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Waser Group

@lcsolab.bsky.social

Organic Chemistry Lab at ISIC EPFL, NCCR Catalysis, SNE ChemBio https://www.epfl.ch/labs/lcso/ https://www.linkedin.com/in/lcso-lab/ Starter packs - OrgChem https://go.bsky.app/NSEFPFJ https://go.bsky.app/GwH8t - Chem. in CH https://go.bsky.app/CdvVFKj

1,290 Followers  |  1,325 Following  |  157 Posts  |  Joined: 23.11.2024  |  1.8828

Latest posts by lcsolab.bsky.social on Bluesky

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lol @ PhD's in my pocket - still can't electron push ๐Ÿคทโ€โ™‚๏ธ

08.08.2025 15:59 โ€” ๐Ÿ‘ 21    ๐Ÿ” 3    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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๐Ÿšจ Looking for a new research opportunity?๐Ÿšจ | Louise Walport ๐Ÿšจ Looking for a new research opportunity?๐Ÿšจ We are looking to recruit two talented postdocs to join our group based at the Molecular Science Research Hub at Imperial College London: - Both to join ou...

Are you excited about using cyclic #peptides in #DrugDiscovery?

Here is a great opportunity to perform a #postdoc with a great mentor in the group of @ljwalport.bsky.social at @imperialcollegeldn.bsky.social!

www.linkedin.com/posts/louise...

#ChemBio #Chemistry #ChemSky

10.08.2025 07:59 โ€” ๐Ÿ‘ 5    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Halogen Bonding in Solution: Under Pressure The first study of the high-pressure behavior of organic halogen bond donors in solution is presented: HP-NMR titrations were performed in various solvents, primarily with a neutral tridentate halogen...

A paper with a Queen song title? Check! (Even though that was an easy one).
We've investigated the high pressure behavior of halogen bonding and found some unexpected solvent @solvationsci.bsky.social dependence:
pubs.acs.org/doi/10.1021/...

07.08.2025 10:36 โ€” ๐Ÿ‘ 12    ๐Ÿ” 4    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0
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New #LCSOSynthesisProblem! | LCSO Lab New #LCSOSynthesisProblem! This week, Carlo challenged us to the total synthesis of Asnovolin E and related spiromeroterpenoids by Prof. John Porco and co-workers. ๐Ÿ’ก Want to challenge yourself or you...

Next edition of #LCSOSynthesisProblem
www.linkedin.com/feed/update/...

07.08.2025 13:18 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Congrats to Elliott, @hls111.bsky.social, Olivera, Patrick, Alexander and Daniel! Ligand Design Enables the Palladium-Catalyzed Intermolecular Carbochlorocarbonylation of Alkynes and Cyclopentenone Formation @jacs.acspublications.org pubs.acs.org/doi/full/10....

06.08.2025 20:51 โ€” ๐Ÿ‘ 13    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Summer update of the research website @lcsolab.bsky.social with improved introduction, addition of the latest progress and a new page dedicated to collaborative works!

www.epfl.ch/labs/lcso/re...

06.08.2025 16:04 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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In our new paper in JACS Au, with the Sagara group from the Institute of Science Tokyo, we introduce flippers than respond to stretching rather than compression and applicability to the materials rather than the life sciences (GOA).

pubs.acs.org/doi/10.1021/...

06.08.2025 06:10 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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#LCSOJournalClub 197.1 (highlighted in picture): a preprint at ChemRxiv of Mahiuddin Baidya and co-workers from IIT Madras on the NHC-catalyzed three-component coupling of aldehydes, styrenes andโ€ฆ | L... #LCSOJournalClub 197.1 (highlighted in picture): a preprint at ChemRxiv of Mahiuddin Baidya and co-workers from IIT Madras on the NHC-catalyzed three-component coupling of aldehydes, styrenes and lamb...

Edition 197 of #LCSOJournalClub
www.linkedin.com/feed/update/...

05.08.2025 13:23 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Mechanistic Study of the Light-Initiated Generation of Free Diazoalkanes: Towards Photo-Orthogonal Synthesis
Please see the prospects for photo-orthogonal synthesis by increasing the conc. in the photostationary state and the lifetime of nonstabilized diazo compounds for stepwise reactions #ChemSky

05.08.2025 10:49 โ€” ๐Ÿ‘ 7    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Gold-Catalyzed Umpolung Sonogashira-Type Coupling of Boronic Acids with Alkynyl Iodine(III) Reagents A gold-catalyzed C(sp)โ€“C(sp2) cross-coupling reaction between hypervalent iodine(III) reagents and boronic acids has been developed, enabling the efficient synthesis of alkyne derivatives. This method...

Gold-Catalyzed Umpolung Sonogashira-Type Coupling of Boronic Acids with EBx reagents published by Jinhua Yang and co-workers in @orgbiomolchem.rsc.org

doi.org/10.1039/D5OB...

