Alexander Hogrebe, PhD's Avatar

Alexander Hogrebe, PhD

@alexhgo.bsky.social

Data Scientist at MSAID 🪄 Phospho-proteomics and MS tech 🔬 He/him 🏳️‍🌈 Tooting privately on Mastodon @AlexHgO@fediscience.org 🐘

929 Followers  |  382 Following  |  107 Posts  |  Joined: 18.08.2023  |  2.3033

Latest posts by alexhgo.bsky.social on Bluesky

Thema heute ist Wissenschaft als Beruf. Ein großes Thema auf Bsky und in der Wissenschaft ist das unsägliche #WissZVG und die Probleme, die für #IchbinHanna und #IchbinReyhan daraus entstehen. Dazu haben @amreibahr.bsky.social, @drkeichhorn.bsky.social, @kubon.bsky.social uva geschrieben

10.10.2025 07:42 — 👍 42    🔁 8    💬 2    📌 0
ACHTUNG! #Unkürzbar Demo hat einen neuen Startpunkt. 10.10. 14:00 Zimmerstraße

ACHTUNG! #Unkürzbar Demo hat einen neuen Startpunkt. 10.10. 14:00 Zimmerstraße

#Berlin spart sich kaputt – auch beim Klima. Die geplanten Kürzungen im Haushalt bedrohen zentrale Programme wie das Berliner Energie- und Klimaschutzprogramm. Heute wird ab 14:00 gegen die Kürzungspläne demonstriert. Der #Klimablock trifft sich beim Heißluftballon der “Welt”.

10.10.2025 06:56 — 👍 13    🔁 3    💬 0    📌 2

Do you have an exciting experiment that you'd love to do using proteomics in the context of your work? YPIC funds 5000 eur for your research idea to come to life!

⬇️⬇️⬇️⬇️⬇️

06.10.2025 06:08 — 👍 5    🔁 7    💬 1    📌 0

Please - stop doing the screenshot no link thing on Bluesky. This platform does not punish you for posting a URL. You picked up the habit from Meta apps? Stop doing Mark Z's bidding. Link ESPECIALLY to authors, reporters, bloggers, etc. where you quote the work.

30.09.2025 18:52 — 👍 6708    🔁 1525    💬 83    📌 81
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🌟 Students in Europe — want to run your own proteomics experiment?
Apply for the Student Proteomics Fund and get €5000 to make it happen!
No proteomics experience needed — just a strong idea.
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01.10.2025 06:25 — 👍 4    🔁 5    💬 1    📌 1

If you've ever watched Sabine #Hossenfelder and felt the vibes were off, this one is for you. Still a bit shell shocked from the final book blurb

30.09.2025 21:25 — 👍 7    🔁 1    💬 0    📌 0
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We’re excited to invite you to a career panel discussion featuring three outstanding speakers: Rudolf Aebersold, Marcus Bantschoff, Pascal Gaudet
📅 Date: November 27
⏰ Time: 2:00 PM
Don't miss it out and hear the inspiration from leaders in the field!
👉 Register here: docs.google.com/forms/d/e/1F...

22.09.2025 09:59 — 👍 6    🔁 6    💬 0    📌 0

Diese #Klimademo war laut, bunt, wütend, hoffnungsvoll - ich bin stolz auf dich #Berlin, weiter so 💪🏻

20.09.2025 13:35 — 👍 48    🔁 14    💬 1    📌 0
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Only single cell sequencing of the all these post docs will reveal why

19.09.2025 08:54 — 👍 353    🔁 46    💬 8    📌 6
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Tfw u scream into the abyss and abyss screams back 〰️😱😱〰️ #whitegrunt #mouthoff #mouthfight #grunt #gruntfight #screamingintotheabyss #staghorn #acerventura #coral #coralhead #coralcitycamera #miami #portmiami #biscaynebay #coralcity

19.09.2025 16:21 — 👍 509    🔁 86    💬 5    📌 9

Morgen ist #Klimademo. Wir sind auch dabei.
👉 #Berlin: 12:00 Invalidenpark
👉 #Potsdam: 13:00 Magnus-Zeller-Platz
In Berlin auch mit einem Stand am Invalidenpark (12-13 Uhr). Kommt gerne vorbei und sprecht mit uns.
#ExitGasEnterFuture #DrawTheLine

19.09.2025 07:56 — 👍 9    🔁 6    💬 0    📌 0
Preview
Europe’s summer of extreme weather caused €43bn of short-term losses, analysis finds Greatest damage from heat, drought and flooding done in Cyprus, Greece, Malta and Bulgaria

Failing to address climate change is very expensive.

