Mehrad Hamidian

Acinetobacter variabilis represents a diverse species with novel regions associated with antibiotic resistance and surface polysaccharides Acinetobacter variabilis is an opportunistic pathogen found in both clinical and environmental settings with the potential to harbour and disseminate clinically significant antibiotic resistance genes...

Out now: www.microbiologyresearch.org/content/jour...

Pan-genus analysis and typing of antimicrobial resistance plasmids in Acinetobacter www.nature.com/articles/s44...

Phylogenomics, evolution and origin of multidrug-resistant Acinetobacter baumannii ST15 We studied the genomic evolution and transmission dynamics of multidrug-resistant ST15 (Institut Pasteur scheme) Acinetobacter baumannii, examining resistance gene acquisition, clonal diversification,...

New paper in Microbial Genomics!
Amazing work by @eradah.bsky.social & @liamtobin1.bsky.social & another great collaboration with François Lebreton & Patrick McGann. Here is the link: microbiologyresearch.org/content/jour...
#AMR #Acinetobacter
@aimi-uts.bsky.social

Genomic characteristics of the multiresistant Acinetobacter baumannii global clone 1 reference strain A297/RUH875

Just published in JAC!
We characterised the genomic features of the multi-resistant A. baumannii global clone 1 reference strain RUH875 — one of the earliest known isolates recovered in 1984 and an important genome for tracing the evolution of AMR in Ab. academic.oup.com/jac/article/... #AMR

We analysed >1,800 complete plasmids, uncovered 120 novel Rep types, and expanded the APT scheme to 257 types — now applicable across the entire genus.

The APT scheme offers a powerful new framework for tracking Acinetobacter plasmids in clinical and environmental settings.

🚨 New preprint out!
Pan-Genus Analysis and Typing of AMR Plasmids in Acinetobacter
Here, is the link: doi.org/10.21203/rs....
#AMR #Acinetobacter @liamtobin1.bsky.social @margaretlam.bsky.social @aimi-uts.bsky.social

Chromosomal capture of beneficial genes drives plasmids towards ecological redundancy Plasmids are a ubiquitous feature of bacterial genomes, but the evolutionary forces driving genes to become associated with plasmids are poorly understood. To address this problem, we compared the fit...

New pre-print!!! What types of genes end up on plasmids and why? The take home message of this paper is that beneficial genes move from plasmids to chromosome, causing the ecological value of plasmids to decay over time.
www.biorxiv.org/content/10.1...

Home A tool for generating consensus long-read assemblies for bacterial genomes - rrwick/Autocycler

New year, new assemblies!
I'm excited to announce Autocycler, my new tool for consensus assembly of long-read bacterial genomes!
It's the successor to Trycycler, designed to be faster and less reliant on user intervention.
Check it out: github.com/rrwick/Autoc...
(1/5)