05.08.2025 06:05 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Rethinking the Excited-State Redox Properties of Iron(III) Complexes for LMCT Photoredox Catalysis The reduction potentials of electronically excited states are crucial input values for photoredox reaction design. Since they are not directly measurable, they are typically estimated from the corresp...

Rethinking Iron Photoredox Catalysis

For Fe(III) complexes, excited-state redox potentials donโ€™t follow the usual rules - standard estimation methods fall short

Joรซl Wellauer with Paul Francis & colleagues at Deakin University in @jacs.acspublications.org

pubs.acs.org/doi/10.1021/...

04.08.2025 13:48 โ€” ๐Ÿ‘ 16    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Please meet Andreu Tortajada Navarro @antorna.bsky.social @unifrChemistry, member of @helvchimacta.bsky.social #earlycareer international advisory board. This is our 12th #authorprofile, enjoy reading about Andreu. doi.org/10.1002/hlca...

04.08.2025 08:29 โ€” ๐Ÿ‘ 9    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Home | Research Group Schmid | University of Basel

๐Ÿ’ฅ We have 3 positions open in my lab in Basel, Switzerland๐Ÿ‡จ๐Ÿ‡ญ:
#nanopores #smFRET #biomolecular #dynamics #singleMolecules

Weโ€™re looking for talented & ambitious new colleagues enthusiastic about biomolecular dynamics & single-molecule tech.

Please share broadly, thank you!๐Ÿค

schmid.chemie.unibas.ch

31.07.2025 14:34 โ€” ๐Ÿ‘ 32    ๐Ÿ” 29    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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Structural Control of Metal-Centered Excited States in Cobalt(III) Complexes via Bite Angle and ฯ€โ€“ฯ€ Interactions CoIII complexes have recently become an important focus in photophysics and photoredox catalysis due to metal-centered excited states with strong oxidizing properties. Optimizing chelate ligand bite a...

Bite angle optimization weakens ligand fields in cobalt(III) complexes, yet lifetimes can increase due to rigidification

pi-donor (instead of pi-acceptor) ligand properties are key

now in @jacs.acspublications.org

pubs.acs.org/doi/10.1021/...

31.07.2025 07:35 โ€” ๐Ÿ‘ 17    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Late-Stage Cโ€“H Diversifications with Ambiphilic ฮฑ-Bromoboronates: Versatile Access to Transformable meta-Boroalkyl Scaffolds The ruthenium-catalyzed meta-Cโ€“H alkylation is an increasingly powerful strategy in the arena of remote Cโ€“H activation. Currently, the synthesis utility of this strategy is compromised owing to its re...

๐Ÿš€ Fresh off the press in ACS Catalysis!
Check out our efficient and modular approach with Ru-catalyzed meta-Cโ€“H functionalization using readily available ฮฑ-bromoboronates, achieved under exceedingly mild conditions with high chemo- and site-selectivity. ๐Ÿ‘

pubs.acs.org/doi/10.1021/...

30.07.2025 07:31 โ€” ๐Ÿ‘ 8    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Pushing the Thermodynamic and Kinetic Limits of Near-Infrared Emissive CrIII Complexes in Photocatalysis Photoactive CrIII complexes are typically based on polypyridine coordination environments, exhibit red luminescence, and are good photo-oxidants but have modest photoreducing properties. We report new...

Cr(III) complexes with enhanced metalโ€“ligand covalency enable tunable NIR luminescence and red-light photoreduction.

@giacomo-morselli94.bsky.social & team find signs of doubletโ€“doublet annihilation, or excited-state disproportionation.

In @jacs.acspublications.org

pubs.acs.org/doi/10.1021/...

29.07.2025 07:20 โ€” ๐Ÿ‘ 19    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Postdoctoral Research Associate Applications are invited for a Postdoctoral Research Associate position to work under the supervision of Prof. Andrew Lawrence on a project funded by the Leverhulme Trust.

A postdoctoral position, funded by @leverhulme.ac.uk for up to 36 months, is available to join my group @edinburghchem.bsky.social. The project focuses on biomimetic approaches to natural product synthesis.

Deadline: 28th August 2025.

elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

29.07.2025 12:41 โ€” ๐Ÿ‘ 9    ๐Ÿ” 10    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Excited to share the latest work from David Anderson just accepted @angewandtechemie.bsky.social on the structure and applications of #sodium #neopentyl a donor free #organosodium #reagent soluble in #hydrocarbon solvents @unibe.ch

onlinelibrary.wiley.com/doi/epdf/10....

29.07.2025 17:12 โ€” ๐Ÿ‘ 53    ๐Ÿ” 11    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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#LCSOJournalClub is back after summer break with 2 articles and 3 preprints. | LCSO Lab #LCSOJournalClub is back after summer break with 2 articles and 3 preprints. 196.1 (Highlighted in picture): A chiral at cobalt catalyst developed by Eric Meggers and co-workers from Philipps-Universi...