19.09.2025 08:37 — 👍 379    🔁 152    💬 5    📌 9
Preview
Tipsy bats and perfect pasta: Ig Nobels celebrate ‘improbable’ research The annual awards are a celebration of weird but thought-provoking science.

Highlights of this year’s Ig Nobel recipients include a nutrition prize for studying the preferred pizza toppings of rainbow lizards at a seaside resort in Togo

go.nature.com/4n5HQv7

19.09.2025 09:27 — 👍 62    🔁 24    💬 0    📌 6
Preview
The Ozone Hole Is Steadily Shrinking because of Global Efforts After nearly 40 years of global efforts, the ozone hole over Antarctica is continuing to heal

A little bit of good news for you. And a reminder that we *can* solve big, global problems--when we want to. 🧪

(by @meghanbartels.bsky.social)

16.09.2025 19:59 — 👍 302    🔁 113    💬 11    📌 8

Ich bin dabei #ExitGasEnterFuture

12.09.2025 12:15 — 👍 3    🔁 0    💬 0    📌 0

Am Samstag findet die #LangeNachtdesKlimas statt. Wir sind zusammen mit @architects4future.bsky.social und @s4f-de-fg-bauen.bsky.social ab 16h mit einem Stand vertreten. Dort erfahrt ihr u.a. etwas über die Initiative #HouseEurope www.houseeurope.eu/de/. Weitere Infos: www.langenachtdesklimas.de

12.09.2025 08:35 — 👍 27    🔁 16    💬 1    📌 0

Genervt von Katherina Reiche, frustriert über Klimazerstörung, abgefuckt von fossilen Konzernen? Wie wär's mit Klimademo am 20.09.? 🤝
#ExitGasEnterFuture, in über 60 Städten deutschlandweit!

12.09.2025 11:34 — 👍 222    🔁 67    💬 8    📌 1

Do you or your lab use the Skyline software for #MassSpectrometry #proteomics? I'm looking for instructors to help with this year's Skyline Online, a virtual workshop/crash-course for all things Skyline! I'm especially looking for early career researchers for this opportunity. Please DM!

06.09.2025 17:11 — 👍 10    🔁 12    💬 0    📌 0

My thought upon watching was "queerest movie without any queer content" I've seen in quite a while. Very entertaining

05.09.2025 07:18 — 👍 3    🔁 0    💬 0    📌 0
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Join us for our 19th YPIC Webinar – “Transition from Academia to Start-Up”

Ever wondered what it takes to turn your research into a company?! 🧪

Information in comments!
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#YPIC #Proteomics #ScienceToStartup #ScienceCareers #Entrepreneurship #Biotech #AcademicTransition #Webinar #StartUpScience

04.09.2025 09:06 — 👍 14    🔁 5    💬 1    📌 4

Google won’t be forced to sell its Chrome browser and can keep paying companies to keep its search engine as the default on smartphones, thanks to a federal ruling.

In other words? Google gets to remain a monopoly and keep its harmful, anti-competitive practices.

Shameful.

03.09.2025 21:31 — 👍 9514    🔁 2288    💬 378    📌 129
Preview
Klimademo 20.09.2025 | Fridays for Future Mobi-Material Demo finden Unterstützen Hintergrund Profilbildgenerator Während die Klimakrise weltweit Existenzen zerstört, heizt die Bundesregierung sie weiter an: Neue Gasbohrungen in der Nordsee, n...

Deine Straße ist zu langweilig? Wir haben was für dich: Bei uns kannst du jetzt gratis Sticker, Plakate und Postkarten bestellen und alle von den Klimademos am 20. September wissen lassen! Einfach hier bestellen: fridaysforfuture.de/klimastreik/...

