Andrew Khodabukus

Guanfacine is an alpha-2 adrenoceptor agonist (relatively a2A selective)
Like tizanidine, it is oral only and causes less hypotension than clonidine and dexmedetomidine
This review examines potential use in delirium; they found case reports/open label series, but no RCTs

doi.org/10.1016/j.cc...

Deadline today!

By focusing on these areas, the contributors argue we can effectively harness the power of digital technology to improve patient care and address future challenges. 💡🏥📊

✅ Encourage a problem-driven approach to AI adoption, focusing on specific needs and rigorous evaluation. ✅ Foster a culture of patient engagement in co-design and data consent processes.

Recommendations:

✅ Invest in building data analytics teams within trusts to enable effective data utilisation. ✅ Prioritise funding for EPR maintenance, infrastructure development, and staff training.

5️⃣ Collaboration: Partnerships between NHS trusts, academia, and industry are vital to leverage expertise, funding, and accelerate progress. I would add #hospice too in this.

4️⃣ Patient Engagement: Involving patients in co-designing solutions and obtaining consent for data use is essential for building trust and ensuring solutions meet patient needs. Really important for ePaCCS

3️⃣ AI Integration: A strategic approach is needed for AI implementation. Focus on identifying specific problems and then finding suitable AI solutions, rather than adopting AI for its own sake. Will the LLM help to clinically code?

2️⃣ Workforce Training: Comprehensive training for staff on using EPRs effectively, including shortcuts and data coding, is crucial to maximise benefits and avoid inefficiencies. IMO it is usually only a one off event.

1️⃣ Data Maturity: Many NHS trusts lack digital maturity due to insufficient funding for EPR maintenance and infrastructure development. This leads to difficulties in extracting and using data effectively., even bigger in the third sector.

The NHS has made progress in digital transformation, particularly with electronic patient records (EPRs). However, the podcast argues a bottom-up approach is crucial for further advancement. We are the input.

Analogue to digital in the NHS: is the shift within reach? – with Holly Krelle and Erik Mayer Episode 49. Moving the NHS from analogue to digital is one of the health secretary's priorities. So, what will it take?

Analogue to digital in the NHS: is the shift within reach? – @healthfoundation.bsky.social podcast with Holly Krelle and Erik Mayer

🧵 NHS Digital Transformation: Bottom-Up Approach Is Key - a well timed podcast after and ePaCCS meeting.

United Kingdom palliative medicine higher sp specialty training applications open 10 am Thursday 14th November 2024 Close 4pm Thursday 5 December 2024 #choosepallmed HT ttps://ph s t r e c r u i t m e n t dot o r g.UK/specialties/palliative-medicine

📢 One week to go!
🪧 Train in Palliative Medicine in the United Kingdom
📅 Open 14 Nov 2024 - 5 Dec 2024
❔ Interviews 25 - 27 Mar 2025
👨‍⚕️ Start 6 Aug 2025
🌐 buff.ly/3Cun9Xj
@apmposts.bsky.social
#choosepallmed #palliativecare
buff.ly/3UXXPPL

Fantastic - the first of many from a great holistic practitioner! 🎉

Extension of the PRISMA 2020 statement for living systematic reviews (PRISMA-LSR): checklist and explanation Publications of living systematic reviews (LSRs) are increasing rapidly. Guidance facilitating transparent, complete, and accurate reporting of LSRs is needed. This paper reports the development of…

This BMJ article extends the PRISMA 2020 statement for living systematic reviews (PRISMA-LSR), providing a checklist and flow diagram to ensure transparent, complete, and accurate reporting of these reviews. Nice to see developing methodologies.

📢 The study highlights the urgent need for a clearer definition of palliative rehabilitation, increased funding, better care workflows, and enhanced professional training to improve care for individuals with incurable cancer. 💬📈🎓

6️⃣ Insufficient funding, poorly defined care workflows, and a lack of expertise among healthcare professionals were identified as key barriers to integration. 💰🛤️🧑‍🎓

5️⃣ Access to palliative rehabilitation is inconsistent and varies significantly based on geographic location. 🌍📍

4️⃣ Stakeholders agreed that palliative rehabilitation requires a multi-professional, interdisciplinary approach. 🤝👩‍⚕️👨‍⚕️

3️⃣ However, there was confusion about the distinction between palliative rehabilitation and palliative care.

2️⃣ Stakeholders agreed on the core components of palliative rehabilitation, viewing it as a holistic, goal-oriented approach to enhance the quality of life for patients with incurable cancer.

1️⃣ Only 12 out of 23 official documents described rehabilitation in the context of palliative care. 📋

Integration of palliative rehabilitation in cancer care: a multinational mixed method study - BMC Palliative Care Background Incurable cancer is a major contributor to societal suffering and disability, and palliative rehabilitation is recommended to be integrated within and between cancer services at all…

Integration of palliative rehabilitation in cancer care: a multinational mixed method study
https://palliativeprojects.eu/inspire/
The study examined official documents, conducted stakeholder interviews, and surveyed healthcare professionals. 📄

It's a great article and she was great with outcome measure stuff too!

8/ 🌟 Improving palliative care access can significantly benefit patients, families, and healthcare systems. It's time to act!
https://thewhpca.org/

7/ 🔍 Access to palliative care is also inequitable within high-income countries, influenced by socioeconomic status and ethnicity.
https://buff.ly/3AKFzCP

6/ 💡 The World Health Assembly's 2014 resolution aimed to improve palliative care, but progress has been slow. We need to prioritize this to reduce preventable suffering globally.
https://www.who.int/health-topics/palliative-care

5/ 🌐 Inequities in access to palliative care are growing. Regulatory constraints and fears of opioid misuse limit access to essential medicines in many LMICs.
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(24)00231-6/fulltext

4/ 🏥 Despite the benefits, only 14% of those who need palliative care receive it. For children, this figure is even lower at less than 3%.
https://www.paho.org/en/node/75063

3/ 💊 Palliative care includes physical, psychological, social, and spiritual support, improving quality of life for those with life-limiting conditions. It leads to better outcomes and lower costs.
https://journals.sagepub.com/doi/full/10.1177/26323524241263109