Martín Estermann

A 5-day old chicken embryo above a yolk. The vasculature and yolk remain in tact.

It is so cool to be able to see things like this (#DevBio) in real life and share it with students. 🤩

🚨LatinxDB organize: “Why didn’t I know this before? What to expect from a PhD or a postdoc in life sciences”

Thanks Estefania Vasquez, M. Fernanda Palominos and Emma Rangel for creating this space and discussion. @niasv.bsky.social @fishfena.bsky.social

Join us at 2025NDiSTEM @sacnas.bsky.social

Poster of Development presents... webinar on Wednesday 15 October at 09:00 BST (UTC+1). Chair: Alex Eve. Details of 2 speakers and talks: Osvaldo Contreras from the Victor Chang Cardiac Research Institute, talk titled 'OpenEMMU: A low-cost EdU multiplexing methodology for studying DNA replication and cell cycle dynamics’; then Yinan Wan from Biozentrum University of Basel, talk titled ‘Whole-embryo spatial transcriptomics: from fate to form’.

Our next #DevPres webinar focusses on development across scales with talks from Osvaldo Contreras @osvaldoics.bsky.social & Yinan Wan, chaired by Alex Eve @amjeve.bsky.social

📅 15 October, 09:00 BST (UTC+1)

Register here: us02web.zoom.us/webinar/regi...

Our latest ‘call for preLighters’ closes tonight!

Interested, but didn’t find the time to write an application? Expressions of interest are also welcome – just email us at prelights@biologists.com

Why join? See what other preLighters have to say…⬇️👀

📢To all the sex determination lovers! 📢

Get ready for the 10th International Symposium on the Biology of Vertabrate Sex Determination (VSD).

We exchange the nostalgic Hawaii beaches with the gorgeous Crete beaches 🏖!
The meeting will take place on 23-27 March 2026.

biology-of-vsd.my.canva.site

🚨 New call for preLighters!🚨

Help us highlight the most exciting biological #preprints. Share your insights, build your profile, and be part of a supportive community! 🌍

Interested? Apply today & help shape the future of science publishing! 📢

More info: prelights.biologists.com/news/join-th...

✨If Monet studied mouse ovaries 🎨 Stromal cells 💜 Follicular cells 🔵 and Fatty Cells 🟡. Together, they reveal the cellular architecture and functional zones of the ovary 🔬 Image provided by @shmimberly.bsky.social 🧪 #FluorescenceFriday #ReproductiveBiology

Flores-Flores in 2025 Class of Pew Latin American Fellows Pursuing Scientific Advances Pediatrics Postdoctoral Fellow Marycruz Flores-Flores, PhD, is one of 10 in the 2025 class of the Pew Latin American Fellows Program in the Biomedical Sciences announced today by The Pew Charitable Trusts.

🎉 Big news! 10 postdoc fellows from 5 Latin American countries have joined the 2025 class of #PewLatinAmericanFellows, and we’re proud to share that one is our own @mary-flores.bsky.social! Learn more: bit.ly/45rgN5L @cumedicalschool.bsky.social @cuanschutz.bsky.social @chrmosimann.bsky.social

✨Development meets design in this embryonic chameleon lung 🫁 🦎. Smooth muscle swirls 🟣 and branching tips and cartilage 🟢 come together in reptilian lung morphogenesis. Image taken by @drkatiegoodwin.bsky.social 🔬🧪
#FluorescenceFriday #DevBio

From Shosei Yoshida's beautiful talk @ssrepro.bsky.social. Differentiation waves in mouse seminiferous tubules (Stra-8 eGFP). Absolutely spectacular👏 #ReproRocks #ComplexSystems #Microscopy

✨Unexpected but beautiful! 🔬
4 hpf zebrafish embryos injected with BFP 🔵, GFP,🟢 and RFP🔴 mRNAs (1:1:1) showed mosaic, multicolor expression, resembling a brainbow without any genetic recombination 🧬🌈 image taken by A.J. Treichel 
#FluorescenceFriday #Zebrafish #DevBio

Lovely work by @martinestermann.bsky.social and colleagues from the Capel lab! Together with our recent work (www.biorxiv.org/content/10.1...), this really makes a strong case that lactate is crucial to supporting male germ cells in vivo - from flies to mammals.