02.09.2025 07:47 — 👍 107    🔁 49    💬 0    📌 0

Haha, you could tell they had fun getting creative xD

01.09.2025 10:40 — 👍 2    🔁 0    💬 0    📌 0

Another targeted blow against academia. Though it's always been wild to me how long US PhD programs can take. 6 years is just insanely long. It's good for you if you want to compete in academia, but wasted time (and underpayment) for most others

30.08.2025 07:13 — 👍 0    🔁 0    💬 0    📌 0

I didn't either, but it was a fun surprise when I checked the wiki a decade later xD

Oh, and I didn't know! Yeah I doubt they're well adjusted to modern controls... But cool that it still can be played at all this way

28.08.2025 21:01 — 👍 1    🔁 0    💬 0    📌 0

The opening sequence of this game (arriving in the facility by train, exploring it, talking to colleagues and getting introduced to the Anti-MS) is seared into my brain. This was such a masterpiece of building suspense to a game starting catastrophe

28.08.2025 20:39 — 👍 0    🔁 0    💬 1    📌 0
The Anti-Mass Spectrometer from the computer game Half-Life moments before the Resonance Cascade.

The Anti-Mass Spectrometer from the computer game Half-Life moments before the Resonance Cascade.

The Anti-Mass Spectrometer during the Resonance Cascade.

The Anti-Mass Spectrometer during the Resonance Cascade.

The Anti-Mass Spectrometer after the Resonance Cascade.

The Anti-Mass Spectrometer after the Resonance Cascade.

Description of the Anti-Mass Spectrometer from the official Half-Life wiki.

Description of the Anti-Mass Spectrometer from the official Half-Life wiki.

My favorite one is the "Anti-Mass Spectrometer" from legendary computer game Half-Life. Physicist Gordon Freeman measures an alien sample in it, which triggers the "Resonance Cascade" that causes aliens to take over the research facility. No mention unfortunately of the "Anti-Proteome"

28.08.2025 20:36 — 👍 3    🔁 0    💬 2    📌 0

I think it was @cashwood.proteaglyco.com ? But still, great scene xD

28.08.2025 18:36 — 👍 3    🔁 0    💬 1    📌 0

Eine unglaubliche Frechheit, danke für euren Einsatz 👏🏻

28.08.2025 10:28 — 👍 0    🔁 0    💬 0    📌 0
My resignation letter from CDC.  

Dear Dr. Houry,

I am writing to formally resign from my position as Director of the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention (CDC), effective August 28, 2025, close of business.   I am happy to stay on for two weeks to provide transition, if requested.

This decision has not come easily, as I deeply value the work that the CDC does in safeguarding public health and am proud of my contributions to that critical mission. However, after much contemplation and reflection on recent developments and perspectives brought to light by Secretary Robert F. Kennedy Jr., I find that the views he and his staff have shared challenge my ability to continue in my current role at the agency and in the service of the health of the American people. Enough is enough.

While I hold immense respect for the institution and my colleagues, I believe that it is imperative to align my professional responsibilities to my system of ethics and my understanding of the science of infectious disease, immunology, and my promise to serve the American people.  This step is necessary to ensure that I can contribute effectively in a capacity that allows me to remain true to my principles.

My resignation letter from CDC. Dear Dr. Houry, I am writing to formally resign from my position as Director of the National Center for Immunization and Respiratory Diseases at the Centers for Disease Control and Prevention (CDC), effective August 28, 2025, close of business. I am happy to stay on for two weeks to provide transition, if requested. This decision has not come easily, as I deeply value the work that the CDC does in safeguarding public health and am proud of my contributions to that critical mission. However, after much contemplation and reflection on recent developments and perspectives brought to light by Secretary Robert F. Kennedy Jr., I find that the views he and his staff have shared challenge my ability to continue in my current role at the agency and in the service of the health of the American people. Enough is enough. While I hold immense respect for the institution and my colleagues, I believe that it is imperative to align my professional responsibilities to my system of ethics and my understanding of the science of infectious disease, immunology, and my promise to serve the American people. This step is necessary to ensure that I can contribute effectively in a capacity that allows me to remain true to my principles.

