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MRC MBU

@mrc-mbu.bsky.social

Research at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human disease

205 Followers  |  118 Following  |  9 Posts  |  Joined: 21.01.2025  |  1.8187

Latest posts by mrc-mbu.bsky.social on Bluesky

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So great to hear about some of the amazing work being done at the MRC Mitochondrial Biology Unit @mrc-mbu.bsky.social yesterday. There is much more today too.

Hopefully you have been able to catch up with some of the latest in #Mito research.

Open to MRC MBU members only.

17.10.2025 08:46 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Having a great Big Biology Day! ๐Ÿ˜Ž

11.10.2025 13:17 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Having fun enthusing young and old, expert and novice, about our mitochondria research at Cambridgeโ€™s Big Biology Day #PublicEngagement #Outreach @mrc-mbu.bsky.social

11.10.2025 12:01 โ€” ๐Ÿ‘ 9    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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#BigBiologyDay at Hills Road Sixth Form College- weโ€™re ready!

11.10.2025 08:31 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...

Exciting study from @frisophagy.bsky.social in @chinnery in the Chinnery lab @mrc-mbu.bsky.social. Congratulations to all authors involved in the study! #mitochondria

Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations | Science
www.science.org/doi/10.1126/...

09.10.2025 21:43 โ€” ๐Ÿ‘ 16    ๐Ÿ” 10    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
A montage of images of sixth form students in a Cambridge research lab

A montage of images of sixth form students in a Cambridge research lab

Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...

07.10.2025 12:43 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Judy Hirst awarded European Research Council Advanced Grant | MRC Mitochondrial Biology Unit Congratulations to Professor Judy Hirst, who has been awarded an Advanced Grant from the European Research Council (ERC). Judy's grant is for the energy-converting mechanism of a modular biomachine: U...

www.mrc-mbu.cam.ac.uk/news/judy-hi...

17.06.2025 14:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We look forward to welcoming Professor Mike Murphy @mrc-mbu.bsky.social at the @cambridgeuni.bsky.social as he delivers our first external seminar of the Easter term.

06.05.2025 07:57 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Ever wondered why eating something sugary gives you such an energy boost? ๐Ÿฐ

25.04.2025 10:14 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
Throwing a โ€˜spanner in the worksโ€™ of our cellsโ€™ machinery could help fight cancer, fatty liver diseaseโ€ฆ and hair loss Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the ‘powerhouses’ of our cells, allows us to make the fuel we need from s...

Throwing a โ€˜spanner in the worksโ€™ of our cellsโ€™ machinery could help fight cancer, fatty liver diseaseโ€ฆ and hair loss | EurekAlert! www.eurekalert.org/news-release...

18.04.2025 21:18 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture | EMBO Molecular Medicine imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...

Huge congrats to Pavel Nash on publishing his PhD work! ๐ŸŽ‰ We showcase a safer mtDNA gene therapy using a novel mtZFN architecture compatible with a single AAV. Thanks to the entire team! @mrc-mbu.bsky.social
@mbu-postdocs.bsky.social #MitochondrialDisease #mtDNA
www.embopress.org/doi/full/10....

09.04.2025 19:10 โ€” ๐Ÿ‘ 21    ๐Ÿ” 10    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Clinically translatable mitochondrial #GeneTherapy in muscle using tandem mtZFN architecture.
By P. Nash, @mitogene.bsky.social & colleagues @mrc-mbu.bsky.social

๐Ÿ—ž๏ธ doi.org/10.1038/s443...

Read also related N&V by A. Ghifari & M. Ott ๐Ÿ‘‰ doi.org/10.1038/s443...

11.04.2025 14:36 โ€” ๐Ÿ‘ 7    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Looking forward for this exciting meeting in Malta!!! Would be fun with lot of exciting Science!!

26.03.2025 11:40 โ€” ๐Ÿ‘ 10    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Well done everyone! ๐Ÿ˜Ž

24.03.2025 13:17 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Wishing our team and all our visitors a great day! ๐Ÿงฌ๐Ÿฅผ

22.03.2025 10:56 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Batten Disease Global Research Initiative Grant for Kasparas Petkevicius | MRC Mitochondrial Biology Unit Congratulations to Kasparas Petkevicius, who has been awarded a grant of $50,000 from the Batten Disease Global Research Initiative, which will fund a research project โ€œExploring the efficacy of bis(m...

Congratulations Kasparas! ๐Ÿ˜Ž๐Ÿ‘

www.mrc-mbu.cam.ac.uk/news/batten-...

19.03.2025 16:59 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Check out this exciting @faseborg.bsky.social conference with some top quality speakers, talking about #mito DNA mutation & repair! @mrc-mbu.bsky.social @mrcmitocluster.bsky.social
@mbu-postdocs.bsky.social @jellevda.bsky.social @ritahorvath.bsky.social @mito-news.bsky.social

05.03.2025 18:44 โ€” ๐Ÿ‘ 4    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What a fabulous week that was! ๐Ÿ˜Ž

04.03.2025 14:23 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@jellevda.bsky.social @ritahorvath.bsky.social @londonmito.bsky.social @mitonewcastle.bsky.social @lilyfoundation.bsky.social @mito-news.bsky.social @mitowomen.bsky.social @mrc-mbu.bsky.social @needhamneuro.bsky.social @cuhnhs.bsky.social @uniofcam.bsky.social @mrcmitocluster.bsky.social

28.02.2025 11:01 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Cambridge signs sustainable research agreement.
www.mrc-mbu.cam.ac.uk/news/cambrid...

17.02.2025 11:51 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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LifeArc on LinkedIn: Rare disease research faces unique challenges including lack ofโ€ฆ Rare disease research faces unique challenges including lack of investment, small patient populations, fragmented research and challenging routes toโ€ฆ

Very excited to share this #LifeArc video about the 4 new #rare disease centres across the UK, with our centre for #mitochondrial diseases being one of them!

@jellevda.bsky.social @ritahorvath.bsky.social @frisophagy.bsky.social @mrc-mbu.bsky.social

www.linkedin.com/posts/lifear...

29.01.2025 10:54 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Hello! ๐Ÿ‘‹
We've joined the Bluesky community to connect again with all those interested in #mitochondria. ๐Ÿ˜Ž๐Ÿฅผ๐Ÿ”ฌ๐Ÿ‘ฉโ€๐Ÿ”ฌ๐Ÿ‘จโ€๐Ÿ”ฌ๐Ÿงช

21.01.2025 13:37 โ€” ๐Ÿ‘ 12    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

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