Marcin Czerwinski

Another great paper from @pawelburkhardt.bsky.social about the subepithelial nerve net (SNN) in ctenophores: it forms synaptic connections with effector cells (some 17 cell types). The signal processing within the aboral organ relies on synaptic and nonsynaptic communication.

tinyurl.com/2j5ud64m

Under certain stress conditions, bacteria accumulate polyphosphate (polyP), which interacts with a long variant of CobB deacetylase, triggering a regulatory coupling to prevent DNA replication initiation
tinyurl.com/2cu8cnx8

Even more excited — our paper is featured on the cover of Science Advances!

Huge thanks to @alexandrejan.bsky.social who took this incredible photo of a ctenophore (aka comb jelly) and the editors.

Here’s the cover 👇

www.science.org/doi/10.1126/...

Another great article by @mastroianni.bsky.social on the current #SciencePublishing system.

Don't publish with for-profit publishers like Elsevier, Springer Nature, et al. It's really simple. There are so many cool #PlantScience society journals. #SciPub

See also: bsky.app/profile/soms...

FED-2, I had one of these! Here is a pic taken by my dad in 1987. Niedzica, Poland.

Wee thread 🧵⬇️ on our new #glycotime with @siglecdude.bsky.social John Klassen and @glycocode.bsky.social 🥳 where we show Siglecs as molecular precision tools, able to recognise sialylated glycans with surgical precision in their natural environment, not bad for a lectin! 😎

doi.org/10.1038/s420...

B4GALNT3, an enzyme that synthesizes GalNAcβ1-4GlcNAc, contains a unique non-catalytic PA14 domain, which is a lectin domain recognizing sulfated glycans (eg. Gal[6S]β1-4GlcNAc[6S]). Such sulfated glycans negatively regulate the PA14-dependent catalytic activity.
tinyurl.com/3zymxxdh
#glycotime

Fucosylation inhibits pertussis toxin binding to the cell surface, while sialylation and N-linked glycosylation promote the binding, resulting in increased intracellular ERK phosphorylation
tinyurl.com/bdza4j38

#glycotime

Alpha-Gal syndrome ⤵️🟡 sad #glycotime 😞

All you ever wanted to know about clinical gene therapy for hemophilia and globin disorders: in vivo and ex vivo methods, lentiviral and adeno-associated viral (AAV) vectors, and gene silencing by the CRISPR-Cas9 gene editing system.
@rkaczmarekdr.bsky.social

tinyurl.com/3yctsr5a

#hemophilia

A photo of a large red comb jelly on a black background.

Calling all #ctenophore researchers and artists!
Joe Ryan is organizing the Ctenopalooza Ctwo meeting, which we will host at MBARI in California August 23-25. 🦑🧪🌊
www.mbari.org/event/ctenop...
Come swap notes with fellow enthusiasts about the latest news in comb jellies.

Thank you, Anne! No, but I plan to write a piece. It is puzzling why E. granulosus has chosen Gal alpha1-4 Gal to cover its mucins, despite some humans (of P2 blood group) produce them in small amounts.

Jaki związek mogą mieć antygeny układu grupowego krwi P1PK z bąblowicą? Moje uwagi na blogu eksperymentmyslowy.pl

tinyurl.com/24h5nh5k

Exciting work! All diabetic individuals should travel to Tibet or the Andes🏔️

Tak pisał w "Głosie Pana" (1968 r.)

Ten Dobrowolny Upowszechniacz przerabiał Indiotów na lśniące krążki, z których potem czarne automaty układały piękne wzory. W zasadzie to też pasuje, bo w końcu wszyscy wyglądali tak samo.

Tylko Podróż 13 przychodzi mi di głowy. Na planecie o nazwie Panta wszyscy mieli takie same twarze. Dzięki temu jednostki w zasadzie przestały istnieć.

Jako "twarde" SF, zdecydowanie tak. Jak dzieło literackie, preferuję Cyberiadę, choćby ze względów językowych.

Tak, to prawda. Z kątów stacji Solaris wyłażą najgorsze upiory utkane z naszych myśli. Bardzo Lemowskie podejście.

Moje uwagi na temat "Solaris" Stanisława Lema: dlaczego ta książka jest ciągle aktualna?

tinyurl.com/5dk5786v

Jeszcze tylko dwa tygodnie, potem do remontu. Mają być mijanki w Jełowie i Tułach.

Rail line Opole-Kluczbork with the rail bus SA103 approaching Kały station.

📷Canon EOS 5
🔘70-300 mm
🎞️Ilford FP4+

#BelieveInFilm

Now this is big: under freezing conditions, a small polymerase ribozyme called Q45 can synthesize itself and its complementary strand. It seems that life might have started in the cold: Earth’s natural freeze-thaw cycles may have helped concentrate life’s building blocks.
tinyurl.com/36tnesn5

"Ynk usiadł na śniegu, na swoim chudym ogonie, a jego pysk sfałdował się od trosk"

Wrocław, Kępa Mieszczańska.

📷Minolta X-300
🔘28 mm
🎞️Ilford Delta 100

#BelieveInFilm
#Turpism

Elon Musk posted about race almost every day in January Many social media posts by Tesla CEO on his platform are indiscernible from those of white supremacists, say experts

“The richest man in the world posted about how the white race was under threat, made allusions to race science or promoted anti-immigrant conspiracy content on 26 out of 31 days in January”

www.theguardian.com/technology/2...

Leveraging mirror-image glycans in carbohydrate materials Chirality has become a fundamental design principle to craft peptide materials. In contrast, the systematic exploitation of chirality to build glycan materials remains largely unexplored, despite the…

🔓Don't miss this #OpenAccess review from Dominik Weh & @delbiancom.bsky.social at @mpici.bsky.social in our latest issue looking at how mirror-image glycans can be leveraged to tailor carbohydrate materials

Check it out in full on our website🔽

Murów, opolskie voivodeship. Abandoned rail station.

📷Canon EOS 5
🔘70-300 mm
🎞️Ilford XP2

#BelieveInFilm
#Turpism

Finally, a detailed review about C-mannosylation: mechanism of C-mannosyltransferases and the influence of the C-mannosylation on the function of several proteins. Highly recommended to everyone in this type of post-translational modification!
tinyurl.com/3ywjmfk3

#glycotime