MRC MBU's Avatar

MRC MBU

@mrc-mbu.bsky.social

Research at the MRC Mitochondrial Biology Unit is focussed on the involvement of mitochondria and their dysfunction in an ever-increasing range of human disease

218 Followers  |  118 Following  |  9 Posts  |  Joined: 21.01.2025
Posts Following

Posts by MRC MBU (@mrc-mbu.bsky.social)

Post image

So great to hear about some of the amazing work being done at the MRC Mitochondrial Biology Unit @mrc-mbu.bsky.social yesterday. There is much more today too.

Hopefully you have been able to catch up with some of the latest in #Mito research.

Open to MRC MBU members only.

17.10.2025 08:46 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Post image Post image Post image Post image

Having a great Big Biology Day! 😎

11.10.2025 13:17 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Having fun enthusing young and old, expert and novice, about our mitochondria research at Cambridge’s Big Biology Day #PublicEngagement #Outreach @mrc-mbu.bsky.social

11.10.2025 12:01 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Post image Post image Post image

#BigBiologyDay at Hills Road Sixth Form College- we’re ready!

11.10.2025 08:31 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations Mitochondrial synthesis of adenosine triphosphate is essential for eukaryotic life but is dependent on the cooperation of two genomes: nuclear and mitochondrial DNA (mtDNA). mtDNA mutates ~15 times as...

Exciting study from @frisophagy.bsky.social in @chinnery in the Chinnery lab @mrc-mbu.bsky.social. Congratulations to all authors involved in the study! #mitochondria

Ubiquitin-mediated mitophagy regulates the inheritance of mitochondrial DNA mutations | Science
www.science.org/doi/10.1126/...

09.10.2025 21:43 β€” πŸ‘ 16    πŸ” 9    πŸ’¬ 2    πŸ“Œ 0
A montage of images of sixth form students in a Cambridge research lab

A montage of images of sixth form students in a Cambridge research lab

Applications now open for our work experience programme for year 12 students, run with @mrc-mbu.bsky.social & @stcatharines.bsky.social We give students a valuable insight into life as a research scientist and student in Cambridge. Details & application link here: www.cimr.cam.ac.uk/inspiring-sc...

07.10.2025 12:43 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
Judy Hirst awarded European Research Council Advanced Grant | MRC Mitochondrial Biology Unit Congratulations to Professor Judy Hirst, who has been awarded an Advanced Grant from the European Research Council (ERC). Judy's grant is for the energy-converting mechanism of a modular biomachine: U...

www.mrc-mbu.cam.ac.uk/news/judy-hi...

17.06.2025 14:54 β€” πŸ‘ 1    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Post image

We look forward to welcoming Professor Mike Murphy @mrc-mbu.bsky.social at the @cambridgeuni.bsky.social as he delivers our first external seminar of the Easter term.

06.05.2025 07:57 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Ever wondered why eating something sugary gives you such an energy boost? 🍰

25.04.2025 10:14 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
Throwing a β€˜spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the ‘powerhouses’ of our cells, allows us to make the fuel we need from s...

Throwing a β€˜spanner in the works’ of our cells’ machinery could help fight cancer, fatty liver disease… and hair loss | EurekAlert! www.eurekalert.org/news-release...

18.04.2025 21:18 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Preview
Clinically translatable mitochondrial gene therapy in muscle using tandem mtZFN architecture | EMBO Molecular Medicine imageimageEfficient mitochondrial gene therapy is achieved with a novel tandem zinc finger nuclease (mtZFN) architecture delivered via adeno-associated viral (AAV) vectors, significantly reducing mutation loads in muscle tissue and rescuing ...

Huge congrats to Pavel Nash on publishing his PhD work! πŸŽ‰ We showcase a safer mtDNA gene therapy using a novel mtZFN architecture compatible with a single AAV. Thanks to the entire team! @mrc-mbu.bsky.social
@mbu-postdocs.bsky.social #MitochondrialDisease #mtDNA
www.embopress.org/doi/full/10....

09.04.2025 19:10 β€” πŸ‘ 21    πŸ” 10    πŸ’¬ 1    πŸ“Œ 2
Post image

Clinically translatable mitochondrial #GeneTherapy in muscle using tandem mtZFN architecture.
By P. Nash, @mitogene.bsky.social & colleagues @mrc-mbu.bsky.social

πŸ—žοΈ doi.org/10.1038/s443...

Read also related N&V by A. Ghifari & M. Ott πŸ‘‰ doi.org/10.1038/s443...

11.04.2025 14:36 β€” πŸ‘ 7    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Looking forward for this exciting meeting in Malta!!! Would be fun with lot of exciting Science!!

26.03.2025 11:40 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Well done everyone! 😎

24.03.2025 13:17 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Wishing our team and all our visitors a great day! 🧬πŸ₯Ό

22.03.2025 10:56 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Batten Disease Global Research Initiative Grant for Kasparas Petkevicius | MRC Mitochondrial Biology Unit Congratulations to Kasparas Petkevicius, who has been awarded a grant of $50,000 from the Batten Disease Global Research Initiative, which will fund a research project β€œExploring the efficacy of bis(m...

Congratulations Kasparas! πŸ˜ŽπŸ‘

www.mrc-mbu.cam.ac.uk/news/batten-...

19.03.2025 16:59 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

Check out this exciting @faseborg.bsky.social conference with some top quality speakers, talking about #mito DNA mutation & repair! @mrc-mbu.bsky.social @mrcmitocluster.bsky.social
@mbu-postdocs.bsky.social @jellevda.bsky.social @ritahorvath.bsky.social @mito-news.bsky.social

05.03.2025 18:44 β€” πŸ‘ 4    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

What a fabulous week that was! 😎

04.03.2025 14:23 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@jellevda.bsky.social @ritahorvath.bsky.social @londonmito.bsky.social @mitonewcastle.bsky.social @lilyfoundation.bsky.social @mito-news.bsky.social @mitowomen.bsky.social @mrc-mbu.bsky.social @needhamneuro.bsky.social @cuhnhs.bsky.social @uniofcam.bsky.social @mrcmitocluster.bsky.social

28.02.2025 11:01 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
Post image

Cambridge signs sustainable research agreement.
www.mrc-mbu.cam.ac.uk/news/cambrid...

17.02.2025 11:51 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
LifeArc on LinkedIn: Rare disease research faces unique challenges including lack of… Rare disease research faces unique challenges including lack of investment, small patient populations, fragmented research and challenging routes to…

Very excited to share this #LifeArc video about the 4 new #rare disease centres across the UK, with our centre for #mitochondrial diseases being one of them!

@jellevda.bsky.social @ritahorvath.bsky.social @frisophagy.bsky.social @mrc-mbu.bsky.social

www.linkedin.com/posts/lifear...

29.01.2025 10:54 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1

Hello! πŸ‘‹
We've joined the Bluesky community to connect again with all those interested in #mitochondria. 😎πŸ₯ΌπŸ”¬πŸ‘©β€πŸ”¬πŸ‘¨β€πŸ”¬πŸ§ͺ

21.01.2025 13:37 β€” πŸ‘ 12    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0