Renzo Gutierrez Loli

Zeus had his Hydra ⚔️, now Toxoplasma has its own.

Meet Hydra: not a monster, but a brand-new protein domain.
It multimerizes like crazy & rewrites the chromatin landscape 🧬 in Toxoplasma.

Our team and colleagues from @embl.org #Grenoble just dropped the preprint 👉
www.biorxiv.org/content/10.1...

Hydra domain drives SNF2L multimerization and marks ISWI diversification in parasites ISWI chromatin remodelers are conserved regulators of nucleosome positioning and chromatin accessibility across eukaryotes, yet their evolutionary diversification is poorly understood. In the apicompl...

I’m excited to share our new preprint!

We’ve been investigating a specific domain in TgSNF2L that forms decamers in vitro. Every time we attempted to break them apart, they just snapped back together. That tenacity earned it the nickname Hydra. 🐉

🔗 www.biorxiv.org/content/10.1...

📢 Big Announcement: Registration & abstract submission open for EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by ParaFrap @parafrap.bsky.social @embo.org

🗓️ 5-8 Oct 2025 - Les Embiez Island-France

🔚Deadline: 15 Jul 2025 meetings.embo.org/event/25-hos...

An ISWI-related chromatin remodeller regulates stage-specific gene expression in Toxoplasma gondii - Nature Microbiology Toxoplasma gondii evolved two ISWI remodellers, TgSNF2h and TgSNF2L. TgSNF2h forms a complex that insulates active genes, regulates MORC-driven sexual commitment and ensures precise gene expression, s...

Thrilled to share my first paper, now out in
@natmicrobiol.nature.com! Huge thanks to my amazing supervisor @hakimi.bsky.social and everyone who contributed to this work!

www.nature.com/articles/s41...

🔊 Calling all parasite enthusiasts - come join us to study Toxoplasma and Plasmodium organelle biology 🔬
www.jobs.gla.ac.uk/job/research...

Hola! Soy nuevo en Bluesky 🚀
Soy estudiante de doctorado en Inmunología y Enfermedades Infecciosas, y quiero conectar con más personas apasionadas por la #biología de parásitos. Hablemos de #microscopía, interacciones hospedero-patógeno, #neurociencia y todo lo que surja en el camino 🦠🧠🔬

📅 Save the Date! The EMBO Workshop "Host-Parasite Relationship: From Mechanisms to Control Strategies" organized by @ParaFrap will take place on October 5-8, 2025, at Les Embiez Island. Stay updated on registration opening —enter your email here: coming-soon.embo.org/w25-83 #Science #Parasite

Hi there! Just jumped from X to Bluesky! 🚀
I'm a senior PhD student in Immunology & Infectious Diseases, eager to connect with fellow #parasitology enthusiasts and chat about good #science and career insights. Let’s talk host-pathogen interactions, neuroscience, and everything in between! 🦠🧠🔬