Melike Lakadamyali

YouTube video by The Children's Hospital of Philadelphia Baby KJ One Year Later: Gene-Editing Breakthrough Update

Baby KJ update! 🧪
He's looking so good now 🥹 Hope this little guy continues to thrive and that the team at CHOP gets to save more kids like him.🫶

youtu.be/dMY-nYMeis4?...

Seminar announcement for Max Planck Seminar Freiburg titled 'Super-resolution imaging of chromatin in health and disease' with date, time, location, and speaker Melike Lakadamyali from University of Pennsylvania Philadelphia USA

This Friday (today), we’re pleased to welcome Melike Lakadamyali (@melikel.bsky.social) from @upenn.edu.

If you are interested in Super resolution microscopy, cytoplasmic and nuclear organization with a focus on biophysics, then do not miss Prof. Lakadamyali talk in our lecture hall at 13:00. 🤗

Congratulations! So well deserved!

Congratulations! Incredibly well deserved!

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis - FocalPlane Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis -

Melike Lakadamyali @melikel.bsky.social, Jérôme Solon and Manuel Mendoza @longchrom.bsky.social share the behind the paper story of their research interrogating how chromosome compaction scales with cell size using a combination of live confocal microscopy and 3D STORM.

Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis - FocalPlane Seeing Chromatin Scaling with Cell Size, from Interphase to Mitosis -

Thanks to @focalplane.bsky.social for the invitation to highlight our recent @biophysj.bsky.social paper! With @melikel.bsky.social and Jérôme Solon, we combined super-resolution and live imaging to connect interphase chromatin organisation to mitotic chromosome compaction across cell sizes.

EMBL is deeply saddened by the passing of our Interim Director General Peer Bork, a pioneering scientist who left an indelible imprint on life science research in Europe and beyond.

We extend our deepest condolences to his family, friends, and colleagues.

www.embl.org/news/people-...

Feel better Rita!

Visualization of lysosomal membrane proteins by cryo electron tomography - Nature Communications Lysosomes are vital for cellular health and linked to many diseases. Here, authors use cryo-ET to image intact lysosomes and resolve lysosomal protein structures, providing a platform to advance the s...

I’m sad to miss the exciting talks at Cellbio! This is indeed a very exciting area of research. See also this fantastic paper by my Penn colleagues on this topic: www.nature.com/articles/s41...

Congratulations! So well deserved!

So proud to watch Jana turn a side quest into an entire research programme. Couldn’t imagine a more well-deserved outcome. 😍

The mighty yeast reveals what we believe are general principles of centromere evolution!

Behind the curtain: communities.springernature.com/posts/counti...

#MEvoSky 🧪🌎

Last call for Les Houches! Apply now or never! ;) (ok, in 2 years again then) and share with your friends.

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Erdinc Sezgin to Receive 2026 Early Independent Career Award
www.biophysics.org/news-room/er...

Congratulations @jiexiaolab.bsky.social . This is so well deserved.

Jie Xiao to Receive 2026 Carolyn Cohen Innovation Award
www.biophysics.org/news-room/ji...

Sarah Veatch to Receive 2026 Agnes Pockels Award in Lipids and Membrane Biophysics buff.ly/AdSMhCT

Congratulations to @ceesdekker.bsky.social . This is so well deserved!

Cornelis (Cees) Dekker to Receive the 2026 Kazuhiko Kinosita Award in Single-Molecule Biophysics buff.ly/fIexyZu

French-German WE-Heraeus-Seminar "Fluorescence markers for advanced microscopy : From photophysics to biology - 2026" March 15-20 2026, Les Houches, France

Please share: The application for Les Houches is open (until Oct 31)

fluorescenceleshouches.wordpress.com

*This is for you, if you ever wanted to learn all about fluorescence markers & how to apply them for your biological research!*

PS: no fees this year, you just need to get there, that's all!

Head of Scientific Instrumentation Workshops EMBL is a world leader in scientific research and at the forefront in the development of cutting-edge technologies. It operates across six sites in Heidelberg (headquarters), Barcelona, Cambridge, Gre...

@embl.org Heidelberg is looking for a new Head of Scientific Instrumentation! This is an exciting opportunity at the interface between scientific research and technology development, overseeing our mechanical and electronic workshops!
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Computational image analyst (m/f/d) The Max Planck Institute for Molecular Biomedicine in Münster, Germany, has an opening for a

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word 🙏 jobs.mpi-muenster.mpg.de/jobposting/0...

Mechanistic and Epigenetic Partitioning of Lamina-Associated Chromatin Revealed by a Genome-Wide Imaging Screen The nuclear periphery is a key site for heterochromatin organization in eukaryotic cells, where lamina-associated domains (LADs) promote transcriptional repression and genome stability. Despite their ...

🚨New preprint from the lab🚨
🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK.
www.biorxiv.org/content/10.1...

Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept ‪@embl.org
has an Independent faculty position. Fantastic place to set up your lab –great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

I will be here for a while. Let me know when you’re around. Would be great to catch up.

Want to acquire #ExM images like this and help us understand the true extent of cytoskeletal diversity across the tree of life? This position might be for you!

embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

With @dudinlab.bsky.social
@embl.org @biology-unige.bsky.social @moorefound.bsky.social

Thank you!

I’m excited to start my sabbatical at the EMBL in beautiful Heidelberg hosted by @sinemsaka.bsky.social Looking forward to learning more about DNA barcoding technologies, spatial omics, MINFLUX and more. Really excited about the exchange with all the amazing scientists at EMBL!

Congratulations Rita. It’s extremely well deserved. I wish you the best in your new role. You made a big impact at Nature Methods and have been an amazing supporter of novel microscopy and quantitative analysis methods. You will be missed.