Isaac Ostlund's Avatar

Isaac Ostlund

@isaacostlund.bsky.social

Scientist, writer, human. PhD Neurophysiologist, NIH specialist, researcher, game designer, and artist. Views are my own. DFTBA #NIH #NINDS #NIMH #BRAIN #neuro #neuroscience #science #research #neurons #SciFi #cognition

3,218 Followers  |  1,184 Following  |  24 Posts  |  Joined: 16.01.2024  |  1.8768

Latest posts by isaacostlund.bsky.social on Bluesky

As a viewer and not a player, I dont really have any experience or dog in this fight.

But this is the internet.

Balltops or you're trash.

#FGC #gaming

06.02.2025 02:59 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A white and gray landscape of cold ice, snow, and stone stretches into a horizon under a sea of stars on a clear night. A lone explorer sets up camp near his ship while a red planet orbits the alien world in the dark sky.

A white and gray landscape of cold ice, snow, and stone stretches into a horizon under a sea of stars on a clear night. A lone explorer sets up camp near his ship while a red planet orbits the alien world in the dark sky.

Cold Horizons

This is a #SciFi #digitalart #landscape I did. I've noticed a lot of my more recent work is aimed at a hopeful future, but also feels sort of lonely.

#art #oc

27.01.2025 17:37 โ€” ๐Ÿ‘ 44    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Energy sector shifts climate crisis responsibility to consumers The energy sector is creating a myth that individual action is enough to address climate change, University of Sydney research claims. Read more.

Research reveals that the energy sector is creating a myth that individual action is enough to address #climatechange. This shifts "responsibility" to consumers by casting the individuals as 'net-zero heroes', which reduces pressure on industry and government to take action.

#climate #science

22.01.2025 01:44 โ€” ๐Ÿ‘ 153    ๐Ÿ” 72    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 11
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Suicide rate higher for people with autism UQ-led research has found people on the autism spectrum are almost 3 times more likely to die by suicide compared to non-autistic people.

Research found that people on the #autism spectrum with low intellectual disability were over 3 times more likely to die by #suicide compared to people not on the autism spectrum.

These are people facing loneliness and invisible hardship that deserve more personal and systemic compassion

10.12.2024 17:16 โ€” ๐Ÿ‘ 150    ๐Ÿ” 49    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 10
Video thumbnail

#flourescent(almost)friday
(make sure to full screen this!) Some hippocampal neurons and dendritic arbors visualized from mCherry with a 3.6x objective in a SmartSPIM using iDisco.

05.12.2024 18:50 โ€” ๐Ÿ‘ 110    ๐Ÿ” 24    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
Neurons in adults are more "rigid" and require more stimulus to change. This is represented by a cartoon of neurons within an adult silhouette having straight and firm connections, opposed to the neurons within a child that have more flexible and adaptable connections.

Neurons in adults are more "rigid" and require more stimulus to change. This is represented by a cartoon of neurons within an adult silhouette having straight and firm connections, opposed to the neurons within a child that have more flexible and adaptable connections.

Some of my prior #research shows how certain adult neurons tied to reward resist change!

It is free access!

doi.org/10.3389/fnin...

On a macro level, this could provide a new hypothesis for why adults exhibit resistance to #learning, #anxiety, and #addiction.

#neuroscience #science ๐Ÿง ๐Ÿงช

02.12.2024 18:19 โ€” ๐Ÿ‘ 182    ๐Ÿ” 39    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 2

I have accepted an offer to work for the #NIH at the #BRAIN initiative!

The BRAIN Initiative has been a key inspiration for my progression as a neuroscientist and I am honored and excited to be a part of it!

#neuroscience ๐Ÿง ๐Ÿงช

02.12.2024 18:08 โ€” ๐Ÿ‘ 110    ๐Ÿ” 4    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 0

My apologies. It's a definition clarity error. When examining electrophysiology properties, especially plasticity, long term means timescales of minutes to hours. Thus "long-term depression" means a neuron's activity has been depressed for a few hours, which is a long time for a neuron.

27.11.2024 13:50 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

The paper is linked in the post, and its free open access!

GABA usually regulates dopamine. THC gets GABA #neurons stuck in an "off" position which then lets dopamine release more easily. If this goes on too long, the brain adjusts to higher dopamine and feels bad without it.

#neuroscience ๐Ÿง 

26.11.2024 16:29 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Great question. We did not examine the long-term outcomes of the animals. I did determine that a single exposure was insufficient to induce a long-lasting change. Young animals all exhibited long-term changes after a week of daily exposure, but only 50% of adults.