🚨 New preprint alert! 🚨
Excited to share the preprint that marks the beginning of my journey into the world of metabolism! 🍭🧬
A new chapter exploring how metabolic pathways shape gonadal development.
There’s more to come, stay tuned!
#DevelopmentalBiology #Metabolism

🐌💫 Snail embryos never looked so fabulous!
Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball.
Image from Clemens Cabernard & Adam von Barnau Sythoff 🪩🧬 #FluorescenceFriday

🐣✨ TUJ1 staining reveals the forming trigeminal ganglion in a chick embryo! Image taken by Rocio Márquez from @pstrobl.bsky.social lab, where they investigate how neural crest and placode cells communicate during the formation of this sensory structure 🔬🧪
#FluorescenceFriday

LASDB board meeting during the @socdevbio.bsky.social / @isdb.bsky.social / LASDB joint meeting in San Juan, PR 🌴✨! We’re excited for what’s ahead for developmental biology and the growing role of Latinx scientists in the field. 💪🏽🧬 🐸🐟🐣🐭🪰 #DevBio #LatinxInScience #LASDB #LatinxDB

My first light sheet scanning with a #zebrafish 🩷 embryo! #devBio
#microscopy🎉

4/
🎉 Proud to share this work with co-first author Paula Brown and the Yao lab.
Big thanks to the Mouse Model Core for making this possible! Use it. Share it. Build with it.
🧬 #DevBio #ReproSci

3/
Our model shows:
✅ High specificity for interstitial cells
✅ Activity in embryonic and adult reproductive tissues
✅ No recombination in Sertoli, granulosa, or germ cells
✅ Can also label Nr2f2+ lineages in other organs (lung, kidney)

2/
Most Cre lines used in gonadal research focus on supporting or germ cells.
The interstitium? Often neglected, despite its essential roles in steroidogenesis, structural support, and signaling.
We wanted to fix that. 🧬

🧵1/
🚨 New tool for reproductive biology!
We generated a Nr2f2-iCreERT2 mouse—an inducible Cre model that specifically targets interstitial cells in both male and female gonads.
Read more in our new @biolreprod paper:
🔗 doi.org/10.1093/biol...

🧠✨ E14 mouse embryo lighting up with neural progenitors!
Nestin (⚪️), p73 (🟢), and Tbr2 (🔴) mark distinct progenitor populations shaping the nervous system.
Vishal Lolam is investigating how their balance is disrupted in neurodevelopmental disorders.
#FluorescenceFriday

One of my favourite IF images is participating for the #SSR 2nd Annual #ReproBioArt Image Contest!
Mind helping with a vote?

⬇️

woobox.com/2poyka/galle...

Sugar is usually thought of as a cellular fuel, but it also changes how cells differentiate. preLighter (@prelights.bsky.social) @martinestermann.bsky.social shows that metabolites, such as sugars, influence the development of sex organs—ovaries & testes. Sweet story!

#2025SDB #2025SDB #ICDB2025

🎆🧬 Fireworks in the making!
At 3 days, Nematostella vectensis is already producing stinging cells across its body. These genes (🩷💛💙) cluster in the tentacle tips and across the sea anemone juvenile body 🪼✨ image provided by @gelatinoussting.bsky.social #FluorescenceFriday #DevBio

✨#FluorescenceFriday brings you a glowing Berghia stephanieae juvenile! This stunning sea slug is lit up with Anti-α-Tubulin 🟢, revealing the dense network of cilia that help it glide across surfaces. 🐌💫 Image taken by @Luiza-O-Saad.bsky.social
#Microscopy #DevBio

This is figure 1, which shows iron-metabolism pathways are uniquely activated in embryonic gonads during male sex determination.

Iron deficiency in pregnant mice may lead to the development of ovaries in a small proportion of offspring carrying XY chromosomes, which typically determine male sex, according to a study in Nature. go.nature.com/45FjiTK 🧪

Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: forms.gle/gf7Lid9fXcmb... 🧪

🦋✨ #FluorescenceFriday meets developmental biology!
This glowing "butterfly" isn't an insect, it's a transverse section of a developing chicken gonad. When art meets science, even sex differentiation takes flight! Image taken by @martinestermann.bsky.social #ChickenModel #DevBio 🐥🔬