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@protpapers.bsky.social

πŸ€– Feed for papers about HLA/MHC neoantigens, immunopeptidomes and HDX-MS from PubMed and bioRxiv. Run by @ab604.uk inspired by @phypapers.bsky.social and https://bsky.app/profile/r-bloggers.bsky.social. Code: https://github.com/ab604/prot-paper-bot

48 Followers  |  1 Following  |  409 Posts  |  Joined: 02.09.2024  |  1.4025

Latest posts by protpapers.bsky.social on Bluesky


Non-Enzymatic Structural Modifications Reshape Peptide Presentation and Antigen Recognition

https://www.biorxiv.org/content/10.1101/2025.11.06.687013v1

08.11.2025 05:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Immunopeptidomics can inform the design of mRNA vaccines for the delivery of Mycobacterium tuberculosis MHC class II antigens https://pubmed.ncbi.nlm.nih.gov/41191777/

06.11.2025 05:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Investigating the conformational landscape of human histidine-rich glycoprotein using amide HDX-MS https://pubmed.ncbi.nlm.nih.gov/41190777/

05.11.2025 17:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Epitope mapping of diagnostic antibodies targeting SARS-CoV-2 nucleocapsid protein using hydrogen-deuterium exchange mass spectrometry https://pubmed.ncbi.nlm.nih.gov/41126529/

05.11.2025 05:40 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


In vitro Characterization of Peptidomimetic Proteolysis Targeting Chimera (PROTAC) as a Degrader of 3-Chymotrypsin-Like Protease (Mpro/3CLpro) against SARS-CoV-2

https://www.biorxiv.org/content/10.1101/2025.10.30.685646v1

03.11.2025 17:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Data-Independent Immunopeptidomics Discovery of Low-Abundant Bacterial Epitopes https://pubmed.ncbi.nlm.nih.gov/41166551/

31.10.2025 05:39 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


A Unified Protein Embedding Model with Local and Global Structural Sensitivity

https://www.biorxiv.org/content/10.1101/2025.10.27.684815v1

28.10.2025 05:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Comprehensive Internal Standards for Hydrogen-Deuterium Exchange Mass Spectrometry https://pubmed.ncbi.nlm.nih.gov/41140027/

27.10.2025 17:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


PeptiLine: an interactive platform for customizable functional peptidomic analysis

https://www.biorxiv.org/content/10.1101/2025.10.23.684139v1

26.10.2025 17:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


Pan-cancer analysis reveals that tumor microbiomes generate specific epitopes through transcriptional reprogramming

https://www.biorxiv.org/content/10.1101/2025.10.22.683275v1

25.10.2025 05:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes https://pubmed.ncbi.nlm.nih.gov/41130749/

24.10.2025 17:38 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Mapping the structural dynamics of red- and blue-emitting beetle luciferases revealed by HDX-MS https://pubmed.ncbi.nlm.nih.gov/41130797/

24.10.2025 05:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Epitope Mapping of Diagnostic Antibodies Targeting SARS-CoV-2 Nucleocapsid Protein Using Hydrogen-Deuterium Exchange Mass Spectrometry https://pubmed.ncbi.nlm.nih.gov/41126529/

23.10.2025 17:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Immunopeptidome analysis reveals SERPINB3 as an autoantigen driving eczematized psoriasis https://pubmed.ncbi.nlm.nih.gov/41124250/

23.10.2025 05:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Methionine Oxidation Footprinting in Intact Proteins (MOFIP) Using Top-Down Proteomics https://pubmed.ncbi.nlm.nih.gov/41116609/

22.10.2025 17:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Utilizing Protein Bioinformatics to Delve Deeper into Immunopeptidomic Datasets with AIMS: An Automated Immune Molecule Separator https://pubmed.ncbi.nlm.nih.gov/41085626/

21.10.2025 05:40 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

A Novel Machine Learning Post-processing Filter for Mass Spectrometry-Based Proteogenomics Leveraging Retention Time Deviation and Peptide Physicochemical Properties https://pubmed.ncbi.nlm.nih.gov/41085625/

20.10.2025 17:40 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Characterization of Human Leukocyte Antigen (HLA) Proteins with Integrated Immunopeptidomics and Proteomics Approach https://pubmed.ncbi.nlm.nih.gov/41085623/

20.10.2025 05:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

High-Coverage Immunopeptidomics Using timsTOF Mass Spectrometers with Thunder-DDA-PASEF Boosted by MS(2)Rescore https://pubmed.ncbi.nlm.nih.gov/41085619/

19.10.2025 17:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Targeted Analyses of MHC-I Peptides Using TOMAHAQ https://pubmed.ncbi.nlm.nih.gov/41085618/

19.10.2025 05:39 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Epitope Screening by Hydrogen-Deuterium Exchange Mass Spectrometry for Improved Immunotherapeutic Outcomes https://pubmed.ncbi.nlm.nih.gov/41085634/

16.10.2025 17:38 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Mapping Hydrogen Migration Thresholds for Site-Specific HDX-MS https://pubmed.ncbi.nlm.nih.gov/41067539/

10.10.2025 05:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


Targeting Kinases to Reshape the Immunopeptidome landscape in Chronic Myeloid Leukemia

https://www.biorxiv.org/content/10.1101/2025.10.07.680859v1

09.10.2025 05:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


Identification of Expressed Endogenous Retroviral Element Associated Long Terminal Repeats in Devil Facial Tumour Cells

https://www.biorxiv.org/content/10.1101/2025.10.06.679394v1

08.10.2025 17:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Recurrent immunogenic neoantigens and their cognate T-cell receptors in treatment-resistant metastatic prostate cancer https://pubmed.ncbi.nlm.nih.gov/41056506/

08.10.2025 05:37 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


Assembly and substrate engagement mechanism of the bacterial proteasome activator Boa

https://www.biorxiv.org/content/10.1101/2025.10.01.679806v1

02.10.2025 05:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Immunopeptidomics informs discovery and delivery of Mycobacterium tuberculosis MHC-II antigens for vaccine design https://pubmed.ncbi.nlm.nih.gov/41031036/

01.10.2025 17:37 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0


Genetic landscape of DNMT3A R882H reveals mechanism of aberrant oligomerization

https://www.biorxiv.org/content/10.1101/2025.09.24.678339v1

28.09.2025 17:31 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Immunopeptidome Landscape During Brucella melitensis Infection in Mice https://pubmed.ncbi.nlm.nih.gov/41009442/

28.09.2025 05:36 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Framework for analyzing MAE-derived immunopeptidomes from cell lines with shared HLA haplotypes https://pubmed.ncbi.nlm.nih.gov/40996974/

27.09.2025 05:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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