Old mitochondria regulate niche renewal via α-ketoglutarate metabolism in stem cells - Nature Metabolism
Andersson et al. show that intestinal stem cells enriched for old mitochondria are metabolically distinct and have enhanced ability to regenerate the epithelial niche.
Proudly presenting Simon’s @simonsterson.bsky.social paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism
@naturemetabolism.bsky.social www.nature.com/articles/s42... @helsinki.fi @metastem.bsky.social 🧵1/8
14.07.2025 10:20 — 👍 67 🔁 22 💬 4 📌 3
Congratulations Matteo 🎉
04.04.2025 19:35 — 👍 1 🔁 0 💬 0 📌 0
HHMI Hanna Gray Fellow @StanfordMed
Aging and cancer stem cell heterogeneity - ICREA research professor - Quantitative Stem Cell Dynamics lab
at IRB Barcelona 🇦🇷🇪🇺🇺🇸 fraticellilab.com
Computational biologist interested in cancer evolution, maths modelling and Bayesian stats.
Haematologist & Scientist @petermaccc.bsky.social and University of Melbourne - Group Leader @thedawsonlab.bsky.social - views expressed are my own
PhD student @ Adameyko Lab / http://adameykolab.eu / twitter: @sv_isaev / https://isaev.cc
The Zelzer lab performs interdisciplinary research on the development and morphogenesis of the musculoskeletal and proprioceptive system 🐁🔬🦴🧬
Nature Aging is a thematic journal from the Nature Portfolio that serves the broad aging research community. Follows & posts ≠ endorsements.
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Nature Metabolism publishes studies that advance our understanding of metabolic and homeostatic processes in physiology and disease.
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Group Leader @ BIH Berlin and MPI Molecular Genetics. I play around with DNA because I‘d like to know how the genome functions.
Research group leader @German Cancer Research Center, reconstructing human development and disease using cell fate engineering
Our group develops and applies computational approaches to study molecular variations and their phenotypic consequence. We are part of DKFZ and EMBL.
Website: https://steglelab.org/
Scientist at DKFZ and EMBL in Heidelberg, loving stats, genomics and genetics. @OliverStegle@genomic.social. For group news see @steglelab.bluesky.social
Senior Investigator @ Altius Institute for Biomedical Sciences. Research: High-resolution mapping of chromatin structure & function. Fun: Mountain shenanigans and skiing turns all year. Seattle, USA/Patagonia Chilena (🇺🇸🇨🇱). http://vierstra.org
Group leader @crg.eu | blood, single cell, synthetic genomics
Gene regulatory networks and genome evolution. How do single cells make up their minds?
@NimwegenLab@mstdn.science
@NimwegenLab on twitter. Sorry X.
Lab of Pekka Katajisto @pekka-katajisto.bsky.social at University of Helsinki and Karolinska Institutet. We study stem cells, aging, metabolism, organelle age and niche interactions https://www.katajisto-lab.com
