Erh-Min Lai-IPMB

Now we have Chih-hang Wu @IPMBSinica Taiwan 🇹🇼 at #PPATH2025 — Fast and Furious: What happens after helper NLR immune receptors are activated to cause hypersensitive cell death.

See paper doi.org/10.1101/2025...

11.09.2025 13:29 — 👍 17    🔁 5    💬 0    📌 0

Connections are in action in Cologne! At #2025ISMPMI, the poster sessions aren’t just about groundbreaking research—they’re about meeting peers, collaboration, and sharing ideas that move plant-microbe science forward.

Full poster hours here: bit.ly/44LqCvc

#plantscience #networking

14.07.2025 16:25 — 👍 19    🔁 8    💬 1    📌 0

It was an amazing sciences day at #2025ISMPMI!
Right after the “Population, biology, ecology and genomics” session, I had the opportunity to have lunch and discuss about this topic with the co-chair @honour.bsky.social

14.07.2025 21:19 — 👍 12    🔁 3    💬 1    📌 0

Great pleasure hosting @fuquaclay.bsky.social visiting IPMB, Academia Sinica. Enjoy scientific discussion, casual chatting over delicious meals and outing. #Agrobacterium #Taiwan

07.06.2025 01:51 — 👍 0    🔁 0    💬 0    📌 0

Check out the ASM 10th Conference on Biofilms Bluesky page @asmbiofilms2025.bsky.social

18.12.2024 12:33 — 👍 3    🔁 2    💬 1    📌 0

Linear dicentric chromosomes in bacterial natural isolates reveal common constraints for replicon fusion | mBio Most bacterial genomes are monopartite with a single, circular chromosome. However, some species, like Agrobacterium tumefaciens, carry multiple chromosomes. Emergence of multipartite genomes is often...

Happy to share a new publication on a collaboration with Xindan Wang and @fuquaclay.bsky.social labs. We identified and characterized naturally occurring Agrobacterium strains with fused chromosomes. Did mobile genetic elements play a role in fusion? journals.asm.org/doi/10.1128/...

20.05.2025 14:37 — 👍 10    🔁 5    💬 1    📌 0

Quantitative dissection of Agrobacterium T-DNA expression in single plant cells reveals density-dependent synergy and antagonism - Nature Plants Alamos et al. show that Agrobacterium engages in density-dependent interactions that dictate transformation efficiency and transgene expression. These findings enable a quantitative model to improve m...

Interesting MS on Agrobacterium cooperation and antagonism as well as development of dual binary system that mitigates plant immune antagonism. www.nature.com/articles/s41...
www.nature.com/articles/s41...

16.05.2025 18:18 — 👍 20    🔁 7    💬 0    📌 0

Happy to write this News & Views highlighting a groundbreaking study on #Agrobacterium. By combining mathematical modelling with quantitative live-cell imaging, the study uncovered a density-dependent synergistic and antagonistic effect on #AMT

13.05.2025 14:22 — 👍 6    🔁 2    💬 1    📌 0

A plant dual-kinase protein traps a pathogen effector to trigger immunity - Nature Genetics Tandem kinase proteins (TKPs) are key regulators of plant immunity. We found that RWT4, a wheat TKP, confers resistance to the fungal pathogen Magnaporthe oryzae by directly recognizing the effector A...

Our Research Briefing on the tandem kinase proteins paper is online now!
Curious about the story behind our TKP paper?
📄 Research Briefing: www.nature.com/articles/s41...
📄 Research article: www.nature.com/articles/s41...

25.04.2025 18:30 — 👍 13    🔁 6    💬 0    📌 0

Floral Stage Optimization and Immune Evasion Enhance Agrobacterium-Mediated Genome Editing in Arabidopsis Agrobacterium-mediated transformation via floral inoculation (AMT-FI) enables genetic engineering without tissue culture. It is widely used in the model plant Arabidopsis thaliana, yet its efficiency ...

👀 EFR-mediated PTI restricts transient transformation and genome editing, but not T-DNA integration.
This study combines floral stage targeting 🌷, immune evasion 🛡️, and Agrobacterium engineering 🔧 to boost plant genome editing efficiency.
#Agrobacterium
#GenomeEditing
www.biorxiv.org/content/10.1...

09.05.2025 20:24 — 👍 2    🔁 2    💬 0    📌 0

Floral Stage Optimization and Immune Evasion Enhance Agrobacterium-Mediated Genome Editing in Arabidopsis Agrobacterium-mediated transformation via floral inoculation (AMT-FI) enables genetic engineering without tissue culture. It is widely used in the model plant Arabidopsis thaliana, yet its efficiency ...

Nice preprint from Erh-Min Lai's lab. "By integrating floral stage selection, immune evasion, and Agrobacterium engineering, this study provides a practical and versatile platform to advance plant genome engineering." vhttps://www.biorxiv.org/content/10.1101/2025.05.07.652770v1

09.05.2025 17:31 — 👍 11    🔁 5    💬 0    📌 0

Tweeps, please spread the word. We're still looking at recruiting a structural biologist (any level) to study plant-pathogen protein complexes especially in the context of coevolution. Direct inquiries welcome.

Please include a cover letter.

Applicant from US welcome? medium.com/@kamounlab/2...

09.05.2025 13:13 — 👍 35    🔁 63    💬 2    📌 1