Edition 196 of #LCSOJournalClub
www.linkedin.com/feed/update/...

29.07.2025 15:58 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The 6 first chapters of the Science of Synthesis Volume on hypervalent halogens in organic synthesis are now published in Chemistry at Thieme | LCSO Lab The 6 first chapters of the Science of Synthesis Volume on hypervalent halogens in organic synthesis are now published in Chemistry at Thieme Synthesis and Applications of Water-Soluble Hypervalent I...

The first 6 chapters of the Science of Synthesis Volume on hypervalent halogen compounds are now published:
www.linkedin.com/feed/update/...

28.07.2025 15:27 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Accelerated Discovery of Energy Transfer-Catalyzed Dearomative Cycloadditions through a Data-Driven Three-Layer Screening Strategy Visible-light-mediated energy transfer (EnT) photocatalysis has emerged as a highly appealing strategy for converting planar (hetero)arenes into complex, medicinally relevant, three-dimensional (3D) a...

๐Ÿš€Unlocking new frontiers in photocatalysis with AI!
Our latest @jacs.acspublications.org paper presents a 3๏ธโƒฃ-layer screening strategy for accelerated discovery of EnT-catalyzed dearomative cycloadditions! โœจ
Check this out: pubs.acs.org/doi/10.1021/...

#Photocatalysis #AIforScience #OrganicChemistry

25.07.2025 07:33 โ€” ๐Ÿ‘ 12    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We have an opening in our institute at #EPFL for a tenure-track assistant professor position.
Please repost...
www.epfl.ch/about/workin...

22.07.2025 13:26 โ€” ๐Ÿ‘ 27    ๐Ÿ” 22    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Great to see this work of @lcsolab.bsky.social alumni @mikusp.bsky.social published in @science.org !

18.07.2025 14:00 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Today in @science.org, @mikusp.bsky.social reports a method to replace the C2 of pyridines with N, affording pyridazines.

The change from electronically consonant (pyridine) to dissonant (pyridazine) opens retrosyntheses not typically available to the latter.

www.science.org/doi/10.1126/...

17.07.2025 23:13 โ€” ๐Ÿ‘ 40    ๐Ÿ” 10    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
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Breaking Kashaโ€™s Rule to Enable Higher Reactivity in Photoredox Catalysis Nearly all photochemical transformations known to date follow Kashaโ€™s rule, implying that reactions occur only from the lowest electronically excited state of a given spin multiplicity due to the fast...

We show how photoredox catalysis can bypass Kashaโ€™s rule, enabling reactions from higher excited states.

This work, led by the exceptional @bjoernpfund.bsky.social, offers new insights into photochemical reactivity.

Published in JACS @jacs.acspublications.org

bit.ly/3IysmjX

18.07.2025 07:00 โ€” ๐Ÿ‘ 37    ๐Ÿ” 12    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1
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Alternative Mechanism of Enzymatic Photocontrol by Azobenzene Azobenzene is a widely recognized tool for achieving artificial spatiotemporal control of enzyme activity through the use of light. Photocontrol reversibility is typically based on photostationary sta...

An unexplored avenue for azobenzene #photoswitching with simultaneous irradiation at 365:420 nm!
Congrats to Ranit, Alba and especially Caroline! @pubs.acs.org #ChemSky
Alternative Mechanism of Enzymatic Photocontrol by Azobenzene | ACS Catalysis pubs.acs.org/doi/10.1021/...

18.07.2025 10:53 โ€” ๐Ÿ‘ 10    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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#LCSOSynthesisProblem is back! | LCSO Lab #LCSOSynthesisProblem is back! This week, Jerome challenged us to four fascinating mechanism problems taken from the research of the groups of Sarpong, Lebold, Bouffard, Zhao, Zhang, and Dixneuf. ๐Ÿ’ก W...

Next edition of #LCSOSynthesisProblem
www.linkedin.com/feed/update/...

16.07.2025 06:16 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congrats and welcome at EPFL!

11.07.2025 14:40 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Huang Lab at EPFL

๐ŸŽ‰ Exciting News! ๐ŸŽ‰
Iโ€™m thrilled to share that I will be joining EPFL
as a tenure-track Assistant Professor in Chemical Engineering, starting July 1, 2026! The Huang Lab will explore the intersection polymer science and energy systems. huanglabepfl.com

11.07.2025 14:16 โ€” ๐Ÿ‘ 10    ๐Ÿ” 1    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Our paper on the synthesis of >50 iodine reagents, and the systematic analysis of their electrochemical properties, is just out in Synthesis @synthesis1969.bsky.social ๐Ÿคฉ

โš ๏ธFull disclosure: this is my very first paper without transition metals! ๐Ÿ˜œ read it here: www.thieme-connect.com/products/ejo...

10.07.2025 15:54 โ€” ๐Ÿ‘ 35    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@lcsolab is following 20 prominent accounts