Vincent de Boer's Avatar

Vincent de Boer

@vcjdeboer.bsky.social

physiology | metabolic fluxes | mitochondria | health | metabolism in model systems | metabolic communication | epigenetics | open science | @WUR

67 Followers  |  169 Following  |  2 Posts  |  Joined: 13.11.2024
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Posts by Vincent de Boer (@vcjdeboer.bsky.social)

Yibo Qiu, Zan Huang, Zhiyu Wang, Handi Liu, Yiling Qiao, Yifeng Hu, Shu'ang Sun, Hangke Peng, Ronald X Xu, Mingzhai Sun
BioMARS: A Multi-Agent Robotic System for Autonomous Biological Experiments
https://arxiv.org/abs/2507.01485

03.07.2025 05:49 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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The role of protein lactylation: A kaleidoscopic post-translational modification in cancer Lysine lactylation affects histone and non-histone proteins, influencing gene expression and protein function. Increasing studies in this field are revealing the lactyl-moiety sources, alongside its m...

The role of protein lactylation: A kaleidoscopic post-translational modification in cancer: Molecular Cell www.cell.com/molecular-ce...

13.03.2025 13:55 β€” πŸ‘ 18    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age Mitochondrial respiration atlas reveals functional signatures of aging across diverse tissues and organ systems.

Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age

doi.org/10.7554/eLif...

21.12.2024 19:33 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner The combined activities of Cpt1 and Cpt2 facilitate mitochondrial fatty acid oxidation. Choi etΒ al. describe distinct phenotypes induced by Cpt1 and Cpt2 deficiencies and the uptake and oxidation of extracellular long-chain acylcarnitines. These findings show non-cell-autonomous intercellular acylcarnitine metabolism.

Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner: Cell Reports

www.cell.com/cell-reports...

14.12.2024 13:44 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Gotta extract some PBMCs?
Or run a Seahorse cell metabolic analysis?

@vcjdeboer.bsky.social lab’s Portfolio is a goldmine of protocols πŸ”₯

Based at πŸ‡³πŸ‡± Wageningen University, they study the inner workings of mitochondria and how mitochondrial metabolites communicate with epigenetic machinery.

11.12.2024 08:21 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0