The recent change in the adult and children’s immunization schedule threaten the lives of the youngest Americans and pregnant people.   The data analyses that supported this decision have never been shared with CDC despite my respectful requests to HHS and other leadership.  This lack of meaningful engagement was further compounded by a “frequently asked questions” document written to support the Secretary’s directive that was circulated by HHS without input from CDC subject matter experts and that cited studies that did not support the conclusions that were attributed to these authors.  Having worked in local and national public health for years, I have never experienced such radical non-transparency, nor have I seen such unskilled manipulation of data to achieve a political end rather than the good of the American people.

It is untenable to serve in an organization that is not afforded the opportunity to discuss decisions of scientific and public health importance released under the moniker of CDC.  The lack of communication by HHS and other CDC political leadership that culminates in social media posts announcing major policy changes without prior notice demonstrate a disregard of normal communication channels and common sense.  Having to retrofit analyses and policy actions to match inadequately thought-out announcements in poorly scripted videos or page long X posts should not be how organizations responsible for the health of people should function.  Some examples include the announcement of the change in the COVID-19 recommendations for children and pregnant people, the firing of scientists from ACIP by X post and an op-ed rather than direct communication with these valuable experts, the announcement of new ACIP members by X before onboarding and vetting have completed, and the release of term of reference for an ACIP workgroup that ignored all feedback from career staff at CDC.

The recent change in the adult and children’s immunization schedule threaten the lives of the youngest Americans and pregnant people. The data analyses that supported this decision have never been shared with CDC despite my respectful requests to HHS and other leadership. This lack of meaningful engagement was further compounded by a “frequently asked questions” document written to support the Secretary’s directive that was circulated by HHS without input from CDC subject matter experts and that cited studies that did not support the conclusions that were attributed to these authors. Having worked in local and national public health for years, I have never experienced such radical non-transparency, nor have I seen such unskilled manipulation of data to achieve a political end rather than the good of the American people. It is untenable to serve in an organization that is not afforded the opportunity to discuss decisions of scientific and public health importance released under the moniker of CDC. The lack of communication by HHS and other CDC political leadership that culminates in social media posts announcing major policy changes without prior notice demonstrate a disregard of normal communication channels and common sense. Having to retrofit analyses and policy actions to match inadequately thought-out announcements in poorly scripted videos or page long X posts should not be how organizations responsible for the health of people should function. Some examples include the announcement of the change in the COVID-19 recommendations for children and pregnant people, the firing of scientists from ACIP by X post and an op-ed rather than direct communication with these valuable experts, the announcement of new ACIP members by X before onboarding and vetting have completed, and the release of term of reference for an ACIP workgroup that ignored all feedback from career staff at CDC.

Their desire to please a political base will result in death and disability of vulnerable children and adults.  Their base should be the people they serve not a political voting bloc.

I have always been first to challenge scientific and public health dogma in my career and was excited by the opportunity to do so again.  I was optimistic that there would be an opportunity to brief the Secretary about key topics such as measles, avian influenza, and the highly coordinated approach to the respiratory virus season.  Such briefings would allow exchange of ideas and a shared path to support the vision of “Making America Healthy Again.”  We are seven months into the new administration, and no CDC subject matter expert from my Center has ever briefed the Secretary.  I am not sure who the Secretary is listening to, but it is quite certainly not to us.  Unvetted and conflicted outside organizations seem to be the sources HHS use over the gold standard science of CDC and other reputable sources.  At a hearing, Secretary Kennedy said that Americans should not take medical advice from him.  To the contrary, an appropriately briefed and inquisitive Secretary should be a source of health information for the people he serves. As it stands now, I must agree with him, that he should not be considered a source of accurate information.

The intentional eroding of trust in low-risk vaccines favoring natural infection and unproven remedies will bring us to a pre-vaccine era where only the strong will survive and many if not all will suffer.  I believe in nutrition and exercise.  I believe in making our food supply healthier, and I also believe in using vaccines to prevent death and disability.  Eugenics plays prominently in the rhetoric being generated and is derivative of a legacy that good medicine and science should continue to shun.

