline.com game and it wasn't there at all. Today it just balzes through the problem with ease. Such improvements in such a short time is stagggering. See repo if you play that game: github.com/adugourd/eve...

02.12.2025 22:39 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
03.10.2025 10:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Current Vacancies Whether you're a scientist, IT specialist, accountant or administrator, you'll help us tackle the challenges of improving human health & biodiversity in the face of climate change on a global scal...

We are hiring a Postdoctoral Fellow in Computational Biology at EMBL-EBI (Cambridge, UK). Focus: methods to study cell–cell communication from sc/spatial omics data (building on LIANA+ and NicheNet), in collab with @yvansaeys.bsky.social VIB/Ghent.

Details & apply by 13/10/25: tinyurl.com/4shdw8dk

26.09.2025 10:16 β€” πŸ‘ 9    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0
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πŸš€ Une annΓ©e riche de nouveaux espoirs contre le #cancer !

πŸ“½οΈ Retrouvez en vidΓ©o les temps forts qui ont marquΓ© l’annΓ©e 2024 Γ  l’Institut Curie, Γ  l’occasion de la sortie de son rapport annuel.

21.07.2025 09:48 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
In this meme, a young John Connor is talking to the Terminator. 

Wait a second, you re saying you're from the future?

Great question! Thanks so much for asking. Let's think about the answer...hmm! The current year is 1983. Working backwards logically. I'm from the year 1965, which is 300 years in the future. Anything else you'd like to know?

[Blank stare]

I'm sorry, I can see that was not the right answer. I actually came from the year 829392 AD, which is 10 years in the past from this year, which is

In this meme, a young John Connor is talking to the Terminator. Wait a second, you re saying you're from the future? Great question! Thanks so much for asking. Let's think about the answer...hmm! The current year is 1983. Working backwards logically. I'm from the year 1965, which is 300 years in the future. Anything else you'd like to know? [Blank stare] I'm sorry, I can see that was not the right answer. I actually came from the year 829392 AD, which is 10 years in the past from this year, which is

I don't know who made this but 10/10.

17.07.2025 20:11 β€” πŸ‘ 695    πŸ” 157    πŸ’¬ 8    πŸ“Œ 5
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Scientific Database Curator – Fibrosis Transcriptomics We are seeking a technically skilled and biologically literate Scientific Database Curator to join a focused initiative on fibrosis research, hosted at EMBL-EBI in collaboration with the Saez-Rodrigue...

We have a curator position at @ebi.embl.org to work with GSK within a project to understand fibrotic processes (no PhD required). Deadline 20th July.

Please share πŸ™

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

02.07.2025 09:29 β€” πŸ‘ 2    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2
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Postdoctoral Fellow in computational modelling of NeuroImmune Mechanisms of Neurodegeneration (Open Targets) Your role As a Postdoctoral Fellow on the NeuroImmune Open Targets project, you will develop and apply integrative computational pipelines to dissect immune-cell phenotypes and cell–cell interactions ...

Postdoc position in our group at @ebi.embl.org about analyzing single cell data sets to better understand and treat neurodegen diseases, in collab with A Bassett, M Lotfollahi, @bayraktarlab.bsky.social, M Strauss and others within Open Targets. Deadline 20/07.

Please share

tinyurl.com/87wj466m

02.07.2025 09:30 β€” πŸ‘ 5    πŸ” 8    πŸ’¬ 0    πŸ“Œ 1
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Leveraging data as a patient–scientist: frustrations and opportunities - Nature Reviews Nephrology The transition from data scientist to patient–scientist has given me new perspectives into clinical research and strengthened my commitment to open science. Although limitations on data availability h...

I wrote a short piece on how becoming an IgA Nephropathy patient has changed my perspective on biomedical research, developing an appreciation for the challenges in data interpretability & availability and the importance of patient engagement www.nature.com/articles/s41...

23.06.2025 06:19 β€” πŸ‘ 52    πŸ” 17    πŸ’¬ 2    πŸ“Œ 1
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Ever wondered which method to use to infer kinase activities from phosphoproteomics data? πŸ’»πŸ’­Our revised comprehensive evaluation of kinase activity inference tools, done in collaboration with the Zhang lab @bcmhouston.bsky.social, is now out @natcomms.nature.com πŸ”¬ tinyurl.com/4twuc6z4

23.05.2025 07:37 β€” πŸ‘ 47    πŸ” 20    πŸ’¬ 1    πŸ“Œ 2

Was reading this very nice pre-print and I couldn't stop thinking about the parallele with the creation of the Homonculi in Full metal Alchemist Brotherhood xD
arxiv.org/pdf/2505.01441

07.05.2025 15:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Learning tissue representation by identification of persistent local patterns in spatial omics data - Nature Communications Spatial omics reveal tissue structures and can aid patient stratification. The authors present a method to identify patterns in tissue patches, enabling analysis of disease progression and treatment r...

The latest version of the Kasumi manuscript is now published in Nature Comms www.nature.com/articles/s41... Kasumi identifies patterns in tissue patches, enabling analysis of disease progression and treatment response while providing insights into spatial coordination at cell-type or marker level

07.05.2025 13:11 β€” πŸ‘ 26    πŸ” 11    πŸ’¬ 1    πŸ“Œ 1
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PhD/Postdoc in Spatial Omics for Cardiology Post a job in 3min, or find thousands of job offers like this one at jobRxiv!

We have an opening for a PhD/Postdoc in Spatial Omics for Cardiology in Heidelberg πŸ«€ #job #academicjob #phd #postdoc #cadiology πŸ‘‡
jobrxiv.org/job/heidelbe...

22.04.2025 10:28 β€” πŸ‘ 6    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Postdoctoral Position for Cancer Evolution

jobs.dkfz.de/en/jobs/1676... The Odom lab is recruiting postdocs! Please DM if you have questions.

20.04.2025 10:03 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 1

Congrats & Good luck to our @slobentanzer.bsky.social as he starts his group @diabresearch-dzd.bsky.social & @comphealthmunich.bsky.social - he is hiring πŸ‘‡

09.04.2025 07:53 β€” πŸ‘ 13    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0

I like the idea that in Jurassic Park they created Dinosaurs through precision breeding in frogs.

08.04.2025 10:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

This is a very straightforward application of the laws that are in place, and while we still have many more problem in substance with respect to the rise of far right in France, it's already reassuring to see the law being applied to rightfully reduce her influence on our political life. 3/3

01.04.2025 18:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Refusing to admit that her actions constituted an offense is a strong flag that she would relapse if given the opportunity (since she does not consider it to be wrong in the first place). This is a reasonable motivation to declare an immediate execution of the ineligibility. 2/n

01.04.2025 18:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

My understanding regarding the motivation of the judge for the immediate execution of the ineligibility of M. Le Pen: when confronted with proof of her offenses, M. didn't contest the facts, but that they constituted an offense in the first place. 1/n

01.04.2025 18:14 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Congratulations to Peer Bork (EMBL’s Interim Director General), Ewan Birney (EMBL’s Executive Director) & Jo McEntyre (EMBL-EBI’s Interim Director) on their new appointments.

We thank Edith Heard for her leadership at the helm of @embl.org.

www.ebi.ac.uk/about/news/a...

@ewanbirney.bsky.social

31.03.2025 14:28 β€” πŸ‘ 22    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1
31.03.2025 15:10 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Course at EMBL-EBI
From sequences to structures
Protein characterisation using EMBL-EBI APIs
5 June 2025
Virtual

Course at EMBL-EBI From sequences to structures Protein characterisation using EMBL-EBI APIs 5 June 2025 Virtual

Would you like to learn how to use @ebi.embl.org resources for #protein characterisation? This one-day workshop will show you how to retrieve protein sequences, identify homologs, annotate functional domains, and explore structural information using REST APIs: ebi.ac.uk/training/eve...

🧢🧬πŸ–₯️πŸ§ͺ

25.03.2025 09:36 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Interested in doing a sabbatical at EMBL, at one of its 6 sites in Barcelona, Cambridge, Grenoble, Hamburg, Heidelberg or Rome?

Funding call with deadline 15 June, decisions in July.

www.embl.org/about/info/s...

19.03.2025 17:31 β€” πŸ‘ 104    πŸ” 85    πŸ’¬ 1    πŸ“Œ 2
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Postdoctoral fellow - Saez-Rodriguez Group Your group Saez-Rodriguez Research Group Your supervisor Julio Saez-Rodriguez Your role As a postdoctoral fellow in the Saez Rodriguez group, you will develop and apply computational methods and tools...

6 days left to apply to the Post-doc opening in our lab
@ebi.embl.org to develop&apply #bioinformatics & #machine-learning methods to study intra-/extra cellular networks to extract disease mechanisms from #single-cell and #spatial multiomic data: embl.wd103.myworkdayjobs.com/EMBL/job/Hin...

17.03.2025 18:01 β€” πŸ‘ 31    πŸ” 27    πŸ’¬ 1    πŸ“Œ 2

Congrats to our @juliosaezrod.bsky.social and all other elected fellows of the International Society for Computational Biology (ISCB) as part of the 2025 Class

17.03.2025 18:03 β€” πŸ‘ 23    πŸ” 6    πŸ’¬ 2    πŸ“Œ 2
A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient

In @elife.bsky.social: A comparative analysis of planarian regeneration specificity reveals tissue polarity contributions of the axial cWnt signalling gradient doi.org/10.7554/eLif...

13.03.2025 23:50 β€” πŸ‘ 21    πŸ” 7    πŸ’¬ 4    πŸ“Œ 0
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Changes in EMBL-EBI leadership Jo McEntyre will become Interim Director of EMBL-EBI as Ewan Birney takes up the role of EMBL Executive Director.

πŸ“£ EMBL-EBI leadership update

Jo McEntyre will step into the role of Interim Director of EMBL-EBI, as Ewan Birney transitions to a new position as Executive Director of EMBL following Edith Heard’s upcoming departure.

www.ebi.ac.uk/about/news/a...

13.03.2025 13:02 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1
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Postdoc - Statistics and machine learning with spatial omics and single-cell perturbation data – Huber Group @ EMBL Precision Oncology and Multiomics

Postdoc - Statistics and machine learning with spatial omics and single-cell perturbation data
www.huber.embl.de/group/posts/...

12.03.2025 13:08 β€” πŸ‘ 30    πŸ” 15    πŸ’¬ 0    πŸ“Œ 2
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Digital sovereignty – Huber Group @ EMBL The US is now a mafia-style extortionist you want to stay away from

It's time for individuals and organizations in Europe and other democratic countries to move mission- or life-critical IT services and infrastructure outside the reach of the US government; noting that US tech companies have already largely subordinated themselves.

www.huber.embl.de/group/posts/...

08.03.2025 09:15 β€” πŸ‘ 78    πŸ” 32    πŸ’¬ 4    πŸ“Œ 2