Naina Gour

#newPI feels

The fun leaving your body the moment you're done with the science and it's time to get it published

Architecture of the neutrophil compartment - Nature Mapping of the neutrophil compartment using single-cell transcriptional data from multiple physiological and patological states reveals its organizational architecture and how cell state dynamics and trajectories vary during health, inflammation and cancer.

Nature research paper: Architecture of the neutrophil compartment

go.nature.com/3KzY1CV

Our cool new paper depicting fibroblasts more than a scaffold during airway allergy. #Il33 #ILC2 #complement

Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy @cp-cellreports.bsky.social @atakkatan.bsky.social @hopkinsmedicine.bsky.social
www.cell.com/cell-reports...

How a mattress sensor and smartwatch confirmation led to a patient's diagnosis of complete heart block and need for a pacemaker @nejm.org www.nejm.org/doi/full/10....

Proteoglycofili are glycosaminoglycan-containing fibrillar components released by neutrophils to neutralize bacteria Alternative to the formation of NETs, André et al. describe here that viable neutrophils may release a fibrillar component named proteoglycofili or PGF upon stimulation. PGF formation is associated wi...

Thrilled to share that neutrophils produce extra long fibrillar components named proteoglycofili or PGF. PGF are released by living neutrophils and do not contain DNA. They might look like NETs but are not NETs…

www.cell.com/cell-reports...

GPR43 in eosinophils suppresses the emergence of pathogenic Siglec-F high neutrophils in allergic airway inflammation in mice @natcomms.nature.com
www.nature.com/articles/s41...

A bacterial toxin disarms gut defenses against inflammation Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice

New discovery in ulcerative colitis: a bacterial toxin that kills macrophages and increases inflammation, which could be the foundation for a new treatment
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org