25.11.2024 21:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

We also found that the younger the age of exposure to marijuana (THC), the greater the effect and the faster the onset of long-term changes! ๐Ÿง 

#neuroscience #brain

25.11.2024 20:42 โ€” ๐Ÿ‘ 53    ๐Ÿ” 4    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0
A five progren green leaf. Very pretty! Waaait... Is that marijuana??

A five progren green leaf. Very pretty! Waaait... Is that marijuana??

We recently discovered that #marijuana (THC specifically) reduces GABA #neuron activity. This explains some of the rewarding effects of THC because the depression of GABA #neurons can lead to increased dopamine release, which can make us feel pretty good.

#science #EduSky

doi.org/10.3389/fnin...

25.11.2024 20:37 โ€” ๐Ÿ‘ 206    ๐Ÿ” 36    ๐Ÿ’ฌ 9    ๐Ÿ“Œ 6

#DFTBA

Excellent recommendation

23.11.2024 04:24 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Two futuristic spacecraft soar over a blue ocean in a canyon lined with majestic green cliffs. A sweeping misty and verdant landscape is touched with the clean and careful advancement of humankind as they explore new horizons.

Two futuristic spacecraft soar over a blue ocean in a canyon lined with majestic green cliffs. A sweeping misty and verdant landscape is touched with the clean and careful advancement of humankind as they explore new horizons.

Untapped Potential

This is a #scifi #digitalart piece I did a few years ago.

We have the potential to reach into the stars, find new technologies, save the planet, and so much more. But right now, it's unrealized. Will we make it? I want to feel hope, space exploration gives me that.

#art #future

23.11.2024 04:17 โ€” ๐Ÿ‘ 85    ๐Ÿ” 19    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Core memory unlocked. I forgot this book was everything to me for a few months when i was a child

22.11.2024 15:15 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thank you! Yes, how do starter packs work? And if I want to post into a group I use an emoji, did I see something about that?

22.11.2024 14:55 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

I'm a neuroscientist, about to leave research and academia and enter the NIH to spread awareness of new biotech and neuroscience developments. How do I get added?

22.11.2024 12:12 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Haha, yes! This describes my whole thesis from a few years back. I spent five years proving cocaine is addictive and more dangerous when you are a teen than when adult. Same for marijuana and certain other drugs.

Some things we already know, but need to be tested and proven anyway. #science !

22.11.2024 04:48 โ€” ๐Ÿ‘ 5    ๐Ÿ” 3    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Yes I have! But it has been a few years. I noticed his writing improved dramatically over the series. I bet his newer works continue that trend.

22.11.2024 04:41 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

Haha, thank you for the recommendation! I will have to give it a read

22.11.2024 04:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Two silhouettes stare at each other, an adult and a child. The brains of the two show inside as blue/white diagrams. The adult neurons have straight and rigid connections, while the child's brain has arcing and bending connections to illustrate flexibility and adaptability.

Two silhouettes stare at each other, an adult and a child. The brains of the two show inside as blue/white diagrams. The adult neurons have straight and rigid connections, while the child's brain has arcing and bending connections to illustrate flexibility and adaptability.

"On a macro level, our research could provide a new hypothesis for why adults exhibit greater resistance to learning, anxiety, and addiction compared to children and adolescents."

I made this image for a summary presentation I did a while back. #neuroscience #plasticity #science #digitalart #age

22.11.2024 04:09 โ€” ๐Ÿ‘ 73    ๐Ÿ” 16    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0

So i just click the art link on the right and can follow the whole thing there?

22.11.2024 03:40 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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How your gut microbiome is linked to depression and anxiety Gut microbiome: Key to health and mental well-being. Discover how these digestive tract microorganisms impact our bodies, beyond just causing diseases.

"You are what you eat" may be true, but also "what you eat is how you think." #depression #anxiety #neuroscience #EduSky

www.cas.org/resources/ca...

22.11.2024 03:05 โ€” ๐Ÿ‘ 98    ๐Ÿ” 39    ๐Ÿ’ฌ 7    ๐Ÿ“Œ 2

I'm a new user of #bluesky trying to get my feet under me. Does anyone have suggestions for scientists, #writers, and artist to follow or communities to join? Maybe the #writingcommunity can help.

Really any kind of science, fantasy or sci-fi, and also any sort of #art, #digitalart, or otherwise.

22.11.2024 02:51 โ€” ๐Ÿ‘ 61    ๐Ÿ” 16    ๐Ÿ’ฌ 14    ๐Ÿ“Œ 0
ORCID

Hello Dr. Monica, could you add me to the feed? I am brand new to bluesky and trying to figure it all out. Here is my orcid:

orcid.org/0000-0002-15...

22.11.2024 02:49 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@isaacostlund is following 17 prominent accounts