Their desire to please a political base will result in death and disability of vulnerable children and adults. Their base should be the people they serve not a political voting bloc. I have always been first to challenge scientific and public health dogma in my career and was excited by the opportunity to do so again. I was optimistic that there would be an opportunity to brief the Secretary about key topics such as measles, avian influenza, and the highly coordinated approach to the respiratory virus season. Such briefings would allow exchange of ideas and a shared path to support the vision of “Making America Healthy Again.” We are seven months into the new administration, and no CDC subject matter expert from my Center has ever briefed the Secretary. I am not sure who the Secretary is listening to, but it is quite certainly not to us. Unvetted and conflicted outside organizations seem to be the sources HHS use over the gold standard science of CDC and other reputable sources. At a hearing, Secretary Kennedy said that Americans should not take medical advice from him. To the contrary, an appropriately briefed and inquisitive Secretary should be a source of health information for the people he serves. As it stands now, I must agree with him, that he should not be considered a source of accurate information. The intentional eroding of trust in low-risk vaccines favoring natural infection and unproven remedies will bring us to a pre-vaccine era where only the strong will survive and many if not all will suffer. I believe in nutrition and exercise. I believe in making our food supply healthier, and I also believe in using vaccines to prevent death and disability. Eugenics plays prominently in the rhetoric being generated and is derivative of a legacy that good medicine and science should continue to shun.

The recent shooting at CDC is not why I am resigning.  My grandfather, who I am named after, stood up to fascist forces in Greece and lost his life doing so.  I am resigning to make him and his legacy proud.   I am resigning because of the cowardice of a leader that cannot admit that HIS and his minions’ words over decades created an environment where violence like this can occur.  I reject his and his colleagues’ thoughts and prayers, and advise they direct those to people that they have not actively harmed.

For decades, I have been a trusted voice for the LGBTQ community when it comes to critical health topics.  I must also cite the recklessness of the administration in their efforts to erase transgender populations, cease critical domestic and international HIV programming, and terminate key research to support equity as part of my decision.

Public health is not merely about the health of the individual, but it is about the health of the community, the nation, the world. The nation’s health security is at risk and is in the hands of people focusing on ideological self-interest.

I want to express my heartfelt gratitude for the opportunities for growth, learning, and collaboration that I have been afforded during my time at the CDC. It has been a privilege to work alongside such dedicated professionals who are committed to improving the health and well-being of communities across the nation even when under attack from within both physically and psychologically.

Thank you once again for the support and guidance I have received from you and previous CDC leadership throughout my tenure. I wish the CDC continued success in its vital mission and that HHS reverse its dangerous course to dismantle public health as a practice and as an institution.  If they continue the current path, they risk our personal well-being and the security of the United States.

The recent shooting at CDC is not why I am resigning. My grandfather, who I am named after, stood up to fascist forces in Greece and lost his life doing so. I am resigning to make him and his legacy proud. I am resigning because of the cowardice of a leader that cannot admit that HIS and his minions’ words over decades created an environment where violence like this can occur. I reject his and his colleagues’ thoughts and prayers, and advise they direct those to people that they have not actively harmed. For decades, I have been a trusted voice for the LGBTQ community when it comes to critical health topics. I must also cite the recklessness of the administration in their efforts to erase transgender populations, cease critical domestic and international HIV programming, and terminate key research to support equity as part of my decision. Public health is not merely about the health of the individual, but it is about the health of the community, the nation, the world. The nation’s health security is at risk and is in the hands of people focusing on ideological self-interest. I want to express my heartfelt gratitude for the opportunities for growth, learning, and collaboration that I have been afforded during my time at the CDC. It has been a privilege to work alongside such dedicated professionals who are committed to improving the health and well-being of communities across the nation even when under attack from within both physically and psychologically. Thank you once again for the support and guidance I have received from you and previous CDC leadership throughout my tenure. I wish the CDC continued success in its vital mission and that HHS reverse its dangerous course to dismantle public health as a practice and as an institution. If they continue the current path, they risk our personal well-being and the security of the United States.

Full resignation letter from Demetre C. Daskalakis, a CDC leader, does not hold back.
"The recent shooting at CDC is not why I am resigning. My grandfather, who I am named after, stood up to fascist forces in Greece and lost his life doing so. I am resigning to make him and his legacy proud."

28.08.2025 01:01 — 👍 6683    🔁 2410    💬 75    📌 242

@alexhgo is following 20 prominent accounts