Reproductive BioMedicine Online

The results from this analysis into prevalence and impact of PCOS in China, show infertility attributable to PCOS as increasing as a faster rate than the global burden of the disease; making PCOS a major public health problem and a public health priority that needs attention

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This new review calls for an interdisciplinary approach involving gynecologists, reproductive endocrinologists, and fertility specialists to navigate the complexities of fertility preservation in endometriosis.

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our LinkedIn version here, which you can subscribe to separately:

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☕ Settle in to your Sunday morning with a nice big coffee and catch up with the latest journal highlights and new perspectives on recent papers in the October edition of RBMO Insights.

Read it from our email version here: sh1.sendinblue.com/ais0e855z9pf...

.....or if you prefer............👇

This study investigates the effect of a web-based, multi-component decision aid on key elements of informed decision-making among couples at risk of transmitting a genetic disease to their offspring in a multi-centre randomized controlled trial.

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The study demonstrates the ability of AI tool ERICA (Embryo Ranking Intelligent Classification Algorithm) to enhance the reliability of embryo selection; increasing accuracy, and reducing subjectivity and bias.

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#RBMOeditorsChoice #ClinicalEmbryology #AIinIVF

AI simulation training can play a valuable role in embryology, similar to fields like surgery. By recreating repeatable real-life scenarios, simulations enhance skill development, providing controlled environments to practice and improve techniques.

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#RBMOeditorsChoice #AIinIVF

Selected as an Editor’s Choice article from our October issue, this article adds some valuable insights into the potential for predictive AI tools to influence the decision-making process of clinical embryologists.
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#RBMOeditorsChoice #ClinicalEmbryology #AIinIVF

This new Countercurrent Contribution from Paul Pirtea and Baris Ata challenges the commonly used 7mm threshold for endometrial thickness in ART, arguing that it should complement a comprehensive assessment and plan of personalized, data-driven care, not rigid thresholds.

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This study describes Swedish 'single mothers by choice' receiving funded treatments, comparing background, treatment motives, experiences of the psychosocial evaluation, support needs, reflections on motherhood (including during COVID-19), and post-birth circumstances.

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Georges Raad and colleagues highlight the diagnostic value of sperm characteristics in predicting embryological outcomes.

Post-preparation sperm vacuolization shows significant prediction of fertilization, and mitochondrial activity in raw semen predicts blastulation rates

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This study shows a correlation between TMSC values and clinical live birth rate (CLBR) when considering the total number of oocytes used, supporting the notion that sperm quality is a key factor in achieving pregnancy, in conjunction with female factors.

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🔥 New RBMO Hot Topic selection!

Subtle reciprocal translocations are not uncommon and as shown in this analysis, have no impact on pregnancy rates: does this shed light on the detection and interpretation of relatively minor abnormalities in PGTA?’

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#RBMOHotTopic

The October edition of Insights is out!

We have a fantastic issue for you, with a report from the Cambridge University Bob Edwards event, the recording of our recent Journal Masterclass webinar, three Talking Points, article highlights, and more!

sh1.sendinblue.com/ais0e855z9pf...

#RBMOinsights

Two media appearances from RBMO Editor Richard Anderson this week

On the BBC news, and quoted in this @theguardian.com article, commenting on the recent breakthrough in transforming skin cells into human eggs (reported in Nature Communications)

www.theguardian.com/science/2025...

With a change from multi- to single step protocols, shortening vitrification as well as warming time of blastocysts, laboratory techniques were made simpler while maintaining high blastocysts survival rates and high pregnancy outcomes.

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The authors say this model will help improve operations and outcomes in response to the profession’s dynamic environment and various evolving demands.

Read the full Review for free from issue 51.3 now:

doi.org/10.1016/j.rb...

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The framework by authors Jordon Swain, Russell Lemler, and Jason Swain addresses the leadership needs of the field, considering the development and demands of roles including MDs, Office Managers, C-Suite personnel, and all who hold traditional, formal leadership roles in the IVF industry.

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A new Review article from our September issue presents that Leader Development Model - an evidenced-based training framework of five distinct elements: individual readiness, developmental experiences, new knowledge, reflection, and time.

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This new systematic review investigates whether gonadotrophin-releasing hormone agonist pretreatment has a positive effect on pregnancy outcomes in women with adenomyosis who were undergoing a frozen embryo transfer cycle.

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#ClinicalAssistedReproductiveTechnology

Issue 51.4 of RBMO is out now, with 16 Research Articles, 3 Commentaries and a Review, across seven of our specialist sections!

www.rbmojournal.com/issue/S14726...

As we celebrate the centenary of his birth, this Commentary article from Kamal Ahuja describes Bob Edwards as a polymath, and reflects on the profound breadth of creative influences and relationships which characterised his lifetime of achievements.

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Today marks the centenary of the birth of Sir Robert Edwards.

In this special article in our newsletter we reflect on the legacy of the man - the polymath - responsible for the world’s first IVF baby in 1978, and our journal, Reproductive Biomedicine Online.

bit.ly/RGEcentenary

In an article published recently in RBMO Dr Ahuja makes a case for Bob Edwards as a polymath: 'a scientist whose work and creativity spread beyond the learning of a single discipline and into a labyrinth of connected human interests'

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#RobertEdwardsCentenary #IVF

Dr Kamal Ahuja presenting his talk 'Robert Edwards: the polymath father of IVF'.

Dr Ahuja first met Sir Edwards as a PhD student in the Marshall Laboratory in the 1970s, with a closely collaborative career which included the co-founding of our journal, RBMOnline, in 2000.

#RobertEdwardsCentenary

Mike MacNamee presenting the Bob Edwards plaque outside of the Physiology Building

#RobertEdwardsCentenary #IVF

In the opening session we have enjoyed hearing from Kay Elder (pictured), Marta Shahbazi, Julie Tang, Geraldine Jowett, and Ana Orsi with talks on the science behind the techniques, and their application in clinical practice.

#RobertEdwardsCentenary #IVF

We are at the Physiology Lecture Theatre, at University of Cambridge for an afternoon of lectures honouring the life, work and legacy of Sir Robert Edwards, whose work revolutionised fertility treatment through the invention of in vitro fertilisation.

#RobertEdwardsCentenary #IVF

A new Commentary article from Mitchel Schiewe , marks a waypoint along our progress from “fast to fastest” approaches in the vitrification and post-warming rehydration of human blastocyst

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#RBMOCommentary #ClinicalEmbryology

This new research article from Andrew Drakeley and colleagues presents an approach for predicting male-factor miscarriage risk by utilising the Extend® neutral comet